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(1'S,2'S)-NICOTINE 1'-OXIDE

Product Name
(1'S,2'S)-NICOTINE 1'-OXIDE
CAS No.
51095-86-4
Chemical Name
(1'S,2'S)-NICOTINE 1'-OXIDE
Synonyms
S,2’Nicotine Impurity 1;S)-Nicotine-1’Nicotine 1'-N-oxide;Nicotine-cis-N-oxide;(1's2's)-Nicotine-N'-oxide;(1'S,2'S)-NICOTINE 1'-OXIDE;(1S,2S)-syn-Nicotine N'-oxide;(1'S,2'S)-TRANS-NICOTINE 1'-OXIDE;(1'S,2'S)-trans-Nicotine-1'-N-oxide
CBNumber
CB9131437
Molecular Formula
C10H14N2O
Formula Weight
178.23
MOL File
Mol file
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(1'S,2'S)-NICOTINE 1'-OXIDE Property

Melting point:
182-183°C
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
DMF: 50 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
form 
A crystalline solid
pka
4.63±0.40(Predicted)
color 
White to off-white
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P311Call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16413
Product name
(1'S,2'S)-Nicotine-1'-oxide
Purity
≥98%
Packaging
25mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
16413
Product name
(1'S,2'S)-Nicotine-1'-oxide
Purity
≥98%
Packaging
50mg
Price
$176
Updated
2024/03/01
Cayman Chemical
Product number
16413
Product name
(1'S,2'S)-Nicotine-1'-oxide
Purity
≥98%
Packaging
100mg
Price
$330
Updated
2024/03/01
TRC
Product number
N427500
Product name
(1’S,2’S)-Nicotine1’-Oxide
Packaging
250mg
Price
$490
Updated
2021/12/16
TRC
Product number
N427500
Product name
(1’S,2’S)-Nicotine1’-Oxide
Packaging
100mg
Price
$180
Updated
2021/12/16
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(1'S,2'S)-NICOTINE 1'-OXIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White to Yellow Solid

Uses

Nicotine-1’-N-oxide is a derivative of Nicotine (N412420) found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as a metabolite of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1’-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans.

Uses

Nicotine-1’-N-oxide is a derivative of nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as a metabolite of nicotine in animals and in man. The metabolism of nicotine

Definition

ChEBI: Trans-(S)-nicotine N(1')-oxide is an (S)-nicotine N(1')-oxide in which the N(1')-methyl group is on the opposite side of the pyrrolidine ring to the pyridine substituent. The major species at pH 7.3.

(1'S,2'S)-NICOTINE 1'-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(1'S,2'S)-NICOTINE 1'-OXIDE Suppliers

Canada 1 China 25 India 3 United Kingdom 2 United States 6 Global 37
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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021-50135380
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0755-28967200 13631290199
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Aikon International Limited
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51095-86-4, (1'S,2'S)-NICOTINE 1'-OXIDERelated Search:

beta-Sitosterol Artemether beta-Eudesmol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one MOSLOFLAVONE 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one hydroxygenkwanin Hydroxyecdysone alpha-Terpineol alpha-Cyperone 5-hydroxy-2-pyrrolidone L-Proline Nicotine Methyl L-pyroglutamate

  • (1'S,2'S)-NICOTINE 1'-OXIDE
  • (1'S,2'S)-NICOTINE 1'-OXIDE AND (1'R,2'S)-NICOTINE 1'-OXIDE
  • (1'S,2'S)-TRANS-NICOTINE 1'-OXIDE
  • (1S,2S)-syn-Nicotine N'-oxide
  • (1'S,2'S)-trans-Nicotine-1'-N-oxide
  • (1S-cis)-3-(1-Methyl-1-oxido-2-pyrrolidinyl)pyridine
  • (1S-cis)-3-(1-Methyl-2-pyrrolidinyl)pyridine N-Oxide
  • 3-[(1S,2S)-1-Methyl-1-oxido-2-pyrrolidinyl] pyridine
  • 3-[(1S,2S)-1-Methyl-1-oxido-2-pyrrolidinyl]pyridine
  • Nicotine-cis-N-oxide
  • Nicotine Impurity 1
  • S,2&rsquo
  • S)-Nicotine-1&rsquo
  • Pyridine, 3-[(1S,2S)-1-methyl-1-oxido-2-pyrrolidinyl]-
  • 3-[(1S,2S)-1-Methyl-1-oxido-2-pyrrolidinyl]
  • (1S,2S)-1-Methyl-2-(pyridin-3-yl)pyrrolidin-1-ium-1-olate
  • (1's2's)-Nicotine-N'-oxide
  • 3-[(1S,2S)-1-Methyl-1-oxidopyrrolidin-2-yl]pyridine
  • trans-Nicotine EP Impurity E (trans-Nicotine-1′-oxide)
  • Nicotine 1'-N-oxide
  • 51095-86-4
  • Mutagenesis Research Chemicals
  • Nitric Oxide Reagents
  • Nicotine Derivatives
  • Aromatics
  • Chiral Reagents
  • Heterocycles