Broussonin E
- Product Name
- Broussonin E
- CAS No.
- 90902-21-9
- Chemical Name
- Broussonin E
- Synonyms
- Broussonin E;2-[3-(3-Hydroxy-4-methoxyphenyl)propyl]-5-methoxyphenol;Phenol,2-[3-(3-hydroxy-4-methoxyphenyl)- propyl]-5-methoxy-
- CBNumber
- CB92566604
- Molecular Formula
- C17H20O4
- Formula Weight
- 288.34
- MOL File
- 90902-21-9.mol
Broussonin E Property
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- AS021289
- Product name
- BroussoninE
- Packaging
- 5mg
- Price
- $339
- Updated
- 2021/12/16
- Product number
- CFN97474
- Product name
- BroussoninE
- Packaging
- 5mg
- Price
- $553
- Updated
- 2021/12/16
- Product number
- CD32000143
- Product name
- BroussoninE
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $860
- Updated
- 2021/12/16
Broussonin E Chemical Properties,Usage,Production
Description
Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway, and can be further developed as a promising drug for the treatment of inflammation-related diseases such as atherosclerosis.
Uses
Broussonin E is a phenolic compound and shows anti-inflammatory activity. Broussonin E can suppress inflammation by modulating macrophages activation statevia inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway. Broussonin E can be used for the research of inflammation-related diseases such as atherosclerosis[1].
target
TNF-α | p38 MAPK | ERK | JAK | STAT
IC 50
ERK; p38 MAPK; JAK2; STAT3; IL-1β; IL-6; COX-2; IL-10
References
[1] Huang SP, et al. Broussonin E suppresses LPS-induced inflammatory response in macrophages via inhibiting MAPK pathway and enhancing JAK2-STAT3 pathway. Chin J Nat Med. 2019 May 20;17(5):372-380. DOI:10.1016/S1875-5364(19)30043-3
Broussonin E Preparation Products And Raw materials
Raw materials
Preparation Products
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