SPIROXAMINE

ChemicalBook > CAS DataBase List > SPIROXAMINE

Product Name: SPIROXAMINE
CAS No.: 118134-30-8
Chemical Name: SPIROXAMINE
Synonyms: IMpulse;KWG 4168;SPIROXAMIN;SPIROXAMINE;Spiro aMine;Spirocycline;Spiroxamine 0;Spirocyclovir;Prosper Hoggar;SpiroketalaMine
CBNumber: CB9324635
Molecular Formula: C18H35NO2
Formula Weight: 297.48
MOL File: 118134-30-8.mol

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SPIROXAMINE Property

Melting point:: <25 °C
Boiling point:: bp 120° at 0.067 hPa
Density: 0.96±0.1 g/cm3(Predicted)
refractive index: nD20 1.4662
Flash point:: 147 °C
storage temp.: 0-6°C
solubility: Chloroform: Slightly Soluble
pka: 6.9(at 25℃)
form: Liquid
color: Colorless to light yellow
Stability:: Hygroscopic
LogP: 4.880 (est)
EPA Substance Registry System: Spiroxamine (118134-30-8)

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Safety

Hazard Codes: Xn,N
Risk Statements: 20/21/22-38-43-50/53
Safety Statements: 36/37/39-46-60-61
RIDADR: UN3082 9/PG 3
WGK Germany: 3
Toxicity: LD50 in rats (mg/kg): ~595 orally; >1600 dermally; LC50 in rats (mg/m3): ~2772 by inhalation; LC50 (96 hr) in rainbow trout: 18.5 mg/l (Dutzmann)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 46443
Product name: Spiroxamine
Purity: mixture of diastereomers
Packaging: 100mg
Price: $97.5
Updated: 2024/03/01

Cayman Chemical

Product number: 25823
Product name: Spiroxamine
Purity: ≥95%
Packaging: 50mg
Price: $40
Updated: 2024/03/01

Cayman Chemical

Product number: 25823
Product name: Spiroxamine
Purity: ≥95%
Packaging: 100mg
Price: $76
Updated: 2024/03/01

TRC

Product number: S683500
Product name: Spiroxamine
Packaging: 1g
Price: $80
Updated: 2021/12/16

AK Scientific

Product number: 2960AA
Product name: N-((8-(tert-Butyl)-1,4-dioxaspiro[4.5]decan-2-yl)methyl)-N-ethylpropan-1-amine
Packaging: 50mg
Price: $152
Updated: 2021/12/16

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SPIROXAMINE Chemical Properties,Usage,Production

Description

Spiroxamine is a tertiary amine fungicide and an inhibitor of Δ¹⁴ reductase/Δ⁸→Δ⁷ isomerase. It inhibits the growth of N. parvum, B. dothidea, D. seriata, and L. theobromae isolates from grape vines (EC₅₀s = 0.97-10.28 mg/L). Spiroxamine (0.03-30 μM) reduces network formation in rat cortical cultures. It is also cytotoxic to MDA-kb2 cells (EC₂₀ = 9.29 μM).

Uses

Spiroxamine is a spiroketalamine fungicide for use on cereal crops. Spiroxamine inhibits ergosterol synthesis. Spiroxamine is used as agricultural fungicide.

Definition

ChEBI: The spiroketal resulting from the formal condensation of 4-tert-butylcyclohexanone with 3-[ethyl(propyl)amino]propane-1,2-diol. An inhibitor of ergosterol synthesis, it is a broad spectrum agricultural fungicide used particularly against powde y mildew in the production of cereals, bananas and grapes.

Metabolic pathway

Spiroxamine is metabolized rapidly in plants, soils, water, and animals via similar degradation pathways. The metabolic pathways include hydrolysis and oxidation at several places in the molecule. Side chains are also degraded to various water-soluble conjugates in animals and in plants, and at the end of complete degradation to natural constituents, carbon dioxide is formed in soils as the principal metabolite. The favorable sorption characteristics rule out any possibility of appreciable translocation in soil. In wheat, the total residue is determined in forage, grain, and harvest-ready straw. In the field studies, the residues in the grain are mostly below 0.05 mg kg^-1, and only in a few cases up to 0.3 mg kg^-1. In the milk of cows ingesting spiroxamine residues with the feed, no residues are found in the least favorable case. In eggs of laying hens, the residue concentrations are below the limit of quantification. There are no residue concentrations detected in the hen fat, meat, and liver.

SPIROXAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from SPIROXAMINE manufacturers

Hebei Zhanyao Biotechnology Co. Ltd

Product: SPIROXAMINE 118134-30-8
Price: US $10.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-11-12

Longyan Tianhua Biological Technology Co., Ltd

Product: Spiroxamine 118134-30-8
Price: US $4.00/Kg/Bag
Min. Order: 10Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2020-10-29

118134-30-8, SPIROXAMINERelated Search:

Lenalidomide Chidamide Dimethomorph Tridemorph DODEMORPH FENPROPIMORPH Fenpropidin Flumorph SPIROXAMINE SOLUTION 100UG/ML IN ACETONITRILE 1ML SPIROXAMINE SOLUTION 100UG/ML IN TOLUENE 1ML SPIROXAMINE 1,4-Dioxaspiro[4.5]decane-2-methanamine

8-(1,1-DiMethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro[4.5]decane-2-MethanaMine

IMpulse

KWG 4168

Prosper Hoggar

SpiroketalaMine

Spiro aMine

N-((8-(tert-Butyl)-1,4-dioxaspiro[4.5]decan-2-yl)methyl)-N-ethylpropan-1-amine

Spiroxamine 0

SPIROXAMIN

SPIROXAMINE

1,4-Dioxaspiro4.5decane-2-methanamine, 8-(1,1-dimethylethyl)-N-ethyl-N-propyl-

n-ethyl-n-propyl-8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-ylmethylamine

spiroxamine (iso proposed)

Spiroxamine [iso]

Spiroxamine 100mg [118134-30-8]

SpiroxamineSolution,100mg/L,5x1ml

Spiroxamine Standard(mixture of isomers)

Spiroxamine@1000 μg/mL in Acetonitrile

SpiroxamineSolution,100mg/L,1ml

Spiroxamine solution in Methanol，100μg/mL

Spirocyclovir

Spirocycline

C16973000 Spiroxamine

L16973000ALSpiroxaminE10μg/mLin Acetonitril

Spiroxamine 10.0 μg/ml Acetonitrile

Spiroxamine in Acetonitrile

118134-30-8

C18H35NO2

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