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SPIROXAMINE

Product Name
SPIROXAMINE
CAS No.
118134-30-8
Chemical Name
SPIROXAMINE
Synonyms
IMpulse;KWG 4168;SPIROXAMIN;SPIROXAMINE;Spiro aMine;Spirocycline;Spiroxamine 0;Spirocyclovir;Prosper Hoggar;SpiroketalaMine
CBNumber
CB9324635
Molecular Formula
C18H35NO2
Formula Weight
297.48
MOL File
118134-30-8.mol
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SPIROXAMINE Property

Melting point:
<25 °C
Boiling point:
bp 120° at 0.067 hPa
Density 
0.96±0.1 g/cm3(Predicted)
refractive index 
nD20 1.4662
Flash point:
147 °C
storage temp. 
0-6°C
solubility 
Chloroform: Slightly Soluble
pka
6.9(at 25℃)
form 
Liquid
color 
Colorless to light yellow
Stability:
Hygroscopic
LogP
4.880 (est)
EPA Substance Registry System
Spiroxamine (118134-30-8)
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Safety

Hazard Codes 
Xn,N
Risk Statements 
20/21/22-38-43-50/53
Safety Statements 
36/37/39-46-60-61
RIDADR 
UN3082 9/PG 3
WGK Germany 
3
Toxicity
LD50 in rats (mg/kg): ~595 orally; >1600 dermally; LC50 in rats (mg/m3): ~2772 by inhalation; LC50 (96 hr) in rainbow trout: 18.5 mg/l (Dutzmann)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
46443
Product name
Spiroxamine
Purity
mixture of diastereomers
Packaging
100mg
Price
$97.5
Updated
2024/03/01
Cayman Chemical
Product number
25823
Product name
Spiroxamine
Purity
≥95%
Packaging
50mg
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
25823
Product name
Spiroxamine
Purity
≥95%
Packaging
100mg
Price
$76
Updated
2024/03/01
TRC
Product number
S683500
Product name
Spiroxamine
Packaging
1g
Price
$80
Updated
2021/12/16
AK Scientific
Product number
2960AA
Product name
N-((8-(tert-Butyl)-1,4-dioxaspiro[4.5]decan-2-yl)methyl)-N-ethylpropan-1-amine
Packaging
50mg
Price
$152
Updated
2021/12/16
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SPIROXAMINE Chemical Properties,Usage,Production

Description

Spiroxamine is a tertiary amine fungicide and an inhibitor of Δ14 reductase/Δ8→Δ7 isomerase. It inhibits the growth of N. parvum, B. dothidea, D. seriata, and L. theobromae isolates from grape vines (EC50s = 0.97-10.28 mg/L). Spiroxamine (0.03-30 μM) reduces network formation in rat cortical cultures. It is also cytotoxic to MDA-kb2 cells (EC20 = 9.29 μM).

Uses

Spiroxamine is a spiroketalamine fungicide for use on cereal crops. Spiroxamine inhibits ergosterol synthesis. Spiroxamine is used as agricultural fungicide.

Definition

ChEBI: The spiroketal resulting from the formal condensation of 4-tert-butylcyclohexanone with 3-[ethyl(propyl)amino]propane-1,2-diol. An inhibitor of ergosterol synthesis, it is a broad spectrum agricultural fungicide used particularly against powde y mildew in the production of cereals, bananas and grapes.

Metabolic pathway

Spiroxamine is metabolized rapidly in plants, soils, water, and animals via similar degradation pathways. The metabolic pathways include hydrolysis and oxidation at several places in the molecule. Side chains are also degraded to various water-soluble conjugates in animals and in plants, and at the end of complete degradation to natural constituents, carbon dioxide is formed in soils as the principal metabolite. The favorable sorption characteristics rule out any possibility of appreciable translocation in soil. In wheat, the total residue is determined in forage, grain, and harvest-ready straw. In the field studies, the residues in the grain are mostly below 0.05 mg kg-1, and only in a few cases up to 0.3 mg kg-1. In the milk of cows ingesting spiroxamine residues with the feed, no residues are found in the least favorable case. In eggs of laying hens, the residue concentrations are below the limit of quantification. There are no residue concentrations detected in the hen fat, meat, and liver.

SPIROXAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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SPIROXAMINE Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
Caledon Laboratories Ltd.
Tel
--
Fax
--
Email
tech@caledonlabs.com
Country
Canada
ProdList
1149
Advantage
68
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View Lastest Price from SPIROXAMINE manufacturers

Hebei Zhanyao Biotechnology Co. Ltd
Product
SPIROXAMINE 118134-30-8
Price
US $10.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2021-11-12
Longyan Tianhua Biological Technology Co., Ltd
Product
Spiroxamine 118134-30-8
Price
US $4.00/Kg/Bag
Min. Order
10Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2020-10-29

118134-30-8, SPIROXAMINERelated Search:


  • 8-(1,1-DiMethylethyl)-N-ethyl-N-propyl-1,4-dioxaspiro[4.5]decane-2-MethanaMine
  • IMpulse
  • KWG 4168
  • Prosper Hoggar
  • SpiroketalaMine
  • Spiro aMine
  • N-((8-(tert-Butyl)-1,4-dioxaspiro[4.5]decan-2-yl)methyl)-N-ethylpropan-1-amine
  • Spiroxamine 0
  • SPIROXAMIN
  • SPIROXAMINE
  • 1,4-Dioxaspiro4.5decane-2-methanamine, 8-(1,1-dimethylethyl)-N-ethyl-N-propyl-
  • n-ethyl-n-propyl-8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-ylmethylamine
  • spiroxamine (iso proposed)
  • Spiroxamine [iso]
  • Spiroxamine 100mg [118134-30-8]
  • SpiroxamineSolution,100mg/L,5x1ml
  • Spiroxamine Standard(mixture of isomers)
  • Spiroxamine@1000 μg/mL in Acetonitrile
  • SpiroxamineSolution,100mg/L,1ml
  • Spiroxamine solution in Methanol,100μg/mL
  • Spirocyclovir
  • Spirocycline
  • C16973000 Spiroxamine
  • L16973000ALSpiroxaminE10μg/mLin Acetonitril
  • Spiroxamine 10.0 μg/ml Acetonitrile
  • Spiroxamine in Acetonitrile
  • 118134-30-8
  • C18H35NO2
  • Agro-Products
  • Amines
  • Heterocycles