Ethyl O-mesitylsulfonylacetohydroxamate
- Product Name
- Ethyl O-mesitylsulfonylacetohydroxamate
- CAS No.
- 38202-27-6
- Chemical Name
- Ethyl O-mesitylsulfonylacetohydroxamate
- Synonyms
- Ethyl N-(Mesitylsulfonyl)oxyacetiMidate;(E)-ethyl N-(Mesitylsulfonyl)oxyacetiMidate;Ethyl O-mesitylsulfo;ETHYL O-MESITYLSULFONYLACETOHYDROXAMATE;ethyl O-methylsulphonylacetohydroxamate;Ethyl O-methylsulfonylacetohydroxamate.;Ethyl o-(mesitylsulfonyl)acetohydroximate;ethyl O-mesitylenesulfonylacetohydroxamate;Ethyl N-[(mesitylsulfonyl)oxy]ethanimidate;Ethyl O-mesitylsulfonylacetohydroxamate,99%
- CBNumber
- CB9118081
- Molecular Formula
- C13H19NO4S
- Formula Weight
- 285.36
- MOL File
- 38202-27-6.mol
Ethyl O-mesitylsulfonylacetohydroxamate Property
- Melting point:
- 54-56 °C (lit.) 54-58 °C
- Boiling point:
- 381.7±52.0 °C(Predicted)
- Density
- 1.2483 (rough estimate)
- refractive index
- 1.6800 (estimate)
- storage temp.
- 2-8°C
- form
- powder to crystal
- color
- White to Almost white
- Water Solubility
- Insoluble
- BRN
- 2144156
- InChI
- InChI=1S/C13H19NO4S/c1-6-17-12(5)14-18-19(15,16)13-10(3)7-9(2)8-11(13)4/h7-8H,6H2,1-5H3
- InChIKey
- KQCBSWBQAXTILK-UHFFFAOYSA-N
- SMILES
- C(=NOS(C1=C(C)C=C(C)C=C1C)(=O)=O)(OCC)C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 63936
- Product name
- Ethyl O-(2-mesitylenesulfonyl)acethydroxamate
- Purity
- purum, ≥97.0% (HPLC)
- Packaging
- 5G
- Price
- $124
- Updated
- 2025/07/31
- Product number
- 63936
- Product name
- Ethyl O-(2-mesitylenesulfonyl)acethydroxamate
- Purity
- purum, ≥97.0% (HPLC)
- Packaging
- 25G
- Price
- $486
- Updated
- 2025/07/31
- Product number
- 63936
- Product name
- Ethyl O-(2-mesitylenesulfonyl)acethydroxamate
- Purity
- purum, ≥97.0% (HPLC)
- Packaging
- 5g-f
- Price
- $114
- Updated
- 2021/12/16
- Product number
- M1182
- Product name
- Ethyl O-Mesitylsulfonylacetohydroxamate [Precursor of the Powerful Aminating Reagent]
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 1g
- Price
- $32
- Updated
- 2025/07/31
- Product number
- M1182
- Product name
- Ethyl O-Mesitylsulfonylacetohydroxamate [Precursor of the Powerful Aminating Reagent]
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $93
- Updated
- 2025/07/31
Ethyl O-mesitylsulfonylacetohydroxamate Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystalline powder
Synthesis Reference(s)
The Journal of Organic Chemistry, 38, p. 1239, 1973 DOI: 10.1021/jo00946a045
Synthesis
773-64-8
10576-12-2
38202-27-6
Ethyl N-hydroxyacetimidate (2.00 g, 19.4 mmol), N,N-diisopropylethylamine (3.01 g, 23.3 mmol), and 4-dimethylaminopyridine (240 mg, 1.96 mmol) were dissolved in anhydrous dichloromethane (30 mL) and the solution was cooled to 0°C. To the cooled solution was slowly added, with stirring, 2,4,6 -trimethylbenzene-1-sulfonyl chloride (4.66 g, 21.3 mmol) to the cooled solution. The reaction mixture was gradually warmed to room temperature and stirring was continued for 1 hour. Upon completion of the reaction, the reaction was quenched by the addition of water (40 mL) and subsequently extracted with dichloromethane (30 mL, 3 times). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel fast column chromatography using a hexane solution of 5% ethyl acetate as eluent to afford ethyl O-(2,4,6-trimethylbenzenesulfonyl)acetohydroxamic acid as a white solid (5.19 g, 94% yield). The product was characterized by 1H NMR (400 MHz, CDCl3), 13C NMR (101 MHz, CDCl3) and HRMS (ESI/TOF), and the data were consistent with the expected structure.
References
[1] RSC Advances, 2018, vol. 8, # 25, p. 13755 - 13763
[2] Synthetic Communications, 2018, vol. 48, # 6, p. 626 - 631
[3] Patent: WO2011/112186, 2011, A1. Location in patent: Page/Page column 202
[4] Patent: CN108530315, 2018, A. Location in patent: Paragraph 0100-0102
[5] Journal of Heterocyclic Chemistry, 2007, vol. 44, # 6, p. 1383 - 1387
Ethyl O-mesitylsulfonylacetohydroxamate Preparation Products And Raw materials
Raw materials
Preparation Products
Ethyl O-mesitylsulfonylacetohydroxamate Suppliers
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- Switzerland
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View Lastest Price from Ethyl O-mesitylsulfonylacetohydroxamate manufacturers
- Product
- Ethyl N-[(mesitylsulfonyl)oxy]ethanimidate 38202-27-6
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2025-09-08
- Product
- Ethyl O-mesitylsulfonylacetohydroxamate 38202-27-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 200KG
- Release date
- 2019-08-30