ChemicalBook > CAS DataBase List > 3,5-Dichloroaniline

3,5-Dichloroaniline

Product Name
3,5-Dichloroaniline
CAS No.
626-43-7
Chemical Name
3,5-Dichloroaniline
Synonyms
3,5-DCA;BF352-31;3,5-dichloro;m-Dichloroaniline;AKOS BBS-00003558;3,5-Dichloranilin;3,5 DICHLORANILINE;TIMTEC-BB SBB008349;3,5-DICHLOROANILINE;3,5-dichloro-anilin
CBNumber
CB9402144
Molecular Formula
C6H5Cl2N
Formula Weight
162.02
MOL File
626-43-7.mol
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3,5-Dichloroaniline Property

Melting point:
46-52 °C (lit.)
Boiling point:
259-260 °C/741 mmHg (lit.)
Density 
1.58
vapor pressure 
40 hPa ( 150 °C)
refractive index 
1.6000 (estimate)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
0.78g/l
pka
pK1:2.37(+1) (25°C)
form 
crystalline
color 
dark gray
Water Solubility 
0.6 g/L (26 ºC)
BRN 
636492
LogP
2.9 at 20-25℃
CAS DataBase Reference
626-43-7(CAS DataBase Reference)
NIST Chemistry Reference
Benzenamine, 3,5-dichloro-(626-43-7)
EPA Substance Registry System
3,5-Dichloroaniline (626-43-7)
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Safety

Hazard Codes 
T,N,Xi
Risk Statements 
23/24/25-33-50/53
Safety Statements 
28-36/37-45-60-61-28A
RIDADR 
UN 3442 6.1/PG 2
WGK Germany 
3
F 
8
Autoignition Temperature
620°C
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29214210
Hazardous Substances Data
626-43-7(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D55792
Product name
3,5-Dichloroaniline
Purity
≥98%
Packaging
10g
Price
$48.2
Updated
2025/07/31
Sigma-Aldrich
Product number
D55792
Product name
3,5-Dichloroaniline
Purity
≥98%
Packaging
100g
Price
$85.2
Updated
2025/07/31
Sigma-Aldrich
Product number
8.41790
Product name
3,5-Dichloroaniline
Purity
for synthesis
Packaging
100G
Price
$133
Updated
2025/07/31
TCI Chemical
Product number
D0325
Product name
3,5-Dichloroaniline
Purity
>98.0%(GC)
Packaging
25g
Price
$60
Updated
2025/07/31
TCI Chemical
Product number
D0325
Product name
3,5-Dichloroaniline
Purity
>98.0%(GC)
Packaging
100g
Price
$179
Updated
2025/07/31
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3,5-Dichloroaniline Chemical Properties,Usage,Production

Chemical Properties

white to brown crystals or needle crystal, soluble in ethanol, ether, diethyl carbonate, insoluble in water, high toxicity, corrosive.

Uses

Dichlorobenzenamine is used in the synthesis of effective inhibitors of plant δ1-pyrroline-4-carboxylate reductase. Also used in the preparation of anti-tumor agents based upon diaryl urea derivatives.

Application

3,5-Dichloroaniline is used in the production of pesticides, dyes and pharmaceuticals. 3,5-Dichloroaniline is an intermediate in the production of fungicides fumonisin, isoxaflutole, vinblastine and myclobutanil.

Preparation

synthesis of 3,5-Dichloroaniline: Add 25% hydrochloric acid and o-nitroaniline in the reaction kettle, turn on the stirring, pass chlorine gas for chlorination at 10-20℃ and negative pressure, after passing chlorine gas, continue to stir for 15min, then filter, and wash the filter cake with water to neutral, that is, 2,4-dichloro-6-nitroaniline.
In another reaction kettle add industrial ethanol, under stirring, then add 2,4-dichloro-6-nitroaniline, add 95% H2SO4 below 40°C, cool to 15°C, add sodium nitrite in batches, after adding sodium nitrite, continue to hold the reaction at 15°C for 4h, then put the material into denitration kettle, slowly heat to reflux temperature 80°C and keep reflux for 2h, then raise the temperature to evaporate ethanol, and then distill the ethanol. Liquid material into the distillation kettle for water distillation, distillation of the resulting oil and water material for stratification, to obtain 3,5-dichloronitrobenzene.
Put a certain amount of water and 3,5-dichloronitrobenzene in the reaction kettle, raise the temperature to reflux under stirring, add a certain concentration of sodium disulfide solution drop by drop in 1h, and keep reflux for 3h, rest stratification, the lower layer of oily material washed with hot water to obtain 3,5-dichloroaniline.

Definition

ChEBI: 3,5-dichloroaniline is a dichloroaniline.

