4-(cyclohexylsulfamoyl)benzoic acid

Product Name: 4-(cyclohexylsulfamoyl)benzoic acid
CAS No.: 6314-70-1
Chemical Name: 4-(cyclohexylsulfamoyl)benzoic acid
Synonyms: NSC23005;INK4C-IN-2;NSC23005 free acid;NSC23005, 10 mM in DMSO;4-(N-Cyclohexylsulfamoyl)benzoic acid;Benzoic acid, 4-[(cyclohexylamino)sulfonyl]-
CBNumber: CB91257767
Molecular Formula: C13H17NO4S
Formula Weight: 283.34
MOL File: 6314-70-1.mol

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4-(cyclohexylsulfamoyl)benzoic acid Property

Melting point:: 259-260 °C
Boiling point:: 473.4±47.0 °C(Predicted)
Density: 1.36±0.1 g/cm3(Predicted)
pka: 3.54±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CHM0296513
Product name: 4-(CYCLOHEXYLSULFAMOYL)BENZOIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $498.92
Updated: 2021/12/16

DC Chemicals

Product number: DC9989
Product name: NSC23005freeacid
Purity: >98%
Packaging: 1g
Price: $1200
Updated: 2021/12/16

DC Chemicals

Product number: DC9989
Product name: NSC23005freeacid
Purity: >98%
Packaging: 100mg
Price: $350
Updated: 2021/12/16

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4-(cyclohexylsulfamoyl)benzoic acid Chemical Properties,Usage,Production

Description

NSC23005 is a p18INK inhibitor. NSC23005 potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM).

Uses

INK4C-IN-2 (Compound 40) is the inhibitor for INK4C (also known as p18) and the activator for CDK4/6. INK4C-IN-2 increases the number and expansion capacity of mouse and human hematopoietic stem cells (HSCs) with EC50 of 5.21 nM, promotes the self-renewal and multilineage differentiation of HSCs. INK4C-IN-2 improves the expansion and long-term hematopoietic reconstruction ability of HSCs in mouse bone marrow transplantation model[1].

References

[1] Xie XQ, et al., Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci Rep. 2015 Dec 18;5:18115. DOI:10.1038/srep18115

4-(cyclohexylsulfamoyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-(cyclohexylsulfamoyl)benzoic acid manufacturers

Career Henan Chemical Co

Product: 4-(cyclohexylsulfamoyl)benzoic acid 6314-70-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-25

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NSC23005

NSC23005 free acid

4-(N-Cyclohexylsulfamoyl)benzoic acid

Benzoic acid, 4-[(cyclohexylamino)sulfonyl]-

NSC23005, 10 mM in DMSO

INK4C-IN-2

6314-70-1