4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline

Product Name: 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
CAS No.: 694499-26-8
Chemical Name: 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
Synonyms: PON50;SW-53;SWF-53;Ponatinib int2;Ponatinib Impurity 3;Pralsetinib Impurity 1;Intermediate of Ponatinib;4-(4-Methylpiperazinomethyl)-3-;4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline;4-(4-Methylpiperazinomethyl)-4-(trifluoromethyl)aniline
CBNumber: CB92520701
Molecular Formula: C13H18F3N3
Formula Weight: 273.3
MOL File: 694499-26-8.mol

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4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline Property

Boiling point:: 329.1±42.0 °C(Predicted)
Density: 1.227
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 7.55±0.10(Predicted)
InChI: InChI=1S/C13H18F3N3/c1-18-4-6-19(7-5-18)9-10-2-3-11(17)8-12(10)13(14,15)16/h2-3,8H,4-7,9,17H2,1H3
InChIKey: ZMWAZMYBMAAMAW-UHFFFAOYSA-N
SMILES: C1(N)=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: M329373
Product name: 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
Packaging: 5g
Price: $250
Updated: 2021/12/16

Matrix Scientific

Product number: 132323
Product name: 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
Purity: 97%
Packaging: 25g
Price: $2700
Updated: 2021/12/16

Apolloscientific

Product number: PC51192
Product name: 4-[(4-Methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline
Purity: 95+%
Packaging: 1g
Price: $17
Updated: 2021/12/16

Oakwood

Product number: 212607
Product name: 4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline
Purity: 95%
Packaging: 1g
Price: $19
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-3-3G
Product name: 4-[(4-Methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline
Purity: 95.0%
Packaging: 1g
Price: $28
Updated: 2021/12/16

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4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline Chemical Properties,Usage,Production

Uses

4-(6-Acryloyloxyhexyloxy)-benzoesure (4-cyanophenylester) can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and in the process of chemical and pharmaceutical synthesis.

Synthesis

4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline Into a solution 4-methyl-1-(4-nitro-2-(trifluoromethyl)benzyl)piperazine (1.5 g, 5 mmol) in MeOH (250 mL) was added Raney Nickel (0.15 g, 10 wt %). The suspension was stirred under hydrogen atmosphere (50 psi) for 24 hrs and monitored by TLC. The reaction mixture was filtered through celite and the filtrate was concentrated under reduced pressure to yield the desired product (1.36 g, 100%). 1H NMR (300 MHz, CDCl3) |?: 7.43-7.46 (1H, d, J=9.0 Hz), 6.91 (1H, s), 6.77-6.80 (1H, d J=9.0 Hz), 3.77 (2H, s), 3.54 (2H, s), 2.53 (8H, brs), 2.34 (3H, s).

storage

Store long-term at 2-8°C.

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline Suppliers

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View Lastest Price from 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline manufacturers

Dorne Chemical Technology co. LTD

Product: 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline 694499-26-8
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg
Release date: 2024-06-25

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline 694499-26-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-22

PNP Biotech Co. Ltd

Product: 4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline 694499-26-8
Price: US $0.00/KG
Min. Order: 25KG
Purity: 98%
Supply Ability: Inquiry
Release date: 2022-09-19

694499-26-8, 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)anilineRelated Search:

1-Methyl-4-[[4-nitro-2-(trifluoromethyl)phenyl]methyl]-piperazine 1-(bromomethyl)-4-nitro-2-(trifluoromethyl)benzene 5-BROMO-2-METHYL-3-NITROPHENYL METHYLCARBOXYLATE 2,4-dichloro-7H-Pyrrolo[2,3-d]pyriMidine-7-carboxylic acid 1,1-diMethylethyl ester 1-METHYL-5-NITRO-1H-INDAZOLE 5-METHYL-4,5,6,7-TETRAHYDRO[1,3]THIAZOLO[5,4-C]PYRIDIN-2-AMINE rac-4-(6-chloro-2-oxo-2,3-dihydro-1H-indol-3-yl)-piperidine-1-carboxylic acid tert-butyl No Chinese name (6-Methylpyridazin-3-yl)MethanaMine dihydrochloride tert-butyl 4-(4-broMothiazol-2-yl)piperazine-1-carboxylate 2-Methylpiperazine 1,2-Dimethylhydrazine Dihydrochloride 1-Methylpiperazine MK-1775 Niraparib Ponatinib Hydrochloride Galeterone Ponatinib

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline

4-((4-Methylpiperazin-1-yl)methyl)-3-trifluoromethylphenylamine

4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline

4-[(4-Methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzenamine

BenzenaMine, 4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)-

4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)aniline

4-[(4-Methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline 95+%

5-Amino-2-[(4-methylpiperazin-1-yl)methyl]benzotrifluoride, 1-[4-Amino-2-(trifluoromethyl)benzyl]-4-methylpiperazine

4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline 4-((4-Methylpiperazin-1-yl)methyl)-3-trifluoromethylphenylamine

Ponatinib Impurity 3

Ponatinib int2

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline IN Stock

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline IN Stock COA TDS free sample

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline TDS msds coa

PON50

4-(4-METHYLPIPERAZINOMETHYL)-3-(TRIFLUOROMETHYL)ANILINE 694499-26-8

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline USP/EP/BP

SWF-53

SW-53

Benzenamine, 4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoro...

3-(trifluoromethyl)-4-((4-methylpiperazin-1-yl)methyl)benzenamine

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline-d8

4-(4-Methylpiperazinomethyl)-4-(trifluoromethyl)aniline

1-[4-Amino-2-(Trifluoromethyl)benzyl]-4-MethylPiperazine

4-(4-Methylpiperazinomethyl)-3-

Pralsetinib Impurity 1

Intermediate of Ponatinib

694499-26-8