ChemicalBook > CAS DataBase List > Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI)

Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI)

Product Name
Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI)
CAS No.
697739-13-2
Chemical Name
Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI)
Synonyms
Imidazo[1,5-a]pyridine-8-carboxylic acid;iMidazol[1,5-a]pyridine-8-carboxylic acid;H-imidazo[1,5-a]pyridine-8-carboxylic acid;Imidazo[1,5-a]pyridine-8-carboxylic acid 98%;Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI)
CBNumber
CB91052542
Molecular Formula
C8H6N2O2
Formula Weight
162.15
MOL File
697739-13-2.mol
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Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI) Property

Density 
1.41
storage temp. 
Sealed in dry,Room Temperature
form 
solid
color 
Yellow
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
I387560
Product name
Imidazo[1,5-a]pyridine-8-carboxylicacid
Packaging
250mg
Price
$220
Updated
2021/12/16
TRC
Product number
I387560
Product name
Imidazo[1,5-a]pyridine-8-carboxylicacid
Packaging
500mg
Price
$360
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0392719
Product name
IMIDAZO[1,5-A]PYRIDINE-8-CARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$496.39
Updated
2021/12/16
Matrix Scientific
Product number
073640
Product name
Imidazo[1,5-a]pyridine-8-carboxylic acid
Purity
95+%
Packaging
500mg
Price
$530
Updated
2021/12/16
Activate Scientific
Product number
AS16284
Product name
Imidazo[1,5-a]pyridine-8-carboxylicacid
Purity
95+%
Packaging
1g
Price
$734
Updated
2021/12/16
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Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI) Chemical Properties,Usage,Production

Synthesis

697739-12-1

697739-13-2

1. ethyl imidazo[1,5-a]pyridine-8-carboxylate (8.67 g, 45.6 mmol) and potassium hydroxide (91.2 ml, 91.2 mmol, 1 M methanol solution) were mixed in a reaction vial. 2. The reaction mixture was heated and refluxed for 30 min, and the progress of the reaction was monitored by HPLC until the reaction was complete. 3. Upon completion of the reaction, the mixture was cooled and concentrated to dryness in a rotary evaporation The mixture was concentrated to dryness in a rotary evaporator.4. Water (50 ml) was added to the residue, which was subsequently acidified with 2N hydrochloric acid solution to pH<7, where a yellow precipitate was formed.5. The precipitate was collected by filtration and washed with water, ethanol, and ether in that order.6. After drying, imidazo[1,5-A]pyridine-8-carboxylic acid (3.1 g, 42% yield) was obtained as a yellow solid.

References

[1] Patent: WO2004/46133, 2004, A1. Location in patent: Page 32
[2] Patent: WO2005/28445, 2005, A2. Location in patent: Page/Page column 28

Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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Imidazo[1,5-a]pyridine-8-carboxylic acid (9CI) Suppliers

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