ChemicalBook > CAS DataBase List > GS9620

GS9620

Product Name
GS9620
CAS No.
1228585-88-3
Chemical Name
GS9620
Synonyms
Gs-20;CS-925;GS9620;GS-9620;GS 9620;Vesatolimod;GS9620, >=98%;GS 9620; GS9620;GS-9620(Vesatolimod);Vesatolimod GS-9620
CBNumber
CB92666623
Molecular Formula
C22H30N6O2
Formula Weight
410.51
MOL File
1228585-88-3.mol
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GS9620 Property

Density 
1.247±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO (10 mg/ml)
form 
solid
pka
10.34±0.20(Predicted)
color 
Off-white
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19628
Product name
GS-9620
Purity
≥98%
Packaging
5mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
19628
Product name
GS-9620
Purity
≥98%
Packaging
10mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
19628
Product name
GS-9620
Purity
≥98%
Packaging
25mg
Price
$180
Updated
2024/03/01
Cayman Chemical
Product number
19628
Product name
GS-9620
Purity
≥98%
Packaging
100mg
Price
$477
Updated
2024/03/01
ApexBio Technology
Product number
A3444
Product name
GS-9620
Packaging
50mg
Price
$700
Updated
2021/12/16
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GS9620 Chemical Properties,Usage,Production

Description

GS-9620 is a potent and selective oral Toll-like receptor 7 (TLR7) agonist that directly activates plasmacytoid dendritic cells (pDCs). GS-9620 suppressed hepatitis B virus (HBV) in animal models of chronic infection and transiently activated HIV expressionex vivoin latently-infected peripheral blood mononuclear cells (PBMCs) from virally suppressed patients. Currently, GS-9620 is under clinical evaluation for treating chronic HBV infection and for reducing latent reservoirs in virally-suppressed HIV-infected patients.

target

TLR-7

References

Lopatin, U, et al. "Safety, pharmacokinetics and pharmacodynamics of GS-9620, an oral Toll-like receptor 7 agonist." Antiviral Therapy18.3(2013):409-18.
Gane, E. J., et al. "The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection." Journal of Hepatology63.2(2015):320.
Lanford, Robert E., et al. "GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees." Gastroenterology 144.7(2013):1508.

GS9620 Preparation Products And Raw materials

Raw materials

Preparation Products

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GS9620 Suppliers

China 105 India 1 United Kingdom 1 United States 15 Global 122
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from GS9620 manufacturers

Anhui Ruihan Technology Co., Ltd
Product
GS9620 1228585-88-3
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-09-07
Career Henan Chemical Co
Product
GS9620 1228585-88-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2019-08-07

1228585-88-3, GS9620Related Search:

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  • CS-925
  • GS 9620; GS9620
  • Vesatolimod
  • GS9620, >=98%
  • 4-amino-2-butoxy-8-[[3-(pyrrolidin-1-ylmethyl)phenyl]methyl]-5,7-dihydropteridin-6-one
  • 4-amino-2-butoxy-8-(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one
  • 4-Amino-2-butoxy-8-[3-(1-pyrrolidinylmethyl)benzyl]-7,8-dihydro-6(5H)-pteridinone
  • GS 9620
  • GS9620
  • GS-9620
  • 4-Amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-6(5H)-pteridinone
  • 8-(3-(pyrrolidin-1-ylMethyl)benzyl)-4-aMino-2-butoxy-7,8-dihydropteridin-6(5H)-one
  • MFCD25372045 (GS-9620)
  • 4-Amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-6(5H)-pteridinone GS 9620
  • 6(5H)-Pteridinone, 4-amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl] HCl
  • Vesatolimod GS-9620
  • 6(5H)-Pteridinone, 4-amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-
  • Gs-20
  • GS-9620(Vesatolimod)
  • 4-amino-2-butoxy-8-Chemicalbook(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one
  • GS-9620 Vesatolimod GS9620
  • 1228585-88-3
  • 12285885-88-3
  • API