TMRE
- Product Name
- TMRE
- CAS No.
- 115532-52-0
- Chemical Name
- TMRE
- Synonyms
- TMRE;T 669;TMRE.ClO4;TMRE, PERCHLORATE;TMRE, 10 mM in DMSO;xanthylium perchlorate;3,6-Bis(dimethylamino);TMRE(Tetramethylrhodamine ethyl ester);TETRAMETHYLRHODAMINE ETHYL ESTER PERCHLORATE;TMRE Membrane Potential Fluorescent Probes (Red)
- CBNumber
- CB9279045
- Molecular Formula
- C26H27ClN2O7
- Formula Weight
- 514.96
- MOL File
- 115532-52-0.mol
TMRE Property
- Melting point:
- 264–266℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO: soluble
- form
- crystals
- color
- Dark green
- Appearance
- dark colored solid
- λmax
- 549 nm
- Biological Applications
- Detecting mitochondrial membrane potential; apoptosis assays; multidrug resistance assays
- Major Application
- Semi-conducting polymer nanoparticles
- InChIKey
- NBAOBNBFGNQAEJ-UHFFFAOYSA-M
- SMILES
- Cl([O-])(=O)(=O)=O.C(C1C=CC=CC=1C1C2=CC=C(N(C)C)C=C2[O+]=C2C=C(N(C)C)C=CC=12)(=O)OCC
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/22-36/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- F
- 8-10
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 87917
- Product name
- Tetramethylrhodamine ethyl ester perchlorate
- Purity
- suitable for fluorescence, ≥90% (HPCE)
- Packaging
- 25mg
- Price
- $210
- Updated
- 2025/07/31
- Product number
- 21426
- Product name
- Tetramethylrhodamine ethyl ester (perchlorate)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 21426
- Product name
- Tetramethylrhodamine ethyl ester (perchlorate)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 21426
- Product name
- Tetramethylrhodamine ethyl ester (perchlorate)
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- 21426
- Product name
- Tetramethylrhodamine ethyl ester (perchlorate)
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $195
- Updated
- 2024/03/01
TMRE Chemical Properties,Usage,Production
Description
TMRE is widely used for labeling mitochondria in live cells but not compatible with fixation. This lipophilic and positively charged dye rapidly permeates plasma membrane without interacting with membrane proteins and forming aggregates. TMRE selectively accumulates in active mitochondria due to their transmembrane potential.
In addition to staining mitochondria for imaging purposes, TMRE is used for quantitative measurements of mitochondria membrane potential using Nernst equation. The dye serves as a tool to study mitochondrial function changes and cell viability in response to stimuli or pharmaceuticals of interest. Mitochondrial depolarization caused by apoptosis, necrosis or other factors is characterized by decreased membrane potential and is indicated with decreased fluorescence compared to intact cells that have polarized mitochondria.
TMRE applications include fluorescent microscopy, flow cytometry, microplate assays. The dye has an excitation maximum at 549 nm: it can be effectively excited by the blue (488 nm) or yellow-green (561 nm) lasers. Emission of the dye can be detected in PE channel (maximum at 574 nm).
Uses
Tetramethylrhodamine Ethyl Ester Perchlorate is a fluorescent probe which is used in measuring membrane potential changes in mitochondria.
Definition
ChEBI: Tetramethylrhodamine ethyl ester perchlorate is an organic perchlorate salt that has tetramethylrhodamine ethyl ester(1+) as the cation. It is used as a cell-permeant, cationic, red-orange fluorescent dye that is readily sequestered by active mitochondria. It has a role as a fluorochrome and a reagent. It is a xanthene dye and an organic perchlorate salt. It contains a tetramethylrhodamine ethyl ester(1+).
Abs/Em Maxima
552/575 nm
Excitation / Emission Maximum
550 nm/575 nm
TMRE Preparation Products And Raw materials
Raw materials
Preparation Products
TMRE Suppliers
- Tel
- 029-68881181 13619217766
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- 029-68881181
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- China
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- 010-010-82967028 13522913783
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- +86-10-82967029
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- China
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- 400 638 7771
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- Country
- China
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- 010-62651721 18610486005
- Fax
- 01062651521-808
- minghui.yu@okeanos.com.cn
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- China
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- 495
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- Tel
- 18652989687
- Fax
- +86-25-52131256
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- China
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- Tel
- sales@witofly.com
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- China
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- +86-28-85122536 85324413
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- +86-28-85326443
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- 400-0066400 13621662912
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- 021-55660885
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- China
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- 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
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- China
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- 15873
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- 18622939839
- Fax
- QQ:343281693
- tjby921@163.com
- Country
- China
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- 884
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View Lastest Price from TMRE manufacturers
- Product
- [6-(dimethylamino)-9-(2-ethoxycarbonylphenyl)xanthen-3-ylidene]-dimethylazanium,perchlorate 115532-52-0
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2019-12-31