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LEE011 (succinate)

Product Name
LEE011 (succinate)
CAS No.
1374639-75-4
Chemical Name
LEE011 (succinate)
Synonyms
Ribociclib succinate;RIBOCICLIB SUCCINATE (LEE011);LEE011 (succinate);Ribociclib succite;1374639-75-4 LEE011 (succinate);Ribociclib Succinate (Kisqali);RIBOCICLIB SUCCINATE (LEE011 SUCCINATE);LEE-011 succinate salt, Ribociclib succinate salt;7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate
CBNumber
CB92682010
Molecular Formula
C27H36N8O5
Formula Weight
552.64
MOL File
1374639-75-4.mol
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LEE011 (succinate) Property

Melting point:
>160oC (dec.)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H372Causes damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
L321000
Product name
LEE011Succinate
Packaging
50mg
Price
$100
Updated
2021/12/16
TRC
Product number
L321000
Product name
LEE011Succinate
Packaging
10mg
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-2277
Product name
Ribociclibsuccinate
Purity
99.52%
Packaging
10mg
Price
$84
Updated
2021/12/16
ChemScene
Product number
CS-2277
Product name
Ribociclibsuccinate
Purity
99.52%
Packaging
5mg
Price
$60
Updated
2021/12/16
ApexBio Technology
Product number
B1084
Product name
LEE011succinate
Packaging
5mg
Price
$67
Updated
2021/12/16
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LEE011 (succinate) Chemical Properties,Usage,Production

Uses

LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 (a V600E BRAF specific inhibitor) or BYL719 (a PIK3CA specific inhibitor) leads to robust anti-tumor activity in melanoma and breast cancer tumor models.

LEE011 (succinate) Preparation Products And Raw materials

Raw materials

Preparation Products

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LEE011 (succinate) Suppliers

China 114 India 7 Israel 1 United States 10 Global 132
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View Lastest Price from LEE011 (succinate) manufacturers

Hebei Senko Biotechnology Co., Ltd.
Product
LEE011 (succinate) 1374639-75-4
Price
US $10.00/Kg/Bag
Min. Order
1KG
Purity
99%
Supply Ability
10 Tons
Release date
2021-08-02
Career Henan Chemical Co
Product
LEE011 (succinate) 1374639-75-4
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
100kg
Release date
2018-12-19

1374639-75-4, LEE011 (succinate)Related Search:

tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate LEE011 (hydrochloride) Ribociclib Neratinib Maleate 1-Piperazinecarboxylic acid, 4-[6-[[7-cyclopentyl-6-[(diMethylaMino)carbonyl]-7H-pyrrolo[2,3-d]pyriMidin-2-yl]aMino]-3-pyridinyl]-, 1,1-diMethylethyl ester 2-Chloro-7-cyclopentyl-N,N-dimethyl-H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

  • LEE011 (succinate)
  • 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate
  • LEE-011 succinate salt, Ribociclib succinate salt
  • Ribociclib succinate
  • Ribociclib Succinate (Kisqali)
  • RIBOCICLIB SUCCINATE (LEE011 SUCCINATE)
  • Ribociclib succite
  • RIBOCICLIB SUCCINATE (LEE011)
  • 1374639-75-4 LEE011 (succinate)
  • 1374639-75-4
  • C23H30N8OC4H6O4