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HL 725

Product Name
HL 725
CAS No.
78416-81-6
Chemical Name
HL 725
Synonyms
HL 725;HL 725 HCL;TREQUINSIN;Trequinsin, HCl;TREQUINSIN HYDROCHLORIDE;Riluzole Impurity 13-13C;DTCZZBVPTHVXFA-OSMRDGEFSA-N;TREQUINSIN HYDROCHLORIDE MINIMUM 98%;4,6-trimethylphenyl)imino)--2-((monohydrochloride;Trequinsin, Hydrochloride - CAS 78416-81-6 - Calbiochem
CBNumber
CB9238844
Molecular Formula
C24H28ClN3O3
Formula Weight
441.95
MOL File
78416-81-6.mol
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HL 725 Property

Melting point:
210-211 °C(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
storage temp. 
Desiccate at RT
solubility 
DMSO: 100 mM; Ethanol: 100 mM
form 
Pale yellow solid
color 
Light yellow to yellow
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Safety

WGK Germany 
3
RTECS 
UW7727000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T2057
Product name
Trequinsin hydrochloride
Purity
≥98%
Packaging
10mg
Price
$245.4
Updated
2024/03/01
Sigma-Aldrich
Product number
382425
Product name
Trequinsin, Hydrochloride
Packaging
10mg
Price
$390
Updated
2024/03/01
Cayman Chemical
Product number
17217
Product name
Trequinsin (hydrochloride)
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
17217
Product name
Trequinsin (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$193
Updated
2024/03/01
Cayman Chemical
Product number
17217
Product name
Trequinsin (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$278
Updated
2024/03/01
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HL 725 Chemical Properties,Usage,Production

Uses

Trequinsin Hydrochloride is an ultrapotent inhibitor of phosphodiesterase (PDE) 3.

Uses

PDE inhibitor

Biological Activity

Extremely potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3; IC 50 = 250 pM). Potently inhibits arachidonic acid-induced aggregation of human platelets (IC 50 = 50 pM). Orally active antihypertensive agent; reduces systemic blood pressure in both normotensive and hypertensive animal models.

storage

Desiccate at RT

HL 725 Preparation Products And Raw materials

Raw materials

Preparation Products

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HL 725 Suppliers

China 16 Germany 1 Switzerland 2 United Kingdom 5 United States 18 Global 42
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

78416-81-6, HL 725Related Search:

ZARDAVERINE RO 20-1724 AG 1295 S- (+)-Rolipram ETAZOLATE BRL 50481 Vinpocetine ZAPRINAST ROLIPRAM Cilostazol (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE CILOSTAMIDE EHNA HYDROCHLORIDE 4-[[3,4-(METHYLENEDIOXY)BENZYL]AMINO]-6-CHLOROQUINAZOLINE HL 725 N-2,4-DIMETHYLPHENYL-N'-METHYLFORMAMIDINE N-ETHYLAMINOCARBONYLTYRAMINE N-(3,4-DIMETHOXYBENZYL)UREA

  • 4,6-trimethylphenyl)imino)--2-((monohydrochloride
  • 4h-pyrimido(6,1-a)isoquinolin-4-one,2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl
  • HL 725
  • HL 725 HCL
  • Trequinsin, Hydrochloride - CAS 78416-81-6 - Calbiochem
  • 2,3,6,7-TETRAHYDRO-9,10-DIMETHOXY-3-METHYL-2-[(2,4,6-TRIMETHYLPHENYL)IMINO]-4H-PYRIMIDO[6,1-A]ISOQUINOLIN-4-ONE HYDROCHLORIDE
  • 9,10-DIMETHOXY-2-MESITYLIMINO-3-METHYL-2,3,6,7-TETRAHYDRO-4H-PYRIMIDO-(6,1-A)-ISOQUINOLIN-4-ONE, HCL
  • 9,10-DIMETHOXY-2-MESITYLIMINO-3-METHYL-2,3,6,7-TETRAHYDRO-4H-PYRIMIDO-[6,1A]-ISOQUINOLIN-4-ONE HYDROCHLORIDE
  • TREQUINSIN HYDROCHLORIDE MINIMUM 98%
  • TREQUINSIN
  • TREQUINSIN HYDROCHLORIDE
  • Trequinsin, HCl
  • 4H-Pyrimido(6,1-A)isoquinolin-4-one, 2,3,6,7-tetrahydro-9,10-dimethoxy-3-methyl-2-((2,4,6-trimethylphenyl)imino)-, monohydrochloride
  • 2,3,6,7-Tetrahydro-9,10-dimethoxy-3-methyl-2-[(2,4,6-trimethylphenyl)imino]-4H-pyrimido[6,1-a]isoquinolin-4-onehydrochloride
  • DTCZZBVPTHVXFA-OSMRDGEFSA-N
  • Riluzole Impurity 13-13C
  • 78416-81-6
  • C24H27N3O3HCl
  • C24H27N3O3
  • Cyclic Nucleotide Metabolism
  • G Proteins and Cyclic Nucleotides
  • Phosphodiesterase Inhibitors
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology