Sevelamer hydrochloride

Product Name: Sevelamer hydrochloride
CAS No.: 152751-57-0
Chemical Name: Sevelamer hydrochloride
Synonyms: Sevelemar;SEVELAMER HCL;Sevelamer-001;Tianeptinic acid;SevelaMer HCL API;Sevelamer Hydrochloride;Sevelamer Hydrochloride (100 mg);Sevelamer hydrochloride USP/EP/BP;Sevelamer hydrochloride Impurities;TIANFU-CHEM Sevelamer hydrochloride
CBNumber: CB91012045
Molecular Formula: C6H13Cl2NO
Formula Weight: 186.08
MOL File: 152751-57-0.mol

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Sevelamer hydrochloride Property

storage temp.: Store at -20°C
solubility: Hot Methanol (Sparingly)
form: Solid
color: Pale Yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: S256000
Product name: SevelamerHydrochloride(TechnicalGrade)
Packaging: 500mg
Price: $225
Updated: 2021/12/16

ChemScene

Product number: CS-3149
Product name: Sevelamerhydrochloride
Purity: >98.0%
Packaging: 100mg
Price: $90
Updated: 2021/12/16

AK Scientific

Product number: E121
Product name: Sevelamerhydrochloride
Packaging: 500mg
Price: $225
Updated: 2021/12/16

ChemScene

Product number: CS-3149
Product name: Sevelamerhydrochloride
Purity: >98.0%
Packaging: 500mg
Price: $324
Updated: 2021/12/16

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Sevelamer hydrochloride Chemical Properties,Usage,Production

Originator

Renagel,Chugai Pharmaceutical

Uses

Sevelamer HCl is used in the treatment of hyperphosphataemia in patients suffering from chronic kidney disease.

Uses

Sevelamer hydrochloride is a noncalcemic phosphate binder for the treatment of hyperphosphatemia in chronic renal failure or patients suffering from chronic kidney disease.

Definition

ChEBI: Sevelamer hydrochloride is an epoxide.

Manufacturing Process

Poly(allylamine hydrochloride) (50% w/w, 426 kg) was charged to a 1000 L reactor and water (200 L) was added. Sodium hydroxide solution (32% w/w, 208 kg) was added, followed by 85 L of water. The mixture was stirred for 1 h and filtered to a 2500 L reactor. The transfer line was rinsed with water (217 kg) and acetonitrile (1300 L) added. The temperature was adjusted to 40°C and epichlorohydrin (20 kg) added. The mixture was stirred at 40° to 50°C for 1.5 h and then heated to reflux for 16 h. The resulting product slurry may be isolated and washed in decanter centrifuge.

brand name

Renagel (Genzyme).

Therapeutic Function

Antihyperphosphatemic

Veterinary Drugs and Treatments

Sevalamer may be useful for treating hyperphosphatemia associated with chronic renal failure, particularly when oral aluminum salts are not tolerated.

Sevelamer hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Sevelamer hydrochloride Suppliers

Canada 1 China 128 Europe 2 India 24 United Kingdom 3 United States 19 Global 177

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

LGM Pharma

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Country: United States
ProdList: 2123
Advantage: 70

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
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MedChemexpress LLC

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HBCChem, Inc.

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Country: United States
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Advantage: 60

Target molecule Corp.

Tel: 857-239-0968
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Country: United States
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TargetMol Chemicals Inc.

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Protheragen-ING

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TargetMol Chemicals Inc.

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HBCChem Inc.

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MedChemExpress

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NAVINTA LLC

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ACIC Fine Chemicals Inc.

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Chembargains

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HONEST JOY HOLDINGS LIMITED

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2A PharmaChem USA

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3B Scientific Corporation

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AK Scientific, Inc.

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View Lastest Price from Sevelamer hydrochloride manufacturers

Wuhan Boyuan Import & Export Co., LTD

Product: Sevelamer hydrochloride 152751-57-0
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000tons
Release date: 2023-07-31

Weijer International Trade (Hebei) Co., Ltd

Product: Sevelamer hydrochloride 152751-57-0
Price: US $5.00/kg
Min. Order: 1kg
Purity: >99%
Supply Ability: 300000ton
Release date: 2023-03-14

Dideu Industries Group Limited

Product: Sevelamer hydrochloride 152751-57-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-04

152751-57-0, Sevelamer hydrochlorideRelated Search:

Sevelamer carbonate 1-Bromo-2,3-epoxypropane Triethylamine PROPYLENE Triethanolamine Epichlorohydrin Propylene oxide Bis(2-ethylhexyl)amine ETHYLENE OXIDE N-Ethylmethylamine Butyl glycidyl ether Topotecan hydrochloride Sevelamer METHYL ISOCYANOACETATE COBALT(II) ACETYLACETONATE Benzyl isocyanide Tosylmethyl isocyanide SALCOMINE

SEVELAMER HCL

Sevelemar

Sevelamer Hydrochloride

2-Propen-1-amine - 2-(chloromethyl)oxirane (1:1)

Sevelamer-001

2-Propen-1-amine polymer with (chloromethyl)oxirane hydrochloride

(ChloroMethyl)oxirane polyMer with 2-Propen-1-aMine Hydrochloride

2-Propen-1-aMine Hydrochloride polyMer with 2-(ChloroMethyl)oxirane

AllylaMine Hydrochloride-epichlorohydrin CopolyMer

SevelaMer HCL API

SevelaMer Hydrochloride DISCONTINUED See : S256000

Sevelamer hydrochloride 2-Propen-1-amine polymer with (chloromethyl)oxirane hydrochloride

2-Propen-1-amine, hydrochloride (1:1), polymer with 2-(chloromethyl)oxirane

Sevelamer hydrochloride(152751-57-0)

Sevelamer hydrochloride USP/EP/BP

Sevelamer hydrochloride Impurities

Tianeptinic acid

TIANFU-CHEM Sevelamer hydrochloride

Sevelamer Hydrochloride (100 mg)

152751-57-0

C3H7NmC3H5ClOnHClx

C3H7NC3H5ClOHClx

C6H12NClO

Other APIs

Inhibitors

Pharmaceutical intermediate

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals