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SPIROXAMINE

Product Name
SPIROXAMINE
CAS No.
118134-30-8
Chemical Name
SPIROXAMINE
Synonyms
IMpulse;KWG 4168;SPIROXAMIN;SPIROXAMINE;Spiro aMine;Spiroxamine 0;Spirocyclovir;Prosper Hoggar;SpiroketalaMine;Spiroxamine [iso]
CBNumber
CB9324635
Molecular Formula
C18H35NO2
Formula Weight
297.48
MOL File
118134-30-8.mol
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SPIROXAMINE Property

Melting point:
<25 °C
Boiling point:
bp 120° at 0.067 hPa
Density 
0.96±0.1 g/cm3(Predicted)
refractive index 
nD20 1.4662
Flash point:
147 °C
storage temp. 
0-6°C
solubility 
Chloroform: Slightly Soluble
pka
6.9(at 25℃)
Stability:
Hygroscopic
LogP
4.880 (est)
EPA Substance Registry System
Spiroxamine (118134-30-8)
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Safety

Hazard Codes 
Xn,N
Risk Statements 
20/21/22-38-43-50/53
Safety Statements 
36/37/39-46-60-61
RIDADR 
UN3082 9/PG 3
WGK Germany 
3
Toxicity
LD50 in rats (mg/kg): ~595 orally; >1600 dermally; LC50 in rats (mg/m3): ~2772 by inhalation; LC50 (96 hr) in rainbow trout: 18.5 mg/l (Dutzmann)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
46443
Product name
Spiroxamine
Purity
mixture of diastereomers
Packaging
100mg
Price
$97.5
Updated
2024/03/01
Cayman Chemical
Product number
25823
Product name
Spiroxamine
Purity
≥95%
Packaging
50mg
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
25823
Product name
Spiroxamine
Purity
≥95%
Packaging
100mg
Price
$76
Updated
2024/03/01
TRC
Product number
S683500
Product name
Spiroxamine
Packaging
1g
Price
$80
Updated
2021/12/16
AK Scientific
Product number
2960AA
Product name
N-((8-(tert-Butyl)-1,4-dioxaspiro[4.5]decan-2-yl)methyl)-N-ethylpropan-1-amine
Packaging
50mg
Price
$152
Updated
2021/12/16
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SPIROXAMINE Chemical Properties,Usage,Production

Description

Spiroxamine is a tertiary amine fungicide and an inhibitor of Δ14 reductase/Δ8→Δ7 isomerase. It inhibits the growth of N. parvum, B. dothidea, D. seriata, and L. theobromae isolates from grape vines (EC50s = 0.97-10.28 mg/L). Spiroxamine (0.03-30 μM) reduces network formation in rat cortical cultures. It is also cytotoxic to MDA-kb2 cells (EC20 = 9.29 μM).

Uses

Spiroxamine is a spiroketalamine fungicide for use on cereal crops. Spiroxamine inhibits ergosterol synthesis. Spiroxamine is used as agricultural fungicide.

Definition

ChEBI: The spiroketal resulting from the formal condensation of 4-tert-butylcyclohexanone with 3-[ethyl(propyl)amino]propane-1,2-diol. An inhibitor of ergosterol synthesis, it is a broad spectrum agricultural fungicide used particularly against powde y mildew in the production of cereals, bananas and grapes.

Metabolic pathway

Spiroxamine is metabolized rapidly in plants, soils, water, and animals via similar degradation pathways. The metabolic pathways include hydrolysis and oxidation at several places in the molecule. Side chains are also degraded to various water-soluble conjugates in animals and in plants, and at the end of complete degradation to natural constituents, carbon dioxide is formed in soils as the principal metabolite. The favorable sorption characteristics rule out any possibility of appreciable translocation in soil. In wheat, the total residue is determined in forage, grain, and harvest-ready straw. In the field studies, the residues in the grain are mostly below 0.05 mg kg-1, and only in a few cases up to 0.3 mg kg-1. In the milk of cows ingesting spiroxamine residues with the feed, no residues are found in the least favorable case. In eggs of laying hens, the residue concentrations are below the limit of quantification. There are no residue concentrations detected in the hen fat, meat, and liver.

SPIROXAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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SPIROXAMINE Suppliers

Klong Industrial Co., Ltd
Tel
519-68231162 13961227312
Fax
0519-68231162
Email
info@klongchem.com
Country
China
ProdList
138
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3750
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4515
Advantage
55
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View Lastest Price from SPIROXAMINE manufacturers

Hebei Zhanyao Biotechnology Co. Ltd
Product
SPIROXAMINE 118134-30-8
Price
US $10.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2021-11-12
Longyan Tianhua Biological Technology Co., Ltd
Product
Spiroxamine 118134-30-8
Price
US $4.00/Kg/Bag
Min. Order
10Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2020-10-29

118134-30-8, SPIROXAMINERelated Search:


  • 8-(1,1-DiMethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro[4.5]decane-2-MethanaMine
  • IMpulse
  • KWG 4168
  • Prosper Hoggar
  • SpiroketalaMine
  • Spiro aMine
  • N-((8-(tert-Butyl)-1,4-dioxaspiro[4.5]decan-2-yl)methyl)-N-ethylpropan-1-amine
  • Spiroxamine 0
  • SPIROXAMIN
  • SPIROXAMINE
  • 1,4-Dioxaspiro4.5decane-2-methanamine, 8-(1,1-dimethylethyl)-N-ethyl-N-propyl-
  • n-ethyl-n-propyl-8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-ylmethylamine
  • spiroxamine (iso proposed)
  • Spiroxamine [iso]
  • Spiroxamine 100mg [118134-30-8]
  • SpiroxamineSolution,100mg/L,5x1ml
  • Spiroxamine Standard(mixture of isomers)
  • Spiroxamine@1000 μg/mL in Acetonitrile
  • SpiroxamineSolution,100mg/L,1ml
  • Spiroxamine solution in Methanol,100μg/mL
  • Spirocyclovir
  • 118134-30-8
  • C18H35NO2
  • Agro-Products
  • Amines
  • Heterocycles