ChemicalBook > CAS DataBase List > 4-Iodo-1,2-dimethylbenzene

4-Iodo-1,2-dimethylbenzene

Product Name: 4-Iodo-1,2-dimethylbenzene
CAS No.: 31599-61-8
Chemical Name: 4-Iodo-1,2-dimethylbenzene
Synonyms: 4-IODO-2-XYLENE;4-IODO-O-XYLENE;4-Iodo-o-xylene>4-Iodo-1,2-dimethylb;4-Iodo-o-xylene, 98+%;3,4-DIMETHYLIODOBENZENE;3,4-Dimethjyliodobenzene;3,4-Dimethylphenyl iodide;4-IODO-1,2-DIMETHYLBENZENE;3,4-DIMETHYL-1-IODOBENZENE
CBNumber: CB9143469
Molecular Formula: C8H9I
Formula Weight: 232.06
MOL File: 31599-61-8.mol

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4-Iodo-1,2-dimethylbenzene Property

Melting point:: -2.9°C (estimate)
Boiling point:: 106-108 °C13 mm Hg(lit.)
Density: 1.633 g/mL at 25 °C(lit.)
refractive index: n20/D 1.603(lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: clear liquid
color: Colorless to Brown
Sensitive: Light Sensitive
BRN: 1905729
InChI: InChI=1S/C8H9I/c1-6-3-4-8(9)5-7(6)2/h3-5H,1-2H3
InChIKey: CSFRCLYFVINMBZ-UHFFFAOYSA-N
SMILES: C1(C)=CC=C(I)C=C1C
CAS DataBase Reference: 31599-61-8(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, 4-iodo-1,2-dimethyl-(31599-61-8)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29039990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: I0560
Product name: 4-Iodo-o-xylene
Packaging: 25G
Price: $104
Updated: 2025/07/31

TRC

Product number: I705510
Product name: 4-Iodo-1,2-dimethylbenzene
Packaging: 10g
Price: $75
Updated: 2021/12/16

Oakwood

Product number: 004948
Product name: 4-Iodo-o-xylene
Purity: 98%
Packaging: 1g
Price: $10
Updated: 2021/12/16

Matrix Scientific

Product number: 006559
Product name: 4-Iodo-o-xylene
Packaging: 5g
Price: $11
Updated: 2021/12/16

AK Scientific

Product number: 3429AB
Product name: 4-Iodo-1,2-dimethylbenzene
Packaging: 5g
Price: $14
Updated: 2021/12/16

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4-Iodo-1,2-dimethylbenzene Chemical Properties,Usage,Production

Chemical Properties

clear yellow to red-brown liquid

Uses

1-Iodo-3,4-dimethylbenzene (4-iodo-o-xylene, 3,4-dimethyliodobenzene) may be used in the synthesis of the following:

3-arylacrylamide
3,3-diaryl substituted acrylamide
3-arylpropylamine
di-tert-butyl 1-(3,4-dimethylphenyl)hydrazine-1,2-dicarboxylate
2,3,7,8-tetramethyldibenzofuran
N-(3-(3,4-Dimethylphenyl)-2-phthalimidopropionyl)-2-methylthioaniline

General Description

1-Iodo-3,4-dimethylbenzene (4-iodo-o-xylene, 3,4-dimethyliodobenzene) is an aryl halide. Its synthesis, NMR and IR spectra has been reported. Its nitration reaction and copper catalyzed trifluoromethylation reaction has been studied.

Synthesis

95-47-6

31599-61-8

GENERAL STEPS: To a solution of 1,2-dimethylbenzene (o-xylene, 0.106 g, 1 mmol) in acetonitrile (10 mL) was sequentially added iodine (1 mmol, 0.126 g) and polymer-loaded periodate (0.6 g, 1.05 mmol). The reaction mixture was stirred at 40 °C for 1 hour. The progress of the reaction was monitored by thin layer chromatography (TLC) and the unfolding agent was a solvent mixture of ethyl acetate and hexane (1:9, v/v). After completion of the reaction, the mixture was cooled to room temperature and filtered. Excess iodine in the filtrate was removed by adding sodium bisulfite solution (1 M) dropwise. The organic layer was separated, dried with anhydrous magnesium sulfate, filtered and evaporated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography, the eluent being a solvent mixture of hexane and ethyl acetate. The final product was 3,4-dimethyl iodobenzene in 95% isolated yield with a boiling point of 235 °C (literature value: 234 °C).

References

[1] Bulletin of the Chemical Society of Ethiopia, 2014, vol. 28, # 2, p. 305 - 308
[2] Tetrahedron Letters, 2011, vol. 52, # 18, p. 2413 - 2414
[3] Advanced Synthesis and Catalysis, 2005, vol. 347, # 15, p. 1925 - 1928
[4] Patent: EP1595862, 2005, A1. Location in patent: Page/Page column 9
[5] European Journal of Organic Chemistry, 2017, vol. 2017, # 22, p. 3234 - 3239

4-Iodo-1,2-dimethylbenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Iodo-1,2-dimethylbenzene manufacturers

Speranza Chemical Co., Ltd.

Product: 4-iodo-1,2-dimethylbenzene 31599-61-8
Price: US $930.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 300MT/year
Release date: 2019-12-24

Shenzhen Nexcon Pharmatechs Ltd.

Product: 4-Iodo-1,2-dimethylbenzene 31599-61-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 2000
Release date: 2025-04-17

Henan Aochuang Chemical Co.,Ltd.

Product: 4-Iodo-1,2-dimethylbenzene 31599-61-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

31599-61-8, 4-Iodo-1,2-dimethylbenzeneRelated Search:

Dimethyl ether Dimethyl sulfoxide 1,2-Diiodobenzene N,N-Dimethylformamide Dimethyl fumarate Poly(dimethylsiloxane) Methyl 2-iodobenzoate Xylene 1,4-Diiodobenzene XYLENE CYANOL FF Bromobenzene Musk xylene ETHANE Dimethyl phthalate Chlorobenzene (Diacetoxyiodo)benzene 1,3-Dimethylbarbituric acid Dimethyl sulfide

1,2-DIMETHYL-4-IODOBENZENE, 98+%

4-Iodo-o-xylene, 98+%

3,4-Dimethjyliodobenzene

3,4-Dimethylphenyl iodide

4-Iodo-1,2-dimethylb

1-IODO-3,4-DIMETHYLBENZENE

1,2-DIMETHYL-4-IODOBENZENE

3,4-DIMETHYL-1-IODOBENZENE

3,4-DIMETHYLIODOBENZENE

4-IODO-2-XYLENE

4-IODO-1,2-DIMETHYLBENZENE

4-IODO-O-XYLENE

4-Iodo-o-xylene&gt

Benzene, 4-iodo-1,2-dimethyl-

4-IODO-o-XYLENE Or 1-IODO-3,4-DIMETHYLBENZENE

3,4-dimethyliodobenzene (4-iodo-xylene)

1-Iodo-3,4-dimethylbenzene, 96%

31599-61-8

3159-61-8

Building Blocks

Aryl

Organic Building Blocks

Halogenated Hydrocarbons

HALOGEN

Aryl

Building Blocks

Chemical Synthesis

Halogenated Hydrocarbons

Organic Building Blocks

Iodine Compounds

Aromatic Hydrocarbons (substituted) & Derivatives