3,5-Dichloroaniline Preparation Products And Raw materials

Raw materials

2,4-DICHLORO-6-NITROANILINE 2-Nitroaniline 3,5-Dichloronitrobenzene Ethanol solution Sodium disulfide p-Dichlorobenzene 1-Bromo-3,5-dichlorobenzene 3,5-dichlorobenzamide Industrial ethanol 1,3,5-Trichlorobenzene 1,2-Dichlorobenzene 2,6-Dichloroaniline 4-Nitroaniline 2,6-Dichloro-4-nitroaniline

Preparation Products

Dimethachlon Procymidone Chlorfluazuron Iprodione VINCLOZOLIN 3,5-Dichlorophenyl isocyanate 2,4-Difluoro-3,5-dichloroaniline Teflubenzuron 1-(3,5-DICHLOROPHENYL)PIPERAZINE
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3,5-Dichloroaniline Suppliers

Americas 1 Belgium 4 Canada 2 China 251 Europe 3 France 1 Germany 12 India 30 Indonesia 1 Japan 8 Slovakia 1 South Africa 1 Switzerland 3 The Netherlands 1 Ukraine 2 United Kingdom 18 United States 45 Global 384
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View Lastest Price from 3,5-Dichloroaniline manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
3,5-dichloroaniline 626-43-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-08-19
Qingdao RENAS Polymer Material Co., Ltd.
Product
3,5-Dichloroaniline 626-43-7
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2024-08-30
Career Henan Chemical Co
Product
3,5-Dichloroaniline 626-43-7
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-15

626-43-7, 3,5-DichloroanilineRelated Search:

4-Chloroaniline 3-Chloroaniline 2-Chloroaniline DICHLORPHENAMIDE BULK POWDER 3,4-Dichloroaniline 4-Amino-2,6-dichlorophenol 2,4-DICHLORO-6-NITROANILINE 2,6-Dichloro-4-nitrophenol Pentachloroaniline 2,3,5,6-TETRACHLOROANILINE 2,5-Dichloroaniline 2,6-Dichloroaniline 3,5-Dichlorophenyl isocyanate 3,5-Dichloronitrobenzene 2,3,4,5-Tetrachloronitrobenzene 2,4-Dichloroaniline 1,5-DICHLORO-2,3-DINITROBENZENE 2,3-Dichloroaniline

  • 3,5-DCA
  • 3,5-dichloro
  • 3,5-dichloro-anilin
  • 3,5-dichloro-benzenamin
  • Aniline, 3,5-dichloro-
  • Benzenamine,3,5-dichloro-
  • BF352-31
  • m-Dichloroaniline
  • TIMTEC-BB SBB008349
  • 3,5-DICHLORO BENZENAMINE
  • 3,5-DICHLOROANILINE
  • 3,5 DICHLORANILINE
  • AKOS BBS-00003558
  • DICHLOROANILINE(3,5)
  • LABOTEST-BB LTBB000733
  • 2,6-DICHLOROBENZOIC ACID PESTANAL
  • 3,5-Dichloroaniline,DCA
  • 3,5-Dichloroaniline,98%
  • 1-AMINO-3,5-DICHLORO-BENZENE
  • DICHLORO-3,5-ANILINE
  • 3,5-Dichlorophenylamine
  • 5-Amino-1,3-dichlorobenzene
  • 3,5-Dichloroaniline Solution, 100ppm
  • 3,5-Dichloroaniline &gt
  • 3,5-DichloroanilineSolution,1000mg/L,1ml
  • 3,5-DICHLOROANILINE FOR SYNTHESIS
  • 3,5-Dichloranilin
  • 3,5-Dichloroaniline Solution in Toluene, 100μg/mL
  • 3,5-Dichloroaniline ISO 9001：2015 REACH
  • Phloroglucinol Impurity 26
  • Phloroglucinol EP Impurity L
  • 3,5-Dichloroaniline in methanol
  • 3,5-Dichloroaniline 100 μg/ml Methanol
  • C12323500 3,5-Dichloroaniline
  • XA12323500ME3,5-DichloroanilinE100μg/mLin Me
  • Phloroglucinol Impurity 26 (Phloroglucinol EP Impurity L)
  • 3,5-Dichloroaniline 100 μg/mL in Methanol
  • 3,5-dichloroaniline - [AC78542]
  • 626-43-7
  • 1798-08-1
  • 6078-60-4
  • Building Blocks
  • Amines
  • Organic Building Blocks
  • Nitrogen Compounds
  • C2 to C6
  • Anilines, Aromatic Amines and Nitro Compounds
  • Amines
  • C2 to C6
  • Nitrogen Compounds
  • Alpha sort
  • AromaticsPesticides&Metabolites
  • Chemical Class
  • D
  • DAlphabetic
  • DIA - DIC