ChemicalBook > CAS DataBase List > 2(3H)-Benzoxazolone,7-amino-(9CI)
2(3H)-Benzoxazolone,7-amino-(9CI)
- Product Name
- 2(3H)-Benzoxazolone,7-amino-(9CI)
- CAS No.
- 81282-60-2
- Chemical Name
- 2(3H)-Benzoxazolone,7-amino-(9CI)
- Synonyms
- Pardoprunox Impurity 1;7-Amino-2-benzoxazolone;7-Amino-2-benzoxazolinone;7-Aminobenzoxazol-2(3H)-one;7-Amino-2-benzoxazolinone>7-Amino-2-hydroxybenzoxazole;2(3H)-Benzoxazolone, 7-amino-;7-Aminobenzo[d]oxazol-2(3H)-one;7-amino-3h-1,3-benzoxazol-2-one;7-Amino-1,3-benzoxazol-2(3H)-one
- CBNumber
- CB91281906
- Molecular Formula
- C7H6N2O2
- Formula Weight
- 150.13
- MOL File
- 81282-60-2.mol
More
Less
2(3H)-Benzoxazolone,7-amino-(9CI) Property
- Density
- 1.438±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- soluble in Acetone, Chloroform, Ethyl Acetate, Methanol
- form
- powder to crystal
- pka
- 9.06±0.70(Predicted)
- color
- White to Yellow to Orange
More
Less
Safety
- HS Code
- 2934999090
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
TCI Chemical
- Product number
- A2806
- Product name
- 7-Amino-2-benzoxazolinone
- Purity
- >95.0%(GC)(T)
- Packaging
- 250mg
- Price
- $40
- Updated
- 2025/07/31
TCI Chemical
- Product number
- A2806
- Product name
- 7-Amino-2-benzoxazolinone
- Purity
- >95.0%(GC)(T)
- Packaging
- 1g
- Price
- $110
- Updated
- 2025/07/31
TRC
- Product number
- A593750
- Product name
- 7-Amino-2(3H)-benzoxazolone
- Packaging
- 250mg
- Price
- $1100
- Updated
- 2021/12/16
AK Scientific
- Product number
- 2624AC
- Product name
- 7-Aminobenzo[d]oxazol-2(3H)-one
- Packaging
- 100mg
- Price
- $88
- Updated
- 2021/12/16
AK Scientific
- Product number
- 2624AC
- Product name
- 7-Aminobenzo[d]oxazol-2(3H)-one
- Packaging
- 1g
- Price
- $138
- Updated
- 2021/12/16
More
Less
2(3H)-Benzoxazolone,7-amino-(9CI) Chemical Properties,Usage,Production
Chemical Properties
Tan Solid
Uses
Intermediate for the preparation of bifeprunox mesylate
Synthesis
811810-67-0
81282-60-2
General procedure for the synthesis of 7-amino-2(3H)-benzoxazolone from 5-chloro-7-nitrobenzo[d]oxazol-2(3H)-one: Compound 6 (4 g, 18.56 mmol) was dissolved in a 4:1 MeOH/DMF solvent mixture (50 ml) and 10% Pd/C catalyst (500 mg) was added. The hydrogenation reaction was carried out at 60 psi hydrogen pressure overnight. The progress of the reaction was monitored by TLC (unfolding agent ratio ethyl acetate:petroleum ether = 3:7). After completion of the reaction, the reaction mixture was filtered through a diatomaceous earth pad and the filtrate was concentrated under vacuum. The crude product was crystallized with ether to give 2.8 g of beige solid in 99% yield. The structure of the product was confirmed by 1HNMR (DMSO-d6, 200 MHz): δ5.31 (2H, bs, NH2), 6.26 (1H, dd, J = 7.6 Hz, J'= 1 Hz, Ar-H), 6.38 (1H, dd, J = 8.4 Hz, J'= 1.2 Hz, Ar-H), 6.80 (1H, t, J = 8 Hz, Ar-H), 11.32 (1H, bs, NH).
