ChemicalBook > CAS DataBase List > Ropinirole

Ropinirole

Product Name
Ropinirole
CAS No.
91374-21-9
Chemical Name
Ropinirole
Synonyms
Ropinirole base;SKF-101468;ROPINIROLE;Ropinirolum;ROPINIROLE 99%;RSYYRopinirole;Unii-030pyr8953;SKF-101468A：ReQuip;Ropinirole USP/EP/BP;Ropinirole Impurity 22
CBNumber
CB9137570
Molecular Formula
C16H24N2O
Formula Weight
260.37
MOL File
91374-21-9.mol
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Ropinirole Property

Melting point:
243-250°C
Boiling point:
410.5±45.0 °C(Predicted)
Density 
1.040±0.06 g/cm3(Predicted)
pka
14.17±0.20(Predicted)
CAS DataBase Reference
91374-21-9(CAS DataBase Reference)
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Safety

Hazardous Substances Data
91374-21-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris
Product number
3680
Product name
Ropinirole
Purity
≥99%(HPLC)
Packaging
10
Price
$87
Updated
2021/12/16
Tocris
Product number
3680
Product name
Ropinirole
Purity
≥99%(HPLC)
Packaging
50
Price
$363
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004095
Product name
ROPINIROLE
Purity
95.00%
Packaging
10MG
Price
$612.44
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D34162
Product name
Ropinirole-d14 HCl
Packaging
1mg
Price
$625
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004095
Product name
ROPINIROLE
Purity
95.00%
Packaging
50MG
Price
$823.46
Updated
2021/12/16
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Ropinirole Chemical Properties,Usage,Production

Uses

Antiparkinsonian (D2receptor agonist).

Definition

ChEBI: Ropinirole is a member of indolones and a tertiary amine. It has a role as a dopamine agonist, an antiparkinson drug, a central nervous system drug and an antidyskinesia agent.

brand name

Requip (GlaxoSmithKline).

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 1533, 1985 DOI: 10.1021/jm00148a028

Clinical Use


Anti-Parkinson agent
Restless legs syndrome (RLS)

Drug interactions

Potentially hazardous interactions with other drugs
Antipsychotics: antagonism of anti-Parkinsonian effect - avoid.
Metoclopramide: antagonism of anti-Parkinsonian effect - avoid.
Oestrogens: concentration increased.

Metabolism

Ropinirole is hepatically metabolised by the cytochrome P450 enzyme, CYP1A2, and excreted in the urine as inactive metabolites.

Ropinirole Preparation Products And Raw materials

Raw materials

Tetrazole Indole

Preparation Products

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Ropinirole Suppliers

Canada 2 China 116 Europe 2 Germany 1 India 10 The Netherlands 1 United Kingdom 3 United States 22 Global 157
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
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70
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
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United States
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AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
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58
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
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58
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19885
Advantage
58
Acanthus Research
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--
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Email
inquiries@acanthusresearch.com
Country
United States
ProdList
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50
EJY Tech, Inc.
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Country
United States
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AlliChem, LLC
Tel
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Email
sales@allichemllc.com
Country
United States
ProdList
6516
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60
Cerilliant Corporation
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Email
techserv@cerilliant.com
Country
United States
ProdList
1629
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CacheSyn Inc.
Tel
--
Fax
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Email
info@cachesyn.com
Country
United States
ProdList
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50
ACIC Fine Chemicals Inc.
Tel
--
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Email
sales@acic.com
Country
United States
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Beta Pharma, Inc.
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sales@betapharma.com
Country
United States
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Waterstone Technology, LLC
Tel
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Email
sales@waterstonetech.com
Country
United States
ProdList
6786
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30
HONEST JOY HOLDINGS LIMITED
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Email
sales@honestjoy.cn
Country
United States
ProdList
6675
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3B Scientific Corporation
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sales@3bsc.com
Country
United States
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APAC Pharmaceutical, LLC
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United States
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SynFine Research
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research@synfine.com
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United States
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LKT Laboratories, Inc.
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United States
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SST Corporation
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United States
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QVENTAS INC.
Tel
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Email
mike@qventas.com
Country
United States
ProdList
383
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American Custom Chemicals Corporation
Tel
--
Fax
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Email
sales@acccorporation.com
Country
United States
ProdList
6820
Advantage
51
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View Lastest Price from Ropinirole manufacturers

Binzhou Lista Trading Limited
Product
Ropinirole 91374-21-9
Price
US $90.00-80.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
2000kg
Release date
2024-08-12
Hebei Mingeng Biotechnology Co., Ltd
Product
Ropinirole 91374-21-9
Price
US $200.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg/Month
Release date
2022-11-27
Shijiazhuang Gantuo Biotechnology Co., Ltd
Product
Ropinirole 91374-21-9
Price
US $100.00/mg
Min. Order
25mg
Purity
99%
Supply Ability
1000g
Release date
2023-03-10

91374-21-9, RopiniroleRelated Search:

Tetraethylammonium hydroxide cis-Octahydro-isoindole Nile Red 1-(2,6-Dichlorophenyl)indolin-2-one ROPINIROLE HYDROCHLORIDE,ROPINIROLE HCL Ropinirole Intermediate 3 Ropinirole Intermediate 6 4-(2-BroMoethyl)-1,3-dihydro-2H-indolin-2-one Ropinirole Intermediate 1 2-Butanone Ropinirole Intermediate 5 ROPINIROLE-D3, HYDROCHLORIDE 3-Oxo Ropinirole (Ropinirole Impurity C),Ropinirole Impurity C N-Despropyl Ropinirole-d3 Discontinued see product # D297382,N-Despropyl Ropinirole-d3 N-PROPYL-D7-AMINE N-Despropyl Ropinirole Discontinued see product # D297380,N-DESPROPYL ROPINIROLE DI-N-PROPYL-1,1,2,2,3,3,3-D7-AMINE (MONO-PROPYL-D7) Ropinirole

  • ROPINIROLE
  • 4-(2-dipropylaminoethyl)-1,3-dihydroindol-2-one
  • ROPINIROLE: ROPINIROLE HYDROCHLORIDE
  • ROPINIROLE INTERMEIDATES:
  • ROPINIROLE 99%
  • 4-[2-(Dipropylamino)ethyl]-1，3-dihydrcr2H-indol-2-one
  • SKF-101468
  • SKF-101468A：ReQuip
  • 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one
  • 4-[2-(Dipropylamino)ethyl]indoline-2-one
  • 2H-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-
  • 91374-20-8 (Hydrochloride)
  • Ropinirol [inn-spanish]
  • Ropinirolum
  • Ropinirolum [inn-latin]
  • Unii-030pyr8953
  • Ropinirole base
  • Ropinirole(Hydrochloride form)
  • (3S)-3-bromo-2-oxobutanoic acid
  • Ropinirole USP/EP/BP
  • Ropinirole Impurity 22
  • Ropinirole Impurity 23
  • Ropinirole Impurity 24
  • 4-(2-(Dipropylamino)ethyl)indolin-2-one
  • Ropinirole (SKF-101468)
  • RSYYRopinirole
  • RSYYIbrutinib Impurity 141
  • 91374-21-9
  • 91374-58-8
  • C16H24N2O
  • API
  • ACTIVE PHARMACEUTICAL INGREDIENTS
  • Pharmaceutical material and intermeidates
  • Antiparkinsonian