Sulfamerazine sodium
- Product Name
- Sulfamerazine sodium
- CAS No.
- 127-58-2
- Chemical Name
- Sulfamerazine sodium
- Synonyms
- Nsc226823;solumedine;sulfamerazine sodium;SODIUM SULFAMERAZINE;sodiumsulphamerazine;solublesulfamerazine;Pyrimidine sodium sulfa;SULFAMERAZINE SODIUM SALT;SulfadimidineSodium,Pharma;Sulfamerazine sodium USP/EP/BP
- CBNumber
- CB9289260
- Molecular Formula
- C11H13N4NaO2S
- Formula Weight
- 288.3
- MOL File
- 127-58-2.mol
Sulfamerazine sodium Property
- RTECS
- WP0760000
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Powder
- Water Solubility
- Soluble in DMSO or water
- CAS DataBase Reference
- 127-58-2(CAS DataBase Reference)
- EPA Substance Registry System
- Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, monosodium salt (127-58-2)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/22-36/38-36/37/38
- Safety Statements
- 7-24-45-36-26
- WGK Germany
- 3
- TSCA
- Yes
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S0800
- Product name
- Sulfamerazine sodium salt
- Packaging
- 250g
- Price
- $162
- Updated
- 2024/03/01
- Product number
- J66717
- Product name
- Sulfamerazine sodium salt
- Packaging
- 250g
- Price
- $150
- Updated
- 2024/03/01
- Product number
- 23380
- Product name
- Sulfamerazine (sodium salt)
- Purity
- ≥98%
- Packaging
- 10g
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 23380
- Product name
- Sulfamerazine (sodium salt)
- Purity
- ≥98%
- Packaging
- 50g
- Price
- $56
- Updated
- 2024/03/01
- Product number
- 23380
- Product name
- Sulfamerazine (sodium salt)
- Purity
- ≥98%
- Packaging
- 100g
- Price
- $78
- Updated
- 2024/03/01
Sulfamerazine sodium Chemical Properties,Usage,Production
Description
Sulfamerazine is a sulfonamide antibiotic. It inhibits bacterial carbonic anhydrase by ~20% at a concentration of 500 μM. In vivo, sulfamerazine (500 mg/L) reduces severity of peribronchitis and inhibits cilia-associated respiratory Bacillus colonization in mice. It also prevents death of Toxoplasma-infected mice. Sulfonamide class antibiotics, of which sulfamerazine is a member, are bacteriostatic and inhibit bacterial synthesis of dihydrofolic acid by competing with 4-aminobenzoic acid for binding to dihydropteroate synthase. Formulations containing sulfamerazine have been used for the treatment of pneumonia and typhoid fever.
Uses
Involved in characterization of chirosan membranes for the transport of drugs1,2,3
brand name
Bio hubber simple;Cremo-merazine;Debnal m;Mebacid;Neotrizine;Peccocode;Septosil;Spanbolet ii;Tersulpha;Trisulfaminic;Trisulpha.
World Health Organization (WHO)
Sulfamerazine sodium, a sulfonamide anti-infective agent, was introduced several decades ago for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Sulfamerazine is still used in some countries usually in combination with other sulfonamides.
Safety Profile
Moderately toxic by ingestion, subcutaneous, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.
Sulfamerazine sodium Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Sulfamerazine sodium manufacturers
- Product
- Sulfamerazine Sodium 127-58-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2024-04-03
- Product
- Sulfamerazine sodium 127-58-2
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2023-03-29
- Product
- Sulfamerazine sodium 127-58-2
- Price
- US $80.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2021-06-04