References
[1] Patent: EP2377850, 2011, A1. Location in patent: Page/Page column 22
[2] Patent: US2006/194812, 2006, A1. Location in patent: Page/Page column 6
[3] Patent: WO2005/16898, 2005, A2. Location in patent: Page/Page column 11
[4] Patent: US2006/40932, 2006, A1. Location in patent: Page/Page column 5
[5] Patent: US2010/119622, 2010, A1. Location in patent: Page/Page column 17
2(3H)-Benzoxazolone,7-amino-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
2(3H)-Benzoxazolone,7-amino-(9CI) Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- +86-021-54824098 15317552526
- Fax
- 021-54824069
- sales@chemzq.com
- Country
- China
- ProdList
- 254
- Advantage
- 55
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55
- Tel
- 0537-4531868 18553729317
- qfhdtc@126.com
- Country
- China
- ProdList
- 96
- Advantage
- 55
- Tel
- 0371-53765687 18937137882
- Fax
- QQ:2885373884
- 2853979813@qq.com
- Country
- China
- ProdList
- 7991
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 021-021-021-31663258 13795219287
- Fax
- 021-31663258
- donghuanwen@126.com
- Country
- China
- ProdList
- 8816
- Advantage
- 58
- Tel
- 021-16621358918; 18516310516
- Fax
- 13045646768
- zhenlipharma888@163.com
- Country
- China
- ProdList
- 19035
- Advantage
- 58
- Tel
- 025-58859352 18068836627
- Fax
- 02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 15083
- Advantage
- 58
- Tel
- 025-025-58470199 18351831988
- Fax
- 025-58470199
- sales@daqinpharma.cn
- Country
- China
- ProdList
- 312
- Advantage
- 58
- Tel
- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com
- Country
- China
- ProdList
- 57422
- Advantage
- 58
- Tel
- 028-84641798 18782128315
- 3302391190@qq.com
- Country
- China
- ProdList
- 9800
- Advantage
- 55
- Tel
- 0531-88977029 18396830603
- Fax
- 0531-88964879
- sales@boyuanpharm.com
- Country
- China
- ProdList
- 216
- Advantage
- 58
- Tel
- +8615056975894
- Fax
- 86-0551-62678551
- shawn@hirisunpharm.com
- Country
- CHINA
- ProdList
- 9911
- Advantage
- 58
- Tel
- 13981836672
- 2560370848@qq.com
- Country
- China
- ProdList
- 2807
- Advantage
- 58
- Tel
- 027-59207796 13429867250
- Fax
- 027-59207796
- w13429867250@163.com
- Country
- China
- ProdList
- 1995
- Advantage
- 58
- Tel
- 021-58461859 15821823057
- service@aiviche.com
- Country
- China
- ProdList
- 49312
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0086-371-86658258
- factory@coreychem.com
- Country
- China
- ProdList
- 29798
- Advantage
- 58
- Tel
- nanfengdrug@163.com; 18616377689
- nanfengdrug@163.com
- Country
- China
- ProdList
- 20009
- Advantage
- 58
- Tel
- 15871722230
- Fax
- 2796190295
- 15871722230@163.com
- Country
- China
- ProdList
- 4686
- Advantage
- 58
- Tel
- 17830741407
- Fax
- QQ：2479150351
- sales@chem47.com
- Country
- China
- ProdList
- 1768
- Advantage
- 58
- Tel
- 027-68897569 18120462897
- Fax
- 027-68897569
- fiona@yuanmengbio.com
- Country
- China
- ProdList
- 4657
