Sevelamer hydrochloride

Product Name: Sevelamer hydrochloride
CAS No.: 152751-57-0
Chemical Name: Sevelamer hydrochloride
Synonyms: Sevelemar;SEVELAMER HCL;Sevelamer-001;Tianeptinic acid;SevelaMer HCL API;Sevelamer Hydrochloride;Sevelamer Hydrochloride (100 mg);Sevelamer hydrochloride USP/EP/BP;Sevelamer hydrochloride Impurities;TIANFU-CHEM Sevelamer hydrochloride
CBNumber: CB91012045
Molecular Formula: C6H13Cl2NO
Formula Weight: 186.08
MOL File: 152751-57-0.mol

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Sevelamer hydrochloride Property

storage temp.: Store at -20°C
solubility: Hot Methanol (Sparingly)
form: Solid
color: Pale Yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: S256000
Product name: SevelamerHydrochloride(TechnicalGrade)
Packaging: 500mg
Price: $225
Updated: 2021/12/16

AK Scientific

Product number: E121
Product name: Sevelamerhydrochloride
Packaging: 500mg
Price: $225
Updated: 2021/12/16

ChemScene

Product number: CS-3149
Product name: Sevelamerhydrochloride
Purity: >98.0%
Packaging: 500mg
Price: $324
Updated: 2021/12/16

ChemScene

Product number: CS-3149
Product name: Sevelamerhydrochloride
Purity: >98.0%
Packaging: 100mg
Price: $90
Updated: 2021/12/16

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Sevelamer hydrochloride Chemical Properties,Usage,Production

Originator

Renagel,Chugai Pharmaceutical

Uses

Sevelamer HCl is used in the treatment of hyperphosphataemia in patients suffering from chronic kidney disease.

Uses

Sevelamer hydrochloride is a noncalcemic phosphate binder for the treatment of hyperphosphatemia in chronic renal failure or patients suffering from chronic kidney disease.

Definition

ChEBI: Sevelamer hydrochloride is an epoxide.

Manufacturing Process

Poly(allylamine hydrochloride) (50% w/w, 426 kg) was charged to a 1000 L reactor and water (200 L) was added. Sodium hydroxide solution (32% w/w, 208 kg) was added, followed by 85 L of water. The mixture was stirred for 1 h and filtered to a 2500 L reactor. The transfer line was rinsed with water (217 kg) and acetonitrile (1300 L) added. The temperature was adjusted to 40°C and epichlorohydrin (20 kg) added. The mixture was stirred at 40° to 50°C for 1.5 h and then heated to reflux for 16 h. The resulting product slurry may be isolated and washed in decanter centrifuge.

brand name

Renagel (Genzyme).

Therapeutic Function

Antihyperphosphatemic

Veterinary Drugs and Treatments

Sevalamer may be useful for treating hyperphosphatemia associated with chronic renal failure, particularly when oral aluminum salts are not tolerated.

Sevelamer hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Sevelamer hydrochloride Suppliers

Canada 1 China 128 Europe 2 India 24 United Kingdom 3 United States 19 Global 177

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

shilang(zhuoli group)-pharma(nanjing) co.,ltd.

Tel: 86-25-87797880,81,82 -809
Fax: 86-25-85318152
Email: shilang@shilang-pharma.com
Country: China
ProdList: 40
Advantage: 55

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: meilunui@163.com
Country: China
ProdList: 4727
Advantage: 58

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View Lastest Price from Sevelamer hydrochloride manufacturers

Wuhan Boyuan Import & Export Co., LTD

Product: Sevelamer hydrochloride 152751-57-0
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000tons
Release date: 2023-07-31

Weijer International Trade (Hebei) Co., Ltd

Product: Sevelamer hydrochloride 152751-57-0
Price: US $5.00/kg
Min. Order: 1kg
Purity: >99%
Supply Ability: 300000ton
Release date: 2023-03-14

Dideu Industries Group Limited

Product: Sevelamer hydrochloride 152751-57-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-04

152751-57-0, Sevelamer hydrochlorideRelated Search:

Sevelamer carbonate 1-Bromo-2,3-epoxypropane Triethylamine PROPYLENE Triethanolamine Epichlorohydrin Propylene oxide Bis(2-ethylhexyl)amine ETHYLENE OXIDE N-Ethylmethylamine Butyl glycidyl ether Topotecan hydrochloride Sevelamer METHYL ISOCYANOACETATE COBALT(II) ACETYLACETONATE Benzyl isocyanide Tosylmethyl isocyanide SALCOMINE

SEVELAMER HCL

Sevelemar

Sevelamer Hydrochloride

2-Propen-1-amine - 2-(chloromethyl)oxirane (1:1)

Sevelamer-001

2-Propen-1-amine polymer with (chloromethyl)oxirane hydrochloride

(ChloroMethyl)oxirane polyMer with 2-Propen-1-aMine Hydrochloride

2-Propen-1-aMine Hydrochloride polyMer with 2-(ChloroMethyl)oxirane

AllylaMine Hydrochloride-epichlorohydrin CopolyMer

SevelaMer HCL API

SevelaMer Hydrochloride DISCONTINUED See : S256000

Sevelamer hydrochloride 2-Propen-1-amine polymer with (chloromethyl)oxirane hydrochloride

2-Propen-1-amine, hydrochloride (1:1), polymer with 2-(chloromethyl)oxirane

Sevelamer hydrochloride(152751-57-0)

Sevelamer hydrochloride USP/EP/BP

Sevelamer hydrochloride Impurities

Tianeptinic acid

TIANFU-CHEM Sevelamer hydrochloride

Sevelamer Hydrochloride (100 mg)

152751-57-0

C3H7NmC3H5ClOnHClx

C3H7NC3H5ClOHClx

C6H12NClO

Other APIs

Inhibitors

Pharmaceutical intermediate

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals