Anhydrosafflor yellow B
- Product Name
- Anhydrosafflor yellow B
- CAS No.
- 184840-84-4
- Chemical Name
- Anhydrosafflor yellow B
- Synonyms
- AHSYB;Anhydrosafflor yellow B;(2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1;4(2H)-Benzofuranone, 7-β-D-glucopyranosyl-3-[3-β-D-glucopyranosyl-2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-6-oxo-1,4-cyclohexadien-1-yl]-3,7-dihydro-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-, (2S,3S)-
- CBNumber
- CB93313458
- Molecular Formula
- C48H52O26
- Formula Weight
- 1044.92
- MOL File
- 184840-84-4.mol
Anhydrosafflor yellow B Property
- Boiling point:
- 1462.3±65.0 °C(Predicted)
- Density
- 1.88±0.1 g/cm3(Predicted)
- pka
- 4.50±1.00(Predicted)
- form
- Solid
- color
- Light yellow to yellow
N-Bromosuccinimide Price
- Product number
- CS-0032088
- Product name
- AnhydrosaffloryellowB
- Packaging
- 1mg
- Price
- $255
- Updated
- 2021/12/16
Anhydrosafflor yellow B Chemical Properties,Usage,Production
Description
Safflower, also known as red and blue flower, thorn safflower, mainly contains compounds such as chalcone pigments, flavonoids, phenolic acids, steroids and polysaccharides. Among the safflower yellows, hydroxyl safflower yellow A and dehydrated safflower yellow B (AHSYB) have the highest content, which are the main active ingredients with physiological activity in safflower.Anhydrosafflor yellow B can improve heart and brain blood oxygen supply, reduce ischemic injury, anticoagulant, anti-myocardial ischemia, inhibit platelet aggregation, anti-oxidation, anti-tumor and anti-inflammation and other pharmacological effects.
Uses
Anhydrosafflor yellow B (AHSYB) is a quinochalcone C-glycoside isolated from Carthamus tinctorius. Anhydrosafflor yellow B inhibits ADP-induced platelet aggregation, exhibits significant anti-oxidative effects in vitro, and possesses certain activity against H2O2-induced cytotoxicity in cultured PC12 cells and primary neuronal cells[1].
Biological Activity
Anhydrosafflor yellow B (AHSYB) is a quinolone C-glycoside isolated from Carthamus tinctorius. It inhibits ADP-induced platelet aggregation, has significant antioxidant effects in vitro, and has antitoxic activity against H2O2-induced PC12 cells and primary neuronal cells.
Synthesis
A method for extracting and purifying dehydrated safflower yellow B in safflower, 1) using warm soaking method to obtain safflower water extract; 2) pretreatment of macroporous adsorption resin; 3) macroporous resin adsorption; 4) macroporous resin Pore resin elution.
References
[1] Yue S, et al. Metabolic profile of anhydrosafflor yellow B in rats by ultra-fast liquid chromatography/quadrupole time-of-flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2016;1014:37-44. DOI:10.1016/j.jchromb.2016.01.047
Anhydrosafflor yellow B Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Anhydrosafflor yellow B manufacturers
- Product
- Anhydrosafflor yellow B 184840-84-4
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-16