ChemicalBook > CAS DataBase List > Amino-PEG4-CH2CO2H

Amino-PEG4-CH2CO2H

Product Name
Amino-PEG4-CH2CO2H
CAS No.
195071-49-9
Chemical Name
Amino-PEG4-CH2CO2H
Synonyms
Amino-PEG4;NH2-PEG4-CH2COOH;H2N-PEG4-CH2COOH;Amino-PEG4-CH2CO4H;Amino-PEG4-CH2COOH;Amino-PEG4-CH2CO2H;AMINE-PEG4-CH2COOH;Amino-PEG4-acetic acid;α-Amino-ω-carboxyl poly(ethylene glycol);14-amino-3,6,9,12-tetraoxatetradecanoic acid
CBNumber
CB93062318
Molecular Formula
C10H21NO6
Formula Weight
251.28
MOL File
195071-49-9.mol
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Amino-PEG4-CH2CO2H Property

Boiling point:
397.6±32.0 °C(Predicted)
Density 
1.156±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
DMSO : 100 mg/mL (397.96 mM; Need ultrasonic)
pka
3.39±0.10(Predicted)
form 
solid
color 
White
InChI
InChI=1S/C10H21NO6/c11-1-2-14-3-4-15-5-6-16-7-8-17-9-10(12)13/h1-9,11H2,(H,12,13)
InChIKey
NPRAKTLKDKKZAV-UHFFFAOYSA-N
SMILES
C(O)(=O)COCCOCCOCCOCCN
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Safety

HS Code 
2942000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Apolloscientific
Product number
BIPG1064
Product name
Amino-PEG4-CH2CO2H
Packaging
50mg
Price
$153
Updated
2021/12/16
Activate Scientific
Product number
AS103934
Product name
H2N-PEG4-CH2COOH
Purity
95+%
Packaging
250mg
Price
$249
Updated
2021/12/16
Apolloscientific
Product number
BIPG1064
Product name
Amino-PEG4-CH2CO2H
Packaging
100mg
Price
$254
Updated
2021/12/16
Apolloscientific
Product number
BIPG1064
Product name
Amino-PEG4-CH2CO2H
Packaging
250mg
Price
$414
Updated
2021/12/16
BroadPharm
Product number
BP-22098
Product name
Amino-PEG4-CH2CO2H
Purity
98%
Packaging
1g
Price
$425
Updated
2021/12/16
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Amino-PEG4-CH2CO2H Chemical Properties,Usage,Production

Description

Amino-PEG4-CH2CO2H is a PEG linker containing an amino group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Uses

Amino-PEG4-CH2CO2H is an important biological reagent for the synthesis of PROTAC and antibody-drug couplings (ADCs). It is also used to prepare Masp inhibitory compounds, Mertk degraders and pyruvate kinase inhibitors.

IC 50

PEGs; Non-cleavable Linker

Amino-PEG4-CH2CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Amino-PEG4-CH2CO2H manufacturers

LAURENT
Product
NH2-PEG4-CH2COOH 195071-49-9
Price
US $403.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-18
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Amino-PEG4-CH2COOH 195071-49-9
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-05
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
α-Amino-ω-carboxyl poly(ethylene glycol) 195071-49-9
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%
Supply Ability
100kg
Release date
2021-06-23

195071-49-9, Amino-PEG4-CH2CO2HRelated Search:


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  • Amino-PEG4-CH2CO2H
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  • 14-Amino-3,6,9,12-tetraoxatetradecan-1-oic acid
  • 195071-49-9
  • PROTAC Linker
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