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5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT

Product Name
5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT
CAS No.
68792-52-9
Chemical Name
5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT
Synonyms
5-METHYLTETRAHYDROFOLIC ACID DISODIU;5-METHYLTETRAHYDROFOLIC ACID DISODIUM;5-Methyltetrahydrofolic acid-[13C5] 5MTHF;5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT;5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT USP/EP/BP;5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT ABOUT 90%;5-METHYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID DISODIUM SALT;Sodium 2-(4-(((2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioate;5-Methyltetrahydrofolic acid disodium salt,5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid disodium salt, 5-Methyl-THF
CBNumber
CB9241222
Molecular Formula
C20H23N7Na2O6
Formula Weight
503.42
MOL File
68792-52-9.mol
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5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Property

storage temp. 
-20°C
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Safety

WGK Germany 
3
10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M0132
Product name
5-Methyltetrahydrofolic acid disodium salt
Purity
≥88% (UV-vis)
Packaging
5mg
Price
$145
Updated
2024/03/01
Sigma-Aldrich
Product number
M0132
Product name
5-Methyltetrahydrofolic acid disodium salt
Purity
≥88% (UV-vis)
Packaging
10mg
Price
$250
Updated
2024/03/01
Sigma-Aldrich
Product number
SRE0010
Product name
5-Methyltetrahydrofolic acid disodium salt
Purity
≥88% (UV-vis), Suitable for manufacturing of diagnostic kits and reagents
Packaging
5mg
Price
$136
Updated
2024/03/01
Sigma-Aldrich
Product number
SRE0010
Product name
5-Methyltetrahydrofolic acid disodium salt
Purity
≥88% (UV-vis), Suitable for manufacturing of diagnostic kits and reagents
Packaging
10mg
Price
$231
Updated
2024/03/01
Sigma-Aldrich
Product number
SRE0010
Product name
5-Methyltetrahydrofolic acid disodium salt
Purity
≥88% (UV-vis), Suitable for manufacturing of diagnostic kits and reagents
Packaging
25mg
Price
$487
Updated
2024/03/01
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5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Chemical Properties,Usage,Production

Uses

5-Methyltetrahydrofolic acid disodium salt (CAS# 68792-52-9) is a folate derivative and the sodium salt form of N-Methyltetrahydrofolic acid (M338145).

Biochem/physiol Actions

5-Methyl-THF acts as both cofactor and substrate in the regeneration of methionine from homocysteine through the action of 5-methyl-THF-homocysteine S-methyltransferase.

Purification Methods

First check the purity by measuring the UV at pH 7.0 (use phosphate buffer), and it should have max at 290nm and min at 245nm with a ratio of A290/A250 of 3.7. This ratio goes down to 1.3 as oxidation to the dihydro derivative occurs. The latter can be reduced back to the tetrahydro compound by reaction with 2-mercaptoethanol at room temperature. If oxidation has occurred, then the compound should be chromatographed on DEAE-cellulose (~0.9 milliequiv/g, in AcOform) in (NH4)2CO3 (1.5 M) and washed with 1M NH4OAc containing 0.01M mercaptoethanol till free from UV absorption and then washed with 0.01M mercaptoethanol. All is done in a nitrogen atmosphere. The reduced folate is then eluted with a gradient between 0.01M mercaptoethanol and 1M NH4OAc containing 0.01M mercaptoethanol, and the fractions with absorption at 290nm are collected. These are evaporated under reduced pressure at 25o, and traces of NH4OAc and H2O are removed at high vacuum/25o (~24-48hours). The residue is dissolved in the minimum volume of 0.01M mercaptoethanol, and an equivalent of NaOH is added to convert the acid to the diNa salt and evaporated to dryness at 25o/high vacuum. The pure product has max 290nm ( 32,000) in pH 7.0 buffer. [Sakami Biochemical Preparations 10 103 1963.]

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Suppliers

Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-400-6206333 18521732826
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021-50323701
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market@aladdin-e.com
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China
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TianJin Alta Scientific Co., Ltd.
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Sigma-Aldrich
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Aikon International Limited
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Nextpeptide Inc
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Dideu Industries Group Limited
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AFINE CHEMICALS LIMITED
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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18621169109
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China
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Shanghai Yingxin laboratory equipment Co., Ltd
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021-021-59178156 15300768757
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359382369@qq.com
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View Lastest Price from 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT manufacturers

Dideu Industries Group Limited
Product
5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT 68792-52-9
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-30

68792-52-9, 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALTRelated Search:


  • 5-METHYLTETRAHYDROFOLIC ACID DISODIUM
  • 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT ABOUT 90%
  • 5-METHYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID DISODIUM SALT
  • 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT
  • 5-Methyltetrahydrofolic acid disodium salt,5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid disodium salt, 5-Methyl-THF
  • 5-Methyltetrahydrofolic acid-[13C5] 5MTHF
  • Sodium 2-(4-(((2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioate
  • 5-METHYLTETRAHYDROFOLIC ACID DISODIU
  • 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT USP/EP/BP
  • 68792-52-9
  • C20H23N7Na2O6
  • C20H23N7O62Na
  • Fluorogenic
  • Cofactors
  • Enzymes, Inhibitors, and Substrates
  • Oxidation-Reduction
  • Biochemicals and Reagents
  • BioChemical
  • Activity