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Eprazinone dihydrochloride

Product Name
Eprazinone dihydrochloride
CAS No.
10402-53-6
Chemical Name
Eprazinone dihydrochloride
Synonyms
746CE;Mucitux;Eftapan;Resplen;Rozuplen;NSC 317935;Eprazinone 2HCl;Eprazinone diHCl;EPRAZINONE HYDROCHLORIDE;Eprazinone 2hydrochloride
CBNumber
CB9371811
Molecular Formula
C24H33ClN2O2
Formula Weight
416.99
MOL File
10402-53-6.mol
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Eprazinone dihydrochloride Property

Melting point:
201° (Toffel-Nadolny, Gielsdorf); mp 160° (Mauvernay)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
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Safety

Toxicity
LD50 in mice (mg/kg): 729 orally, 38 i.v. (Vacher)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
448353
Product name
Eprazinone Dihydrochloride
Packaging
50mg
Price
$355
Updated
2021/12/16
TRC
Product number
E590020
Product name
EprazinoneDihydrochloride
Packaging
250mg
Price
$215
Updated
2021/12/16
ChemScene
Product number
CS-0019683
Product name
Eprazinonedihydrochloride
Packaging
250mg
Price
$225
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
94335
Product name
Eprazinone Dihydrochloride
Packaging
50mg
Price
$375
Updated
2021/12/16
ChemScene
Product number
CS-0019683
Product name
Eprazinonedihydrochloride
Packaging
500mg
Price
$380
Updated
2021/12/16
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Eprazinone dihydrochloride Chemical Properties,Usage,Production

Originator

Mucitux,Riom,France,1969

Uses

Eprazinone Dihydrochloride is a drug used to improve pulmonary function in patients with chronic bronchitis.

Definition

ChEBI: A hydrochloride obtained by combining eprazinone with two molar equivalents of hydrochloric acid.

Manufacturing Process

61.4 g of 0.2M of 1-(2-phenyl-2-ethoxy)piperazine dihydrochloride, 33.5 g (0.25M) propiophenone, 75 g (0.25M) trioxymethylene, 120 ml of ethanol and 0.4 ml of concentrated HCl are heated under reflux for 4 to 5 hours. The product is allowed to crystallize, then filtered and washed with alcohol. It is dried and recrystallized from methanol containing 10% H2O.
There is thus obtained 60 g of a white crystalline powder soluble in water. Yield: 66%. Melting point: 160°C.

Therapeutic Function

Antitussive

Eprazinone dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Eprazinone dihydrochloride Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Shanghai Everchem Co., Ltd
Tel
86-29-81325371
Fax
+86-29-81325373
Email
info@everchem.cn
Country
China
ProdList
84
Advantage
62
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Wuhan DKY Technology Co.,Ltd.
Tel
27-81302488 18007166089
Fax
027-81302088
Email
info@dkybpc.com
Country
China
ProdList
2024
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
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58
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60

10402-53-6, Eprazinone dihydrochlorideRelated Search:


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