ChemicalBook > CAS DataBase List > 6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER

6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER

Product Name: 6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER
CAS No.: 92557-81-8
Chemical Name: 6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER
Synonyms: 6-FAM-NHS;6-FAM, SE;5/6-FAM-OSu;6-FAM SE (Green);6-FAM SE, 6-CF SE;6-FAM-SEor6-FAM-NHS;6-CARBOXYFLUORESCEIN SE;6-FAM SE, 10 mM in DMSO;6-CARBOXYFLUORESCEIN-NHS;-xanthene]-6-carboxylate
CBNumber: CB9334911
Molecular Formula: C25H15NO9
Formula Weight: 473.39
MOL File: 92557-81-8.mol

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6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER Property

Melting point:: >168°C (dec.)
Boiling point:: 788.1±70.0 °C(Predicted)
Density: 1.74±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: Soluble in N,N-dimethylformamide,dimethyl sulfoxide
pka: 9.31 ± 0.20, most acidic, temperature:25 °C
form: Solid
color: Orange solid
Appearance: Yellow solid
ex/em: 492/517 nm
ε(extinction coefficient): 74,000 L⋅mol−1⋅cm−1
Φ(quantum yield): 0.93
λmax: 496 nm (Buffer pH9)
Stability:: Moisture Sensitive
Biological Applications: Analyzing aminoglycosides; analyzing/determining gabapentin; detecting/analyzing baclofen in human plasma at micromolar level; determining phosphorus-containing amino acid herbicides; multiplex genetic analysis; visualizing/detecting proteins; for synthesizing vancomycin analogs, vasopressin analogs; as a substrate for measuring kinase activity, phosphatase activity.
InChI: InChI=1S/C25H15NO9/c27-13-2-5-16-19(10-13)33-20-11-14(28)3-6-17(20)25(16)18-9-12(1-4-15(18)24(32)34-25)23(31)35-26-21(29)7-8-22(26)30/h1-6,9-11,27-28H,7-8H2
InChIKey: VDABVNMGKGUPEY-UHFFFAOYSA-N
SMILES: C12(C3=C(C=C(O)C=C3)OC3=C1C=CC(O)=C3)C1=C(C=CC(C(ON3C(=O)CCC3=O)=O)=C1)C(=O)O2
CAS DataBase Reference: 92557-81-8(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 8-10-21
HS Code: 29252900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological

Product number: 267964
Product name: 6-Carboxyfluorescein-N-hydroxysuccinimide ester
Packaging: 10mg
Price: $446
Updated: 2021/12/16

TRC

Product number: C178355
Product name: 6-Carboxyfluorescein-N-hydroxysuccinimideEster
Packaging: 100mg
Price: $760
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC19778
Product name: 6-Carboxyfluorescein-N-hydroxysuccinimide ester
Packaging: 10mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC19778
Product name: 6-Carboxyfluorescein-N-hydroxysuccinimide ester
Packaging: 25mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC19778
Product name: 6-Carboxyfluorescein-N-hydroxysuccinimide ester
Packaging: 50mg
Price: $150
Updated: 2021/12/16

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6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER Chemical Properties,Usage,Production

Description

Fluorescein (FAM) is a bright fluorophore that has found an extremely wide application in life science research. The fluorophore is hydrophilic and its derivatives possess good solubility in aqueous buffers.

Fluorescein is compatible with a wide variety of fluorescent instrumentation - most instruments are equipped with FAM channel filters.

This product contains the pure 6-isomer of fluorescein.

Chemical Properties

Yellow to orange powder

Uses

(6-FAM-SE) 6-Carboxyfluorescein-N-hydroxysuccinimide Ester is a commonly used fluorescent reagent for the labelling of peptides, proteins and nucleotides.

Uses

Intracellular pH probe. Fluorescent label for amines and alcohols.

Definition

ChEBI: 6-carboxyfluorescein succinimidyl ester is an N-hydroxysuccinimide ester derived from 6-carboxyfluorescein. A fluorescent cell staining dye, it is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecules, notably to intracellular lysine residues. It has a role as a fluorochrome. It is functionally related to a fluorescein (lactone form).

