ChemicalBook > CAS DataBase List > 4-Hydroxy-3-methoxymandelic acid

4-Hydroxy-3-methoxymandelic acid

Product Name: 4-Hydroxy-3-methoxymandelic acid
CAS No.: 55-10-7
Chemical Name: 4-Hydroxy-3-methoxymandelic acid
Synonyms: VMA;Vanilmandelic;VANILMANDELIC ACID;VANILLOMANDELIC ACID;Vanilinmandelic Acid;VANILLYLMANDELIC ACID;Vanillinmandelic acid;DL-VANILLOMANDELIC ACID;VANILLYLMANDELIC ACID 99%;HYDROXYMETHOXYMANDELICACID
CBNumber: CB9212402
Molecular Formula: C9H10O5
Formula Weight: 198.17
MOL File: 55-10-7.mol

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4-Hydroxy-3-methoxymandelic acid Property

Melting point:: 132-134 °C (dec.)(lit.)
Boiling point:: 255.48°C (rough estimate)
Density: 1.2539 (rough estimate)
refractive index: 1.4570 (estimate)
FEMA: 4660 | HYDROXY(4-HYDROXY-3-METHOXYPHENYL)ACETIC ACID
storage temp.: 2-8°C
solubility: H₂O: ~50 mg/mL
pka: 3.42±0.10(Predicted)
form: powder
color: white to off-white
Water Solubility: freely soluble
JECFA Number: 2020
Merck: 14,9933
BRN: 2213227
LogP: -0.212 (est)
EPA Substance Registry System: Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy- (55-10-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
F: 10-23
HS Code: 29181998

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H0131
Product name: DL-4-Hydroxy-3-methoxymandelic acid
Purity: ≥98% (HPLC), powder
Packaging: 100MG
Price: $37.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: H0131
Product name: DL-4-Hydroxy-3-methoxymandelic acid
Purity: ≥98% (HPLC), powder
Packaging: 250MG
Price: $59.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: H0131
Product name: DL-4-Hydroxy-3-methoxymandelic acid
Purity: ≥98% (HPLC), powder
Packaging: 500MG
Price: $97.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: H0131
Product name: DL-4-Hydroxy-3-methoxymandelic acid
Purity: ≥98% (HPLC), powder
Packaging: 1G
Price: $168
Updated: 2025/07/31

Sigma-Aldrich

Product number: H0131
Product name: DL-4-Hydroxy-3-methoxymandelic acid
Purity: ≥98% (HPLC), powder
Packaging: 5G
Price: $603
Updated: 2025/07/31

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4-Hydroxy-3-methoxymandelic acid Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A metabolite of catecholamines.

Definition

ChEBI: An aromatic ether that is the 3-O-methyl ether of 3,4-dihydroxymandelic acid.

Biochem/physiol Actions

Epinephrine and norepineprine metabolite.

in vivo

Vanillylmandelic acid (intra-arterial injection over 1 min; 1, 10 and 100 mg/kg; the 60 min-observation period) produces a significant difference between vanillylmandelic acid groups and controls. Vanillylmandelic acid decreases the heart rate by 17.5%, 17.9% and 18.9% after 1, 10 and 100 mg/kg, respectively. Mean blood pressure is decreased by 13.5% in control animals as compared to 37%, 23% and 26% after 1, 10 and 100 mg/kg, respectively, in wistar rats^[1].

IC 50

Human Endogenous Metabolite; Microbial Metabolite

4-Hydroxy-3-methoxymandelic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxy-3-methoxymandelic acid Suppliers

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View Lastest Price from 4-Hydroxy-3-methoxymandelic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Hydroxy-3-methoxymandelic acid 55-10-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-25

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: Vanillyl mandelic acid 55-10-7
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2021-09-24

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: Vanillyl mandelic acid 55-10-7
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10kg
Release date: 2021-09-24

55-10-7, 4-Hydroxy-3-methoxymandelic acidRelated Search:

DL-Mandelic acid Hyaluronic acid Malic acid Mandelic acid 4-Chloromandelic acid CHLOROPHOSPHONAZO III Ethyl 2-(Chlorosulfonyl)acetate Folic acid (Trifluoromethoxy)benzene (+/-)-VANILMANDELIC-D3 ACID DL-4-HYDROXY-3-METHOXYMANDELIC-2-D1 ACID Vanilmandelic-[13C,d3] Acid 4-Hydroxyphenylacetic acid (S)-(+)-Mandelic acid Anisole Citric acid Ascoric Acid DL-4-HYDROXY-3-METHOXYMANDELIC ACID

alpha,4-dihydroxy-3-methoxy-benzeneaceticaci

HYDROXY-3-METHOXYMANDELIC ACID, D,L-4-

DL-4-HYDROXY-3-METHOXYMANDELIC ACID

DL-3-METHOXY-4-HYDROXYMANDELIC ACID

DL-VANILLOMANDELIC ACID

ALPHA,4-DIHYDROXY-3-METHOXYBENZENEACETIC ACID

VANILMANDELIC ACID

VANILLYLMANDELIC ACID

VANILLOMANDELIC ACID

VMA

(+/-)-4-HYDROXY-3-METHOXYMANDELIC ACID

4-HYDROXY-3-METHOXYMANDELIC ACID

3-METHOXY-4-HYDROXY MANDELIC ACID

VMA, 98% (VANILLOMANDELIC ACID)

VANILLYLMANDELIC ACID 99%

Benzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy-

4-HYDROXY-3-METHOXYMANDELICACID,REAGENT

(2S)-2-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)acetic acid

HYDROXYMETHOXYMANDELICACID

3-METHOXY-4-HYDROXYMANDELIC ACID 99%

Vanilinmandelic Acid

α,4-Dihydroxy-3-methoxybenzeneacetic acid

α,4-Dihydroxy-3-methoxybenzeneacetic acid, Vanillomandelic acid, Vanillylmandelic acid, Vanilmandelic acid, VMA

2-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetic acid

Vanillinmandelic acid

4-Hydroxy-3-methoxymandelic acid,99%

4-hydroxy 3-methoxy mandelic acid(VMA)

4-Hydroxy-3-MethoxyMandelic acid, 99% 1GR

Adrenaline Related Compound 2

DL-4-Hydroxy-3-methoxymandelicAcid&gt

Benzeneacetic acid, α,4-dihydroxy-3-methoxy-

(2S)-2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)acetate

Vanilmandelic

4-Hydroxy-3-methoxymandelic Acid in Methanol

Vanillylmandelic acid, 10 mM in DMSO

<sc>DL</sc>-4-Hydroxy-3-methoxymandelic acid

(±)-4-Hydroxy-3-methoxymandelic acid solution

55-10-7

1955-10-7

BioChemical

Building Blocks

Catecholamine

Carboxylic Acids

Carbonyl Compounds

Metabolomics

Metabolic Pathways

Metabolites and Cofactors on the Metabolic Pathways Chart

Organic Building Blocks

Cofactor

Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

Aromatics Compounds

Aromatics