- Advantage
- 58
- Tel
- 13180081292 13180081292
- contact@wetogethermed.com
- Country
- China
- ProdList
- 7943
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 40000
- Advantage
- 58
- Tel
- 400-880-2824; 13184580281
- Fax
- 400-880-2824
- hj@ruiweier.cn
- Country
- China
- ProdList
- 2686
- Advantage
- 58
- Tel
- 13475906826 18615616891
- zhangdong.0602@163.com
- Country
- China
- ProdList
- 143
- Advantage
- 58
- Tel
- +86(21)5895 0110 13124863828
- sales@linkchem.cn
- Country
- China
- ProdList
- 2999
- Advantage
- 58
- Tel
- 400-6005915
- sales@picasso-e.com
- Country
- China
- ProdList
- 39665
- Advantage
- 58
- Tel
- 400-880-2824 15608648206
- 1987516016@qq.com
- Country
- China
- ProdList
- 2671
- Advantage
- 58
- Tel
- 133-3998-5473 13339985473
- C13339985473@163.com
- Country
- China
- ProdList
- 4991
- Advantage
- 58
- Tel
- 18621169109
- market03@meryer.com
- Country
- China
- ProdList
- 27987
- Advantage
- 58
- Tel
- 13417589054;
- trendseenbio@gmail.com
- Country
- China
- ProdList
- 9069
- Advantage
- 58
- Tel
- 17362916295; 17362916295
- w17362916295@163.com
- Country
- China
- ProdList
- 3992
- Advantage
- 58
- Tel
- 13192879270; 13192879270
- 1525037351@qq.com
- Country
- China
- ProdList
- 3507
- Advantage
- 58
- Tel
- 029-029-81123119 17391733320
- 1021@dideu.com
- Country
- China
- ProdList
- 10001
- Advantage
- 58
- Tel
- 010-50973130 17801761073
- Gsiyu@solarbio.com
- Country
- China
- ProdList
- 50464
- Advantage
- 58
- Tel
- 021-57520305 13795461237
- zhuruyan@jskchem.com
- Country
- China
- ProdList
- 49234
- Advantage
- 58
- Tel
- 4000255188 13327728092
- sales@pharmablock.com
- Country
- China
- ProdList
- 10000
- Advantage
- 58
- Tel
- 021-54370211 18051886391
- 3007215920@qq.com
- Country
- China
- ProdList
- 2989
- Advantage
- 58
- Tel
- 13393721940
- sales@vcommend.com
- Country
- China
- ProdList
- 9963
- Advantage
- 58
- Tel
- 18600731423
- jason_gao@yl-pharminblock.com
- Country
- China
- ProdList
- 1952
- Advantage
- 58
- Tel
- 4008-099-669
- 23419001name@qq.com
- Country
- CHINA
- ProdList
- 6043
- Advantage
- 58
- Tel
- 021-60936350
- scbt@scbt.com
- Country
- China
- ProdList
- 6594
- Advantage
- 58
- Tel
- 18270980682
- mmwang@sunwaypharm.cn
- Country
- China
- ProdList
- 1790
- Advantage
- 58
- Tel
- 15890142075
- 3555133855@qq.com
- Country
- China
- ProdList
- 9853
- Advantage
- 58
More
Less
View Lastest Price from 2(3H)-Benzoxazolone,7-amino-(9CI) manufacturers
Career Henan Chemical Co
- Product
- 7-Amino-1,3-benzoxazol-2(3H)-one 81282-60-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-09
81282-60-2, 2(3H)-Benzoxazolone,7-amino-(9CI)Related Search:
Thianaphthene
Dibenzothiophene
2-(P-TOLYL)BENZOXAZOLE
Centchroman
Quinazoline
Diphenylamine
2(3H)-Benzoxazolone,7-amino-(9CI)
7-[4-[(3-phenylphenyl)methyl]piperazin-1-yl]-3H-benzooxazol-2-one
BIFEPRUNOX MESYLATE
7-PIPERAZIN-1-YL-3H-BENZOOXAZOL-2-ONE
5-Chloro-7-nitro-2(3H)-benzoxazolone