kazinol B
- Product Name
- kazinol B
- CAS No.
- 99624-27-8
- Chemical Name
- kazinol B
- Synonyms
- kazinol B;Aids096026;Aids-096026;6-[(2S)-7-hydroxy-3,4-dihydro-2H-chromen-2-yl]-2,2-dimethyl-7-(3-methylbut-2-enyl)chromen-8-ol;[2,6'-Bi-2H-1-benzopyran]-7,8'-diol, 3,4-dihydro-2',2'-dimethyl-7'-(3-methyl-2-buten-1-yl)-, (2S)-
- CBNumber
- CB91360139
- Molecular Formula
- C25H28O4
- Formula Weight
- 392.49
- MOL File
- 99624-27-8.mol
kazinol B Property
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- InChI
- InChI=1S/C25H28O4/c1-15(2)5-9-19-20(13-17-11-12-25(3,4)29-24(17)23(19)27)21-10-7-16-6-8-18(26)14-22(16)28-21/h5-6,8,11-14,21,26-27H,7,9-10H2,1-4H3/t21-/m0/s1
- InChIKey
- QSCBHDIGHKHWKC-NRFANRHFSA-N
- SMILES
- [C@H]1(C2C=C3C(=C(O)C=2C/C=C(/C)\C)OC(C)(C)C=C3)OC2=CC(O)=CC=C2CC1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FK159345
- Product name
- Kazinol B
- Packaging
- 1mg
- Price
- $300
- Updated
- 2021/12/16
- Product number
- FK159345
- Product name
- Kazinol B
- Packaging
- 2mg
- Price
- $500
- Updated
- 2021/12/16
- Product number
- W2781
- Product name
- KazinolB
- Packaging
- 2mg
- Price
- $725
- Updated
- 2021/12/16
- Product number
- FK159345
- Product name
- Kazinol B
- Packaging
- 5mg
- Price
- $1000
- Updated
- 2021/12/16
- Product number
- FK159345
- Product name
- Kazinol B
- Packaging
- 10mg
- Price
- $1500
- Updated
- 2021/12/16
kazinol B Chemical Properties,Usage,Production
Uses
Kazinol B, a prenylated flavan with a dimethyl pyrane ring, is an inhibitor of nitric oxide (NO) production. Kazinol B improves insulin sensitivity by enhancing glucose uptake via the insulin-Akt signaling pathway and AMPK activation. Kazinol B has the potential for diabetes mellitus research[1][2].
target
Calcium Channel | Sodium Channel | ATPase | NOS | PI3K | PKC | p38MAPK | PPAR | GLUT | Akt | AMPK
IC 50
AMPK
References
[1] Hyejin Lee, et al. Kazinol B from Broussonetia kazinoki improves insulin sensitivity via Akt and AMPK activation in 3T3-L1 adipocytes. Fitoterapia. 2016 Jul;112:90-6. DOI:10.1016/j.fitote.2016.05.006
[2] Jae-Ha Ryu, et al. Fitoterapia. 2003 Jun;74(4):350-4.Inhibition of nitric oxide production on LPS-activated macrophages by kazinol B from Broussonetia kazinoki. DOI:10.1016/s0367-326x(03)00062-5
kazinol B Preparation Products And Raw materials
Raw materials
Preparation Products
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