ChemicalBook > CAS DataBase List > Levocetirizine dihydrochloride
Levocetirizine dihydrochloride
- Product Name
- Levocetirizine dihydrochloride
- CAS No.
- 130018-87-0
- Chemical Name
- Levocetirizine dihydrochloride
- Synonyms
- DDDB;LevocetrizineHCl;LEVOCETIRIZINE HCL;Levocetirizine HCI;LEVOCETIRIZINE 2HCL;Levocitirizine 2HCL;LEVOCETIRIZINE DIHCL;(R)-Cetirizine DiHCl;Xyzal Dihydrochloride;(R)-Form dihydrochloride
- CBNumber
- CB9135031
- Molecular Formula
- C21H27Cl3N2O3
- Formula Weight
- 461.81
- MOL File
- 130018-87-0.mol
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Levocetirizine dihydrochloride Property
- Melting point:
- 215-220°C
- alpha
- D25 -12.79° (c = 1 in water)
- storage temp.
- room temp
- solubility
- H2O: ≥23mg/mL
- form
- powder
- color
- White to Almost white
- Merck
- 14,2022
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 130018-87-0(CAS DataBase Reference)
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- L7795
- Product name
- Levocetirizine dihydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $97.2
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- L7795
- Product name
- Levocetirizine dihydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $376
- Updated
- 2024/03/01
TCI Chemical
- Product number
- L0264
- Product name
- Levocetirizine Dihydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $101
- Updated
- 2024/03/01
TCI Chemical
- Product number
- L0264
- Product name
- Levocetirizine Dihydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $304
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 23992
- Product name
- (R)-Cetirizine (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $68
- Updated
- 2024/03/01
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Levocetirizine dihydrochloride Chemical Properties,Usage,Production
Uses
Anti Histaminic
Uses
Levocetirizine dihydrochloride has been used as standard in the thin layer chromatography optimization and in preparation of racemic cetirizine standard for subcritical fluid chromatography-tandem mass spectrometry analysis.
General Description
Levocetirizine dihydrochloride,(R)-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl] ethoxy] acetic acid dihydrochloride, (Xyzal) is awhite, crystalline powder and is water soluble. ThisR-enantiomer is has a 30-fold higher affinity than the S-enantiomer,and dissociates more slowly from H1-receptors.Pharmacologically, it displays the same receptor and CNSselecitivity profile as the racemate, cetirizine,and thus the same therapeutic advantages. Levocetirizine isindicated for the relief of symptoms associated with allergicrhinitis (seasonal and perennial) in adults and children 6 yearsof age and older and for the treatment of the uncomplicatedskin manifestations of chronic idiopathic urticaria in adultsand children 6 years of age and older. Its pharmacokineticsand clearance profile are essentially the same as the racemate,cetirizine .
Biochem/physiol Actions
Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.
Levocetirizine dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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Levocetirizine dihydrochloride Suppliers
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- 44-20819178-90 02081917890
- Fax
- (0)2080432064
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View Lastest Price from Levocetirizine dihydrochloride manufacturers
Hebei Zhuanglai Chemical Trading Co.,Ltd
- Product
- Levocetirizine dihydrochloride 130018-87-0
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-04-24
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Levocetirizine dihydrochloride 130018-87-0
- Price
- US $0.00/Kg/Bag
- Min. Order
- 1KG
- Purity
- 98.0%~102.0%; USP41
- Supply Ability
- 1500kg/month
- Release date
- 2021-06-03
Hebei Yanxi Chemical Co., Ltd.
- Product
- Levocetirizine dihydrochloride 130018-87-0
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2023-09-19
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