Abs/Em Maxima

492/517 nm

Fluoresene quantum yield

0.93

Extinction Coefficient

74000

CF260

0.22

CF280

0.17

6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER manufacturers

Career Henan Chemical Co

Product: 6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER 92557-81-8
Price: US $2.00/KG
Min. Order: 1g
Purity: 98%min
Supply Ability: ask
Release date: 2020-01-08

92557-81-8, 6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTERRelated Search:

6-Carboxytetramethylrhodamine 5(6)-Carboxyfluorescein 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester 5-Carboxytetramethylrhodamine 6-Carboxytetramethylrhodamine succinimidyl ester 4',6-Diamidino-2-phenylindole dihydrochloride 6-CARBOXYTETRAMETHYLRHODAMINE N-HYDROXYSUCCINIMIDE ESTER 5-Carboxyfluorescein 5(6)-Carboxytetramethylrhodamine 6-Carboxyfluorescein 5-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER 5(6)-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER,4(5)-carboxyfluorescein N-succinimidyl ester 5(6)-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER 5-(6)-carboxyfluorescein diacetate succinimidyl ester 5-(AND-6)-CARBOXYFLUORESCEIN DIACETATE, SUCCINIMIDYL ESTER

6-CARBOXYFLUORESCEIN SUCCINIMIDE ESTER

6-CARBOXYFLUORESCEIN, SUCCINIMIDYL ESTER

6-CARBOXYFLUORESCEIN-NHS

6-CARBOXYFLUORESCEIN-N-HYDROXYSUCCINIMIDE ESTER

6-CARBOXYFLUORESCEIN N-SUCCINIMIDYL ESTER

6-CARBOXYFLUORESCEIN, SUCCINIMIDYL*ESTER (SINGLE IS

6-CARBOXYFLUORESCEIN,SUCCINIMIDYL ESTER,6-FAM,SE 98%

6-CARBOXYFLUORESCEIN N-HYDROXYSUCCINIMIDE

6-Carboxyfluorescein N-succinimidyl ester, 6-FAM, SE

6-FAM SE, 6-CF SE

1-[[3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl]carbonyl]oxy]-2,5-pyrrolidinedione

Fluorescein-6-carboxylic Acid

CarboxyfluoresceinN-hydroxysucciniMideeste

6-FAM-SEor6-FAM-NHS

6-FAM-NHS

6-FAM, SE

6-CARBOXYFLUORESCEIN SE

6-CarboxyfluoresceinN-succinimidyl ester≥ 90% (HPLC, 254 nm)

6-FAM, SE [6-Carboxyfluorescein, succinimidyl ester] *CAS 92557-81-8*

-xanthene]-6-carboxylate

6-FAM, SE [6-Carboxyfluorescein, succinimidyl ester

6-Carboxyfluorescein N-hydroxysuccinimide ester, 6-FAM-NHS

Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 3',6'-dihydroxy-3-oxo-, 2,5-dioxo-1-pyrrolidinyl ester

2,5-dioxopyrrolidin-1-yl 3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylate

5/6-FAM-OSu

6-FAM SE,6-FAM-NHS,6-Carboxyfluorescein N-hydroxysuccinimide ester

6-FAM-OSu(6-carboxyfluoresceinSE)

6-Carboxyfluorescein N-hydroxysuccinimide ester, Fluorescent labeling reagent

6-FAM SE, 10 mM in DMSO

6-FAM, SE [6-Carboxyfluorescein, SE]

6-Carboxyfluoresceinsuccinimidylether

6-FAM SE (Green)

92557-81-8

C25H15NO9

BioChemical

Biochemicals and Reagents

Detection

Fluorescent Probes, Labels, Particles and Stains

Fluorescent Labels

Fluorescein and Derivatives

marker

Aromatics

Fluorescent Labels & Indicators

Heterocycles

FLUOROPHORES

FAM