CAY10415

Product Name: CAY10415
CAS No.: 146062-49-9
Chemical Name: CAY10415
Synonyms: 0160;CS-1615;CAY10415;MSDC-0160;MSDC-Mitoglitazone;MSDC-0160(CAY10415);CAY10415 MSDC-0160;CAY10415 Exclusive;CAY10415 (Mitoglitazone)
CBNumber: CB92590409
Molecular Formula: C19H18N2O4S
Formula Weight: 370.42
MOL File: 146062-49-9.mol

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CAY10415 Property

Boiling point:: 623.8±55.0 °C(Predicted)
Density: 1.315±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: ≥37 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form: A crystalline solid
pka: 6.32±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1884
Product name: Mitoglitazone
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $102
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML1884
Product name: Mitoglitazone
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $330
Updated: 2023/06/20

Cayman Chemical

Product number: 71748
Product name: CAY10415
Purity: ≥98%
Packaging: 1mg
Price: $39
Updated: 2024/03/01

Cayman Chemical

Product number: 71748
Product name: CAY10415
Purity: ≥98%
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 71748
Product name: CAY10415
Purity: ≥98%
Packaging: 10mg
Price: $189
Updated: 2024/03/01

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CAY10415 Chemical Properties,Usage,Production

Uses

CAY10415 is used to study blood glucose levels and rates of insulin-stimulated lipogenesis.

Definition

ChEBI: 5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]thiazolidine-2,4-dione is an aromatic ether.

Biological Activity

msdc-0160 is a prototype mtot-modulating insulin sensitizer [1].msdc-0160 is a thiazolidinedione insulin sensitizer without the peroxisome proliferator–activated receptor-γ (ppar-γ)-dependent side effects. co-incubation of islets with msdc-0160 and igf-1 reduces the resistance of insulin-signaling pathway and preserves insulin content. msdc-0160 at 50μm alone also prevents the loss of insulin content significantly. besides that, treatment of msdc-0160 increases the phosphorylation of ampk and reduces mtor phosphorylation. moreover, msdc-0160 is also found to display pro-survival effects in human islets via reducing the level of cleaved caspase-3 and increasing the expression of apoptosis-related genes such as bcl2. in addition, msdc-0160 exerts prevention of nuclear translocation with β-catenin localized on the cell membrane or cytoplasm in human β-cells [1].

References

[1] rohatgi n, aly h, marshall c a, et al. novel insulin sensitizer modulates nutrient sensing pathways and maintains β-cell phenotype in human islets. plos one, 2013, 8(5): e62012.

CAY10415 Preparation Products And Raw materials

Raw materials

Preparation Products

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CAY10415 Suppliers

China 60 India 1 United Kingdom 2 United States 12 Global 75

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: meilunui@163.com
Country: China
ProdList: 4727
Advantage: 58

Shanghai Hope Chem Co., Ltd.，

Tel: +21-18501659228 18501659228
Fax: sales@hope-chem.com
Email: info@hope-chem.com
Country: China
ProdList: 483
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4456
Advantage: 55

YouCoChem (Beijing) Chemical Technology Co., Ltd.

Tel: 18800159827
Email: youcochem@163.com
Country: China
ProdList: 161
Advantage: 50

Guangzhou Zhiya Chemdrugs Co.,Ltd

Tel: 18122150900
Fax: QQ:2869377561
Email: sculk28@163.com
Country: China
ProdList: 646
Advantage: 55

Twochem Co.Ltd

Tel: 021-021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 304
Advantage: 55

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
ProdList: 2317
Advantage: 55

146062-49-9, CAY10415Related Search:

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CAY10415

MSDC-0160

CAY10415;CAY-10415;CAY 10415;MSDC 0160;MSDC0160

CS-1615

MITOGLITAZONE;CAY10415;MSDC 0160

2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-

CAY10415 (Mitoglitazone)

Mitoglitazone

5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-Thiazolidinedione

5-(4-(2-(5-Ethylpyridin-2-yl)-2-oxoethoxy)-benzyl)thiazolidine-2,4-dione

MSDC-0160(CAY10415)

CAY10415 MSDC-0160

5-[[4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

MSDC-0160 (Mitoglitazone

CAY10415 Exclusive

0160

MSDC-&#8203

Mitoglitazone (MSDC-0160)

146062-49-9

Inhibitors