4-Aminomethyl-1-methylpyrazole

Product Name: 4-Aminomethyl-1-methylpyrazole
CAS No.: 400877-05-6
Chemical Name: 4-Aminomethyl-1-methylpyrazole
Synonyms: (1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE;(1-Methyl-1H-pyrazol-4-yl)methylamine;AKOS B000529;AKOS PAO-0126;TIMTEC-BB SBB000039;ART-CHEM-BB B000529;4-Aminomethyl-1-methylpyrazole;(1-methylpyrazol-4-yl)methanamine;(1-methyl-4-pyrazolyl)methanamine;(1-methylpyrazol-4-yl)methylamine
CBNumber: CB9111330
Molecular Formula: C5H9N3
Formula Weight: 111.15
MOL File: 400877-05-6.mol

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4-Aminomethyl-1-methylpyrazole Property

Boiling point:: 220 °C
Density: 1.16
Flash point:: 87 °C
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 8.98±0.29(Predicted)
Appearance: Colorless to light yellow Liquid

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
HazardClass: IRRITANT
HS Code: 2933199090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: M330363
Product name: (1-Methyl-1H-pyrazol-4-yl)methanamine
Packaging: 250mg
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 027024
Product name: (1-Methyl-1H-pyrazol-4-yl)methylamine
Packaging: 500mg
Price: $25
Updated: 2021/12/16

Matrix Scientific

Product number: 027024
Product name: (1-Methyl-1H-pyrazol-4-yl)methylamine
Packaging: 1g
Price: $39
Updated: 2021/12/16

AK Scientific

Product number: Y5423
Product name: (1-Methyl-1H-pyrazol-4-yl)methanamine
Packaging: 250mg
Price: $89
Updated: 2021/12/16

Apolloscientific

Product number: OR318083
Product name: 1-(1-Methyl-1H-pyrazol-4-yl)methanamine
Packaging: 1g
Price: $102
Updated: 2021/12/16

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4-Aminomethyl-1-methylpyrazole Chemical Properties,Usage,Production

Synthesis

43193-15-3

400877-05-6

The general procedure for the synthesis of 4-(aminomethyl)-1-methylpyrazole from the compound (CAS:43193-15-3) was as follows: the oxime 1a-k (23 mmol) was dissolved in isopropanol (100 mL), and the solution was transferred to an autoclave equipped with fluoroplastic liners. Subsequently, concentrated hydrochloric acid (10.5 mL) was added and a piece of regenerated catalyst was introduced. The hydrogenation reaction was carried out at 20 °C and 10 atm hydrogen pressure for 3-5 h, during which the reaction conditions were kept constant. The reaction process was monitored by thin layer chromatography (TLC). After complete consumption of the starting oxime, the reaction solution was poured out of the autoclave and the catalyst block was washed with methanol (3 × 30 mL), the washes were combined and mechanical impurities were removed by filtration. After evaporation of the solvent, analytically pure aromatic benzylamines 3a-k were obtained.If the hydrogenation reaction was carried out in methanol (100 mL), the solvent was removed and the residue was subsequently dried by azeotropic distillation using isopropanol (250 mL). For the hydrogenation of compound 1k, the reaction mixture is additionally reacted with activated carbon for 1 hour. The catalyst block was regenerated directly in the reactor at 400 °C in a stream of hydrogen for the subsequent hydrogenation process.

References

[1] Russian Chemical Bulletin, 2018, vol. 67, # 8, p. 1394 - 1400
[2] Izv. Akad. Nauk, Ser. Khim., 2018, # 8, p. 1394 - 1400,7

4-Aminomethyl-1-methylpyrazole Preparation Products And Raw materials

Raw materials

Ethanol 3-(DIMETHYLAMINO)ACRYLONITRILE Tetrahydrofuran Lithium Aluminum Hydride N,N-Dimethylformamide dimethyl acetal

Preparation Products

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4-Aminomethyl-1-methylpyrazole Suppliers

China 76 Germany 3 India 1 Russia 1 Ukraine 1 United Kingdom 4 United States 19 Global 105

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View Lastest Price from 4-Aminomethyl-1-methylpyrazole manufacturers

Career Henan Chemical Co

Product: 4-Aminomethyl-1-methylpyrazole 400877-05-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-03

400877-05-6, 4-Aminomethyl-1-methylpyrazoleRelated Search:

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TIMTEC-BB SBB000039

AKOS PAO-0126

AKOS B000529

1-(1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE

C-(1-METHYL-1H-PYRAZOL-4-YL)-METHYLAMINE

ART-CHEM-BB B000529

(1-Methyl-1H-pyrazol-4-yl)methylamine

4-Aminomethyl-1-methylpyrazole

(1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE

(1-methyl-4-pyrazolyl)methanamine

(1-methylpyrazol-4-yl)methanamine

(1-methylpyrazol-4-yl)methylamine

(1-methylpyrazol-4-yl)methanamineamine

1-Methyl-1H-Pyrazole-4-MethanaMine

4-AMinoMethyl-1-Methylpyrazole (HCl forM)

1H-Pyrazole-4-methanamine, 1-methyl-

1-(1-methyl-1H-pyrazol-4-yl)methylamine

400877-05-6