UNC3866

ChemicalBook > CAS DataBase List > UNC3866

Product Name: UNC3866
CAS No.: 1872382-47-2
Chemical Name: UNC3866
Synonyms: CS-2491;UNC3866;UNC 3866;UNC-3866;UNC3866, 10 mM in DMSO;UNC3866,inhibit,Histone Methyltransferase,UNC-3866,Inhibitor,UNC 3866;N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine methyl ester;L-Serine, N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-, methyl ester;(3S,6S,9S,12S,15S)-Methyl 3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate
CBNumber: CB93153225
Molecular Formula: C43H66N6O8
Formula Weight: 795.02
MOL File: 1872382-47-2.mol

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UNC3866 Property

Boiling point:: 1034.5±65.0 °C(Predicted)
Density: 1.129±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Soluble in DMSO
form: A crystalline solid
pka: 13.39±0.46(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 19237
Product name: UNC3866
Purity: ≥95%
Packaging: 1mg
Price: $48
Updated: 2024/03/01

Cayman Chemical

Product number: 19237
Product name: UNC3866
Purity: ≥95%
Packaging: 5mg
Price: $152
Updated: 2024/03/01

Cayman Chemical

Product number: 19237
Product name: UNC3866
Purity: ≥95%
Packaging: 10mg
Price: $278
Updated: 2024/03/01

Cayman Chemical

Product number: 19237
Product name: UNC3866
Purity: ≥95%
Packaging: 25mg
Price: $578
Updated: 2024/03/01

TRC

Product number: D462375
Product name: N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serineMethylEster
Packaging: 5mg
Price: $420
Updated: 2021/12/16

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UNC3866 Chemical Properties,Usage,Production

Description

UNC3866 is an inhibitor of chromobox homolog 7 (CBX7; K_d = 97 nM). It also binds to CBX4 (K_d = 94 nM) but is greater than 6-fold selective over CBX2, 6, and 8 and the chromodomain Y family (CDY) chromodomains CDY1, L1b, and L2 (K_ds = 0.61-6.3 μM). UNC3866 pretreatment (30 μM) of PC3 lysates completely inhibits chemiprecipitation of CBX7. It induces a senescent-like morphology and reduces growth of PC3 cells with an EC₅₀ value of 7.6 μM.

Uses

Polycomb group proteins (CBX4, CBX7) regulate cell fate decisions during embryogenesis. N-?[4-?(1,?1-Dimethylethyl)?benzoyl]?-?L-?phenylalanyl-?L-?alanyl-?L-?leucyl-?N6,?N6-?diethyl-?L-?lysyl-?L-serine Methyl Ester is a selective antagonist of CBX4 and CBX7 chromodomains. It also inhibits prostate cell proliferation.

UNC3866 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from UNC3866 manufacturers

Career Henan Chemical Co

Product: UNC3866 1872382-47-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-13

1872382-47-2, UNC3866Related Search:

UNC0321 UNC3230 UNC2881 UNC2541 UNC 1079 UNC 0224 UNC0379 UNC 669 UNC2250 UNC-1215 UNC-926 Hydochloride UNC569 UNC0646 NUC-7738 UNC2025 UNC0638 UNC-0642 UNC 0631

UNC3866

N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine methyl ester

CS-2491

UNC 3866;UNC-3866

(3S,6S,9S,12S,15S)-Methyl 3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate

L-Serine, N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-, methyl ester

UNC3866,inhibit,Histone Methyltransferase,UNC-3866,Inhibitor,UNC 3866

UNC3866, 10 mM in DMSO

1872382-47-2

C43H66N6O8