ChemicalBook > CAS DataBase List > PVM/MA

PVM/MA

Product Name
PVM/MA
CAS No.
1644545-52-7
Chemical Name
PVM/MA
Synonyms
E7386;AG881;AG081;HS-01;E-7386;PVM/MA;AG-881;s-22611;FF10101;CS-2621
CBNumber
CB91403717
Molecular Formula
C14H13ClF6N6
Formula Weight
414.74
MOL File
1644545-52-7.mol
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PVM/MA Property

Boiling point:
467.5±55.0 °C(Predicted)
Density 
1.491±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
form 
A crystalline solid
pka
1.49±0.41(Predicted)
color 
Light yellow to light brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28462
Product name
Vorasidenib
Packaging
1mg
Price
$110
Updated
2024/03/01
Cayman Chemical
Product number
28462
Product name
Vorasidenib
Packaging
10mg
Price
$757
Updated
2024/03/01
Cayman Chemical
Product number
28462
Product name
Vorasidenib
Packaging
5mg
Price
$433
Updated
2024/03/01
ChemScene
Product number
CS-8033
Product name
Vorasidenib
Purity
99.87%
Packaging
2mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-8033
Product name
Vorasidenib
Purity
99.87%
Packaging
5mg
Price
$150
Updated
2021/12/16
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PVM/MA Chemical Properties,Usage,Production

Uses

PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.

Synthesis

Maleic anhydride (MA) was added to a solvent mixture of cyclohexane and ethyl acetate in a polymerizer equipped with an agitator, a reflux condenser, and an inner temperature-controlling device. The polymerizer was purged of air and filled with nitrogen. The solution was heated to 70 °C, and then an initiator solution (lauroyl peroxide dissolved in ethyl acetate) and Methyl vinyl ether (MVE) were added to the polymerizer in a dropwise manner. A slurry was obtained, which was filtered and dried under a vacuum to obtain a white powdery copolymer.

PVM/MA Preparation Products And Raw materials

Raw materials

Preparation Products

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PVM/MA Suppliers

Shanghai Aocheng Biological Technology Co., Ltd.
Tel
13917627064
Fax
-qq:56229367
Email
56229367@qq.com
Country
China
ProdList
577
Advantage
58
Wuhan Shanhai Zhihe Biotechnology Co., Ltd.
Tel
17771424646
Email
shoubull@126.com
Country
China
ProdList
969
Advantage
58
Shanghai Hope Chem Co., Ltd.,
Tel
+21-18501659228 18501659228
Fax
sales@hope-chem.com
Email
info@hope-chem.com
Country
China
ProdList
481
Advantage
55
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 17702719238
Email
sales@sun-shinechem.com
Country
China
ProdList
976
Advantage
64
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4512
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
4601
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
028-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
6268
Advantage
58
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View Lastest Price from PVM/MA manufacturers

Wuhan Nutra Biotechnology Co.,Ltd
Product
Vorasidenib;AG-881 1644545-52-7
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
100kgs
Release date
2021-05-24

1644545-52-7, PVM/MARelated Search:


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