5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT

Product Name: 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT
CAS No.: 68792-52-9
Chemical Name: 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT
Synonyms: 5-METHYLTETRAHYDROFOLIC ACID DISODIU;5-METHYLTETRAHYDROFOLIC ACID DISODIUM;5-Methyltetrahydrofolic acid-[13C5] 5MTHF;5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT;5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT USP/EP/BP;5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT ABOUT 90%;5-METHYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID DISODIUM SALT;Sodium 2-(4-(((2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioate;5-Methyltetrahydrofolic acid disodium salt,5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid disodium salt, 5-Methyl-THF
CBNumber: CB9241222
Molecular Formula: C20H23N7Na2O6
Formula Weight: 503.42
MOL File: 68792-52-9.mol

More

Less

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Property

storage temp.: -20°C

More

Less

Safety

WGK Germany: 3
F: 10

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M0132
Product name: 5-Methyltetrahydrofolic acid disodium salt
Purity: ≥88% (UV-vis)
Packaging: 5mg
Price: $145
Updated: 2024/03/01

Sigma-Aldrich

Product number: M0132
Product name: 5-Methyltetrahydrofolic acid disodium salt
Purity: ≥88% (UV-vis)
Packaging: 10mg
Price: $250
Updated: 2024/03/01

Sigma-Aldrich

Product number: SRE0010
Product name: 5-Methyltetrahydrofolic acid disodium salt
Purity: ≥88% (UV-vis), Suitable for manufacturing of diagnostic kits and reagents
Packaging: 5mg
Price: $136
Updated: 2024/03/01

Sigma-Aldrich

Product number: SRE0010
Product name: 5-Methyltetrahydrofolic acid disodium salt
Purity: ≥88% (UV-vis), Suitable for manufacturing of diagnostic kits and reagents
Packaging: 10mg
Price: $231
Updated: 2024/03/01

Sigma-Aldrich

Product number: SRE0010
Product name: 5-Methyltetrahydrofolic acid disodium salt
Purity: ≥88% (UV-vis), Suitable for manufacturing of diagnostic kits and reagents
Packaging: 25mg
Price: $487
Updated: 2024/03/01

More

Less

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Chemical Properties,Usage,Production

Uses

5-Methyltetrahydrofolic acid disodium salt (CAS# 68792-52-9) is a folate derivative and the sodium salt form of N-Methyltetrahydrofolic acid (M338145).

Biochem/physiol Actions

5-Methyl-THF acts as both cofactor and substrate in the regeneration of methionine from homocysteine through the action of 5-methyl-THF-homocysteine S-methyltransferase.

Purification Methods

First check the purity by measuring the UV at pH 7.0 (use phosphate buffer), and it should have max at 290nm and min at 245nm with a ratio of A290/A250 of 3.7. This ratio goes down to 1.3 as oxidation to the dihydro derivative occurs. The latter can be reduced back to the tetrahydro compound by reaction with 2-mercaptoethanol at room temperature. If oxidation has occurred, then the compound should be chromatographed on DEAE-cellulose (~0.9 milliequiv/g, in AcOform) in (NH4)2CO3 (1.5 M) and washed with 1M NH4OAc containing 0.01M mercaptoethanol till free from UV absorption and then washed with 0.01M mercaptoethanol. All is done in a nitrogen atmosphere. The reduced folate is then eluted with a gradient between 0.01M mercaptoethanol and 1M NH4OAc containing 0.01M mercaptoethanol, and the fractions with absorption at 290nm are collected. These are evaporated under reduced pressure at 25o, and traces of NH4OAc and H2O are removed at high vacuum/25o (~24-48hours). The residue is dissolved in the minimum volume of 0.01M mercaptoethanol, and an equivalent of NaOH is added to convert the acid to the diNa salt and evaporated to dryness at 25o/high vacuum. The pure product has max 290nm ( 32,000) in pH 7.0 buffer. [Sakami Biochemical Preparations 10 103 1963.]

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT Suppliers

China 14 Germany 1 Switzerland 1 United Kingdom 1 United States 5 Global 22

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

TianJin Alta Scientific Co., Ltd.

Tel: 022-65378550-8551
Fax: +86-022-2532-9655
Email: contact@altascientific.com
Country: China
ProdList: 2773
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15084
Advantage: 58

Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 22883
Advantage: 58

Zhuoer Chemical Co., Ltd

Tel: 02120970332; +8613524231522
Fax: +86-21-58816016
Email: sales@zhuoerchem.com
Country: China
ProdList: 2904
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15354
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Shanghai Yingxin laboratory equipment Co., Ltd

Tel: 021-021-59178156 15300768757
Email: 359382369@qq.com
Country: China
ProdList: 10674
Advantage: 58

Shanghai Guchen Biotechnology Co., LTD

Tel: 021-34675735 19147740836
Email: 1986399151@qq.com
Country: China
ProdList: 9844
Advantage: 58

LEAPCHEM CO., LTD.

Tel: +86-852-30606658
Email: market18@leapchem.com
Country: China
ProdList: 43340
Advantage: 58

Guangzhou WeiBo Chemical Co., Ltd.

Tel: --
Fax: --
Email: weibochem@163.com
Country: China
ProdList: 6187
Advantage: 67

Advanced Technology & Industrial Co., Ltd.

Tel: --
Fax: --
Email: sales@advtechind.com
Country: China
ProdList: 6523
Advantage: 75

More

Less

View Lastest Price from 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT manufacturers

Dideu Industries Group Limited

Product: 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT 68792-52-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-30

68792-52-9, 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALTRelated Search:

GLUTARIC ACID SODIUM SALT 2,5-Diaminopyrimidine 6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE 4,5-DIAMINO-6-HYDROXYPYRIMIDINE HEMISULFATE 2,4-Diamino-6-hydroxypyrimidine 4-Aminohippuric acid 5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT P-AMINOHIPPURIC ACID SODIUM SALT 2,4-Diamino-6-hydroxypyrimidine ,98% HIPPURIC ACID SODIUM SALT N-(4-Aminobenzoyl)-DL-glutamic acid Monosodium glutamate 2,4,5-TRIAMINOPYRIMIDINE 4-Amino-N-(2-hydroxyethyl)benzamide HIPPURIC ACID SODIUM SALT L-Tetrahydrofolic Acid Folic acid 4-METHYLAMINO-BENZAMIDE

5-METHYLTETRAHYDROFOLIC ACID DISODIUM

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT ABOUT 90%

5-METHYL-5,6,7,8-TETRAHYDROPTEROYL-L-GLUTAMIC ACID DISODIUM SALT

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT

5-Methyltetrahydrofolic acid disodium salt,5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid disodium salt, 5-Methyl-THF

5-Methyltetrahydrofolic acid-[13C5] 5MTHF

Sodium 2-(4-(((2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioate

5-METHYLTETRAHYDROFOLIC ACID DISODIU

5-METHYLTETRAHYDROFOLIC ACID DISODIUM SALT USP/EP/BP

68792-52-9

C20H23N7Na2O6

C20H23N7O62Na

Fluorogenic

Cofactors

Enzymes, Inhibitors, and Substrates

Oxidation-Reduction

Biochemicals and Reagents

BioChemical

Activity