CAY10415

Product Name: CAY10415
CAS No.: 146062-49-9
Chemical Name: CAY10415
Synonyms: 0160;CS-1615;CAY10415;MSDC-0160;MSDC-Mitoglitazone;MSDC-0160(CAY10415);CAY10415 MSDC-0160;CAY10415 Exclusive;CAY10415 (Mitoglitazone)
CBNumber: CB92590409
Molecular Formula: C19H18N2O4S
Formula Weight: 370.42
MOL File: 146062-49-9.mol

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CAY10415 Property

Boiling point:: 623.8±55.0 °C(Predicted)
Density: 1.315±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: ≥37 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form: A crystalline solid
pka: 6.32±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1884
Product name: Mitoglitazone
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $102
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML1884
Product name: Mitoglitazone
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $330
Updated: 2023/06/20

Cayman Chemical

Product number: 71748
Product name: CAY10415
Purity: ≥98%
Packaging: 1mg
Price: $39
Updated: 2024/03/01

Cayman Chemical

Product number: 71748
Product name: CAY10415
Purity: ≥98%
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 71748
Product name: CAY10415
Purity: ≥98%
Packaging: 10mg
Price: $189
Updated: 2024/03/01

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CAY10415 Chemical Properties,Usage,Production

Uses

CAY10415 is used to study blood glucose levels and rates of insulin-stimulated lipogenesis.

Definition

ChEBI: 5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]thiazolidine-2,4-dione is an aromatic ether.

Biological Activity

msdc-0160 is a prototype mtot-modulating insulin sensitizer [1].msdc-0160 is a thiazolidinedione insulin sensitizer without the peroxisome proliferator–activated receptor-γ (ppar-γ)-dependent side effects. co-incubation of islets with msdc-0160 and igf-1 reduces the resistance of insulin-signaling pathway and preserves insulin content. msdc-0160 at 50μm alone also prevents the loss of insulin content significantly. besides that, treatment of msdc-0160 increases the phosphorylation of ampk and reduces mtor phosphorylation. moreover, msdc-0160 is also found to display pro-survival effects in human islets via reducing the level of cleaved caspase-3 and increasing the expression of apoptosis-related genes such as bcl2. in addition, msdc-0160 exerts prevention of nuclear translocation with β-catenin localized on the cell membrane or cytoplasm in human β-cells [1].

References

[1] rohatgi n, aly h, marshall c a, et al. novel insulin sensitizer modulates nutrient sensing pathways and maintains β-cell phenotype in human islets. plos one, 2013, 8(5): e62012.

CAY10415 Preparation Products And Raw materials

Raw materials

Preparation Products

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CAY10415 Suppliers

China 61 India 1 United Kingdom 2 United States 13 Global 77

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
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TargetMol Chemicals Inc.

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InvivoChem

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Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
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Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

BOC Sciences

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Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
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BOC Sciences

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Abcam

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Cayman Chemical Company

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United States Biological

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MedChemExpress

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Matrix Scientific

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146062-49-9, CAY10415Related Search:

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CAY10415

MSDC-0160

CAY10415;CAY-10415;CAY 10415;MSDC 0160;MSDC0160

CS-1615

MITOGLITAZONE;CAY10415;MSDC 0160

2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-

CAY10415 (Mitoglitazone)

Mitoglitazone

5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-Thiazolidinedione

5-(4-(2-(5-Ethylpyridin-2-yl)-2-oxoethoxy)-benzyl)thiazolidine-2,4-dione

MSDC-0160(CAY10415)

CAY10415 MSDC-0160

5-[[4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

MSDC-0160 (Mitoglitazone

CAY10415 Exclusive

0160

MSDC-&#8203

Mitoglitazone (MSDC-0160)

Mitoglitazone (MSDC-0160), mTOT modulator

146062-49-9

Inhibitors