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tert-butyl 4-ethynyl-4-hydroxypiperidine-1-carboxylate

Product Name
tert-butyl 4-ethynyl-4-hydroxypiperidine-1-carboxylate
CAS No.
275387-83-2
Chemical Name
tert-butyl 4-ethynyl-4-hydroxypiperidine-1-carboxylate
Synonyms
SW-49;SWF-49;EOS-62191;1-Boc-4-ethynylpiperidin-4-ol;1-Boc-4-ethynyl-4-hydroxypiperidine;4-Ethynyl-1-tert-butoxycarbonylpiperidin-4-ol;Tert butyl 4-ethynyl-4-hydroxypiperidine-1-formate;tert-butyl 4-ethynyl-4-hydroxypiperidine-1-carboxylate;4-ethynyl-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester;1-Piperidinecarboxylic acid, 4-ethynyl-4-hydroxy-, 1,1-dimethylethylester
CBNumber
CB92736678
Molecular Formula
C12H19NO3
Formula Weight
225.28
MOL File
275387-83-2.mol
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tert-butyl 4-ethynyl-4-hydroxypiperidine-1-carboxylate Property

Boiling point:
310.9±42.0 °C(Predicted)
Density 
1.11±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
12.84±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B655405
Product name
1-Boc-4-ethynyl-4-hydroxypiperidine
Packaging
100mg
Price
$80
Updated
2021/12/16
Activate Scientific
Product number
AS57652
Product name
1-Boc-4-Ethynyl-4-hydroxypiperidine
Purity
95+%
Packaging
250mg
Price
$113
Updated
2021/12/16
Synthonix
Product number
E14931
Product name
1-Boc-4-ethynyl-4-hydroxypiperidine
Purity
95+%
Packaging
1g
Price
$200
Updated
2021/12/16
Activate Scientific
Product number
AS57652
Product name
1-Boc-4-Ethynyl-4-hydroxypiperidine
Purity
95+%
Packaging
5G
Price
$897
Updated
2021/12/16
Synthonix
Product number
E14931
Product name
1-Boc-4-ethynyl-4-hydroxypiperidine
Purity
95+%
Packaging
10g
Price
$980
Updated
2021/12/16
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tert-butyl 4-ethynyl-4-hydroxypiperidine-1-carboxylate Chemical Properties,Usage,Production

Uses

1-Boc-4-ethynyl-4-hydroxypiperidine is used in preparation of heteroaryl-substituted pyrazolo[1,5-a]pyridines as RET inhibitors, pharmaceutical compounds and uses thereof.

tert-butyl 4-ethynyl-4-hydroxypiperidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl 4-ethynyl-4-hydroxypiperidine-1-carboxylate Suppliers