CCR1 antagonist

Product Name: CCR1 antagonist
CAS No.: 1003566-93-5
Chemical Name: CCR1 antagonist
Synonyms: AZD 4818;CCR1 antagonist;AZD-4818, 10 mM in DMSO;HVTUHSABWJPWNK-SFHVURJKSA-N;chemokine,COPD,AZD-4818,AZD4818,CCR1,inhibit,Inhibitor,CCR,AZD 4818,chronic obstructive pulmonary disease,CC chemokine receptor;2-{2-chloro-5-[(2S)-3-{5-chloro-3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl}-2-hydroxypropoxy]-4-(methylcarbamoyl)phenoxy}-2-methylpropanoic acid;Propanoic acid, 2-[2-chloro-5-[(2S)-3-(5-chlorospiro[benzofuran-2(3H),4'-piperidin]-1'-yl)-2-hydroxypropoxy]-4-[(methylamino)carbonyl]phenoxy]-2-methyl-
CBNumber: CB92668324
Molecular Formula: C27H32Cl2N2O7
Formula Weight: 567.46
MOL File: 1003566-93-5.mol

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CCR1 antagonist Property

storage temp.: Store at -20°C
solubility: DMSO : 50 mg/mL (88.11 mM; ultrasonic and adjust pH to 2 with HCl)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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CCR1 antagonist Chemical Properties,Usage,Production

Uses

AZD-4818 is a potent antagonist of chemokine CCR1. AZD-4818 can be used for researching chronic obstructive pulmonary disease (COPD) [1].

References

[1] Norman P. AZD-4818, a chemokine CCR1 antagonist: WO2008103126 and WO2009011653. Expert Opin Ther Pat. 2009;19(11):1629-1633. DOI:10.1517/13543770903118996

CCR1 antagonist Preparation Products And Raw materials

Raw materials

Preparation Products

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CCR1 antagonist Suppliers

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1003566-93-5, CCR1 antagonistRelated Search:

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2-{2-chloro-5-[(2S)-3-{5-chloro-3H-spiro[1-benzofuran-2,4'-piperidin]-1'-yl}-2-hydroxypropoxy]-4-(methylcarbamoyl)phenoxy}-2-methylpropanoic acid

AZD 4818

CCR1 antagonist

HVTUHSABWJPWNK-SFHVURJKSA-N

Propanoic acid, 2-[2-chloro-5-[(2S)-3-(5-chlorospiro[benzofuran-2(3H),4'-piperidin]-1'-yl)-2-hydroxypropoxy]-4-[(methylamino)carbonyl]phenoxy]-2-methyl-

chemokine,COPD,AZD-4818,AZD4818,CCR1,inhibit,Inhibitor,CCR,AZD 4818,chronic obstructive pulmonary disease,CC chemokine receptor

AZD-4818, 10 mM in DMSO

1003566-93-5

C27H32Cl2N2O7