5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT

Product Name: 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT
CAS No.: 68792-52-9
Chemical Name: 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT
Synonyms: 5-METHYLTETRAHYDROFOLIC ACID DISODIU;5-METHYLTETRAHYDROFOLIC ACID DISODIUM;5-Methyltetrahydrofolic acid-[13C5] 5MTHF;5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT;5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT USP/EP/BP;5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT ABOUT 90%;5-METHYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID DISODIUM SALT;Sodium 2-(4-(((2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioate;5-Methyltetrahydrofolic acid disodium salt,5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid disodium salt, 5-Methyl-THF
CBNumber: CB9241222
Molecular Formula: C20H23N7Na2O6
Formula Weight: 503.42
MOL File: 68792-52-9.mol

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5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Property

storage temp.: -20°C

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Safety

WGK Germany: 3
F: 10

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M0132
Product name: 5-Methyltetrahydrofolic acid disodium salt
Purity: ≥88% (UV-vis)
Packaging: 5mg
Price: $145
Updated: 2024/03/01

Sigma-Aldrich

Product number: M0132
Product name: 5-Methyltetrahydrofolic acid disodium salt
Purity: ≥88% (UV-vis)
Packaging: 10mg
Price: $250
Updated: 2024/03/01

Sigma-Aldrich

Product number: SRE0010
Product name: 5-Methyltetrahydrofolic acid disodium salt
Purity: ≥88% (UV-vis), Suitable for manufacturing of diagnostic kits and reagents
Packaging: 5mg
Price: $136
Updated: 2024/03/01

Sigma-Aldrich

Product number: SRE0010
Product name: 5-Methyltetrahydrofolic acid disodium salt
Purity: ≥88% (UV-vis), Suitable for manufacturing of diagnostic kits and reagents
Packaging: 10mg
Price: $231
Updated: 2024/03/01

Sigma-Aldrich

Product number: SRE0010
Product name: 5-Methyltetrahydrofolic acid disodium salt
Purity: ≥88% (UV-vis), Suitable for manufacturing of diagnostic kits and reagents
Packaging: 25mg
Price: $487
Updated: 2024/03/01

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5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Chemical Properties,Usage,Production

Uses

5-Methyltetrahydrofolic acid disodium salt (CAS# 68792-52-9) is a folate derivative and the sodium salt form of N-Methyltetrahydrofolic acid (M338145).

Biochem/physiol Actions

5-Methyl-THF acts as both cofactor and substrate in the regeneration of methionine from homocysteine through the action of 5-methyl-THF-homocysteine S-methyltransferase.

Purification Methods

First check the purity by measuring the UV at pH 7.0 (use phosphate buffer), and it should have max at 290nm and min at 245nm with a ratio of A290/A250 of 3.7. This ratio goes down to 1.3 as oxidation to the dihydro derivative occurs. The latter can be reduced back to the tetrahydro compound by reaction with 2-mercaptoethanol at room temperature. If oxidation has occurred, then the compound should be chromatographed on DEAE-cellulose (~0.9 milliequiv/g, in AcOform) in (NH4)2CO3 (1.5 M) and washed with 1M NH4OAc containing 0.01M mercaptoethanol till free from UV absorption and then washed with 0.01M mercaptoethanol. All is done in a nitrogen atmosphere. The reduced folate is then eluted with a gradient between 0.01M mercaptoethanol and 1M NH4OAc containing 0.01M mercaptoethanol, and the fractions with absorption at 290nm are collected. These are evaporated under reduced pressure at 25o, and traces of NH4OAc and H2O are removed at high vacuum/25o (~24-48hours). The residue is dissolved in the minimum volume of 0.01M mercaptoethanol, and an equivalent of NaOH is added to convert the acid to the diNa salt and evaporated to dryness at 25o/high vacuum. The pure product has max 290nm ( 32,000) in pH 7.0 buffer. [Sakami Biochemical Preparations 10 103 1963.]

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Suppliers

China 14 Germany 1 Switzerland 1 United Kingdom 1 United States 5 Global 22

Shanghai Aladdin Bio-Chem Technology Co.,LTD

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View Lastest Price from 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT manufacturers

Dideu Industries Group Limited

Product: 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT 68792-52-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-30

68792-52-9, 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALTRelated Search:

GLUTARIC ACID SODIUM SALT 2,5-Diaminopyrimidine 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE 4,5-DIAMINO-6-HYDROXYPYRIMIDINE HEMISULFATE 2,4-Diamino-6-hydroxypyrimidine 4-Aminohippuric acid 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT P-AMINOHIPPURIC ACID SODIUM SALT 2,4-Diamino-6-hydroxypyrimidine ,98% HIPPURIC ACID SODIUM SALT N-(4-Aminobenzoyl)-DL-glutamic acid Monosodium glutamate 2,4,5-TRIAMINOPYRIMIDINE 4-Amino-N-(2-hydroxyethyl)benzamide HIPPURIC ACID SODIUM SALT L-Tetrahydrofolic Acid Folic acid 4-METHYLAMINO-BENZAMIDE

5-METHYLTETRAHYDROFOLIC ACID DISODIUM

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT ABOUT 90%

5-METHYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID DISODIUM SALT

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT

5-Methyltetrahydrofolic acid disodium salt,5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid disodium salt, 5-Methyl-THF

5-Methyltetrahydrofolic acid-[13C5] 5MTHF

Sodium 2-(4-(((2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioate

5-METHYLTETRAHYDROFOLIC ACID DISODIU

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT USP/EP/BP

68792-52-9

C20H23N7Na2O6

C20H23N7O62Na

Fluorogenic

Cofactors

Enzymes, Inhibitors, and Substrates

Oxidation-Reduction

Biochemicals and Reagents

BioChemical

Activity