ethyl 3-amino-3-phenylpropanoate
Uses- Product Name
- ethyl 3-amino-3-phenylpropanoate
- CAS No.
- 6335-76-8
- Chemical Name
- ethyl 3-amino-3-phenylpropanoate
- Synonyms
- NSC 38811;-propionic acid ethyL;ethyl 3-amino-3-phenylpropanoate;Ethyl 3-amino-3-phenylpropionate;Ethyl 3-amino-3-phenylpropionate 95+%;ETHYL-3-AMINO-3-PHENYLPROPANOATEhyHCL;3-Amino-3-phenylpropanoic acid ethyl ester;beta-Aminobenzenepropanoic acid ethyl ester;Benzenepropanoic acid, β-amino-, ethyl ester;Benzenepropanoic acid, b-aMino-, ethyl ester
- CBNumber
- CB91791232
- Molecular Formula
- C11H15NO2
- Formula Weight
- 193.24
- MOL File
- 6335-76-8.mol
ethyl 3-amino-3-phenylpropanoate Property
- Melting point:
- 111-112℃ (water ethanol )
- Boiling point:
- 155 °C(Press: 13 Torr)
- Density
- 1.075±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 7.75±0.10(Predicted)
Safety
- Risk Statements
- 22
- HS Code
- 2922390090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- E940243
- Product name
- Ethyl3-amino-3-phenylpropanoate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- E940243
- Product name
- Ethyl3-amino-3-phenylpropanoate
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- OR300757
- Product name
- Ethyl3-amino-3-phenylpropionate
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 126128
- Product name
- Ethyl3-amino-3-phenyl-propanoatehydrochloride
- Purity
- >95%
- Packaging
- 500mg
- Price
- $166
- Updated
- 2021/12/16
- Product number
- 126128
- Product name
- Ethyl3-amino-3-phenyl-propanoatehydrochloride
- Purity
- >95%
- Packaging
- 1g
- Price
- $223
- Updated
- 2021/12/16
ethyl 3-amino-3-phenylpropanoate Chemical Properties,Usage,Production
Uses
Ethyl 3-amino-3-phenylpropionate is a β-amino acid derivative that is widely used in drug synthesis.
Synthesis
64-17-5
141-82-2
100-52-7
6335-76-8
To a 500 mL three-necked flask was added 50 mL of ethanol, 9.3 g of malonic acid and 18.2 g of ammonium acetate, heated to 50°C, and 10.0 g of benzaldehyde was slowly added dropwise. After the dropwise addition, the reaction was heated to reflux. After the reaction was completed, the mixture was cooled to below 10°C and 40 g of thionyl chloride was slowly added dropwise. The mixture was heated to reflux for 16 hours, followed by distillation to remove ethanol. To the residue 50 mL of dichloromethane was added and the pH was adjusted to 6-7 with 5 N NaOH solution. the organic layer was separated and the aqueous layer was extracted with dichloromethane. The organic layers were combined and concentrated to give 14.2 g of colorless oily material, which was analyzed by HPLC for 98% purity and 78% yield.
References
[1] Patent: CN106083624, 2016, A. Location in patent: Paragraph 0019
ethyl 3-amino-3-phenylpropanoate Preparation Products And Raw materials
Raw materials
Preparation Products
ethyl 3-amino-3-phenylpropanoate Suppliers
- Tel
- --
- Fax
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- contact@achemica.com
- Country
- Switzerland
- ProdList
- 6155
- Advantage
- 50
View Lastest Price from ethyl 3-amino-3-phenylpropanoate manufacturers
- Product
- Ethyl 3-amino-3-phenylpropanoate 6335-76-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-19
- Product
- ethyl 3-amino-3-phenylpropanoate 6335-76-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 85.0-99.8%
- Supply Ability
- 200kgs
- Release date
- 2020-01-10