ChemicalBook > CAS DataBase List > (2-Thiazolyl)methylamine

(2-Thiazolyl)methylamine

Product Name
(2-Thiazolyl)methylamine
CAS No.
55661-33-1
Chemical Name
(2-Thiazolyl)methylamine
Synonyms
2-Thiazolemethamine;2-Thiazolemethanamine;2-AMINOMETHYLTHIAZOLE;thiazol-2-ylMethanaMine;Thiazol-2-yl-methylamine;(2-Thiazolyl)methylamine;2-Aminomethyl-1,3-thiazole;C-THIAZOL-2-YL-METHYLAMINE;(Thiazole-2-ylMethyl)aMine;2-(AMinoMethyl)thiazole 97%
CBNumber
CB9280540
Molecular Formula
C4H6N2S
Formula Weight
114.17
MOL File
55661-33-1.mol
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(2-Thiazolyl)methylamine Property

Melting point:
180-185°C
Boiling point:
36 °C
Density 
1.204 g/mL at 25 °C
refractive index 
n20/D1.569
Flash point:
104℃
storage temp. 
2-8°C(protect from light)
form 
liquid
pka
7.24±0.40(Predicted)
color 
Yellow-green
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Safety

Hazard Codes 
Xi,C
Risk Statements 
22-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2735PSN1 8 / PGII
HazardClass 
IRRITANT, HYGROSCOPIC, CORROSIVE
HS Code 
2934100090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
721522
Product name
2-(Aminomethyl)thiazole
Purity
97%
Packaging
1g
Price
$401
Updated
2025/07/31
TCI Chemical
Product number
T4142
Product name
Thiazol-2-ylmethanamine
Purity
min. 95.0 %
Packaging
200MG
Price
$110
Updated
2025/07/31
TCI Chemical
Product number
T4142
Product name
Thiazol-2-ylmethanamine
Purity
min. 95.0 %
Packaging
1G
Price
$330
Updated
2025/07/31
TRC
Product number
A618280
Product name
2-(Aminomethyl)thiazole
Packaging
250mg
Price
$165
Updated
2021/12/16
Ark Pharm
Product number
P000724298
Product name
Thiazol-2-ylmethanamine
Purity
97%
Packaging
1g
Price
$236
Updated
2021/12/16
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(2-Thiazolyl)methylamine Chemical Properties,Usage,Production

Chemical Properties

Off-white to cream color solid

Uses

(2-Thiazolyl)methylamine is a useful compound in the preparation of cephalosporins

Synthesis

171268-82-9

7732-18-5

55661-33-1

The general procedure for the synthesis of 2-thiazole-methyl-amine from the compound (CAS: 171268-82-9) and water (electrophoretic grade) is as follows: 1. Preparation of GG1 thiazol-2-yl-methylamine azide: triphenylphosphine (2.08 g, 7.9 mmol) was added to a solution of 2-azidomethyl-thiazole (1.11 g, 7.9 mmol) in tetrahydrofuran (THF, 20 mL). 2. Reduction reaction: after 1 h, water (214 μL) and ammonium hydroxide sol (0.5 mL) were added sequentially. 3. Post-treatment: The reaction mixture was stirred overnight and subsequently concentrated under vacuum and purified by fast chromatography (eluent: 5% methanol/dichloromethane) to give the title product 2-thiazolemethanamine as a tan oil (645 mg, 72% yield). 4. The product was characterized by 1H NMR (250 MHz, CDCl3) δ 7.7 (d, 1H, J = 2.0 Hz); 7.25 (d, 1H, J = 2.0 Hz); 4.2 (s, 2H); 1.7 (bs, 2H).

References

[1] Patent: US5939398, 1999, A
[2] Patent: US5698526, 1997, A

(2-Thiazolyl)methylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (2-Thiazolyl)methylamine manufacturers

Career Henan Chemical Co
Product
(2-Thiazolyl)methylamine 55661-33-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-24

55661-33-1, (2-Thiazolyl)methylamineRelated Search:


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  • 55661-33-1
  • C4H6N2SClH
  • C4H8N2SCl2
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