ChemicalBook > CAS DataBase List > 4-Aminohippuric acid

4-Aminohippuric acid

Product Name
4-Aminohippuric acid
CAS No.
61-78-9
Chemical Name
4-Aminohippuric acid
Synonyms
PAH;P-AMINOHIPPURIC ACID;POLYNUCLEAR AROMATIC HYDROCARBONS;paha;Nefrotest;N-glycine;Aminohippuric;pah(aminoacid);AKOS BBS-00006940;p-amino-hippuricaci
CBNumber
CB5348161
Molecular Formula
C9H10N2O3
Formula Weight
194.19
MOL File
61-78-9.mol
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4-Aminohippuric acid Property

Melting point:
199-200 °C (dec.)(lit.)
Boiling point:
330.62°C (rough estimate)
Density 
1.356
refractive index 
1.5600 (estimate)
storage temp. 
Store below +30°C.
solubility 
DMF: 33 mg/ml; DMF:PBS (pH7.2) (1:30): 0.03 mg/ml; DMSO: 20 mg/ml
form 
Crystalline Powder
pka
pKa 3.8 (Uncertain)
color 
Off-white to grayish
PH
3.0-3.5 (20g/l, H2O, 20℃)
Water Solubility 
Soluble in alcohol, chloroform, benzene, and acetone. Insoluble in water, ether, carbon, and tetrachloride.
Merck 
14,442
BRN 
1213676
InChIKey
HSMNQINEKMPTIC-UHFFFAOYSA-N
CAS DataBase Reference
61-78-9(CAS DataBase Reference)
EPA Substance Registry System
P-Aminohippuric acid (61-78-9)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
37/39-26-36
WGK Germany 
3
8-9-23
TSCA 
Yes
HS Code 
29242990
Hazardous Substances Data
61-78-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3174
Product name
Aminohippuric Acid
Purity
pharmaceutical secondary standard, certified reference material
Packaging
500MG
Price
$200
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14621
Product name
4-Aminohippuric acid
Purity
for synthesis
Packaging
25g
Price
$191
Updated
2024/03/01
Sigma-Aldrich
Product number
08090
Product name
p-Aminohippuric acid
Purity
≥98.0% (T)
Packaging
50g
Price
$387
Updated
2023/01/07
TCI Chemical
Product number
A0313
Product name
4-Aminohippuric Acid
Purity
>99.0%(T)
Packaging
10g
Price
$171
Updated
2024/03/01
TCI Chemical
Product number
A0313
Product name
4-Aminohippuric Acid
Purity
>99.0%(T)
Packaging
25g
Price
$342
Updated
2024/03/01
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4-Aminohippuric acid Chemical Properties,Usage,Production

Description

4-Aminohippuric acid is a substrate for various renal transporters that has been used in the study of anion uptake in the kidney. It is a substrate for organic anion transporter 1 (OAT1; Km = 14.3 μM in X. laevis oocytes), the human inorganic phosphate transporter (NPT1; Km = 2.66 mM in HEK293 cells), and apical multidrug resistance protein (MDR2; Km = 880 μM in HEK293 cells). 4-Aminohippuric acid is a glycine amide form of 4-aminobenzoic acid . Formulations containing 4-aminohippuric acid have been used as markers to determine renal plasma flow.

Chemical Properties

off-white to greyish crystalline powder

Uses

muscle relaxant (smooth)

Uses

p-Aminohippuric acid has been used as infusions to measure plasma flow.

Uses

4-Aminohippuric Acid is used in the measurement of renal plasma flow as a diagnostic tool which may be applied towards kidney disorders.

Definition

ChEBI: An N-acylglycine that is the 4-amino derivative of hippuric acid; used as a diagnostic agent in the measurement of renal plasma flow.

General Description

Renal tubules secretes para amino hippuric acid/PAH.

Biochem/physiol Actions

Para-aminohippuric acid?(PAH) is used as a marker in nutrition studies to measure the flow of blood in pigs, which inturn helps to determine the portal-drained viscera (PDV) flux of nutrients.

Purification Methods

Crystallise the acid from H2O. It is soluble in organic solvents. [Cohen & McGilvery J Biol Chem 169 119 1945, 171 121 1947, Meunzen et al. J Biol Chem 26 469 1926, Beilstein 14 III 1069, 14 IV 1152.]

4-Aminohippuric acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Aminohippuric acid Suppliers

Shanghai ChangQi Biochemical Technology Co., Ltd.
Tel
13671867139
Fax
021-68940559
Email
xj8806@163.com
Country
China
ProdList
11
Advantage
55
Changzhou Qiyu Biotechnology Co., Ltd.
Tel
13961298435
Email
zzyqqq@163.com
Country
China
ProdList
47
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
029-81148696 18161915376
Email
1040@dideu.com
Country
China
ProdList
10009
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
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View Lastest Price from 4-Aminohippuric acid manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
4-AMINOHIPPURIC ACID 61-78-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-09-05
Henan Aochuang Chemical Co.,Ltd.
Product
4-AMINOHIPPURIC ACID 61-78-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-14
Career Henan Chemical Co
Product
4-AMINOHIPPURIC ACID 61-78-9
Price
US $0.10/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
1kg; 100kg; 1000kg
Release date
2019-12-24

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