ChemicalBook > CAS DataBase List > 1,3,5-Trichlorobenzene

1,3,5-Trichlorobenzene

Product Name
1,3,5-Trichlorobenzene
CAS No.
108-70-3
Chemical Name
1,3,5-Trichlorobenzene
Synonyms
TCB;Trichlorobenzene;1,3,5-TCB;ai3-22031;1.3.5-Tric;1,3,5-TrichL;s-Trichlorobenzene;1,3,5-Trichlorbenzol;SYM-TRICHLOROBENZENE;1,3,5-Trichlorobenze
CBNumber
CB8852759
Molecular Formula
C6H3Cl3
Formula Weight
181.45
MOL File
108-70-3.mol
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1,3,5-Trichlorobenzene Property

Melting point:
63 °C
Boiling point:
208 °C(lit.)
Density 
1.4528 (estimate)
vapor pressure 
0.58 at 25 °C (quoted, Mackay et al., 1982)
refractive index 
1.5693 (estimate)
Flash point:
260 °F
storage temp. 
0-6°C
solubility 
Soluble in benzene, ether, ligroin (Weast, 1986), glacial acetic acid, carbon disulfide, and petroleum ether (Windholz et al., 1983)
form 
powder or crystals
color 
Off-White
Water Solubility 
Insoluble in water.
Merck 
14,9632
BRN 
1635233
Henry's Law Constant
1.83, 2.04, 2.64, 4.49, and 5.24 at 2.0, 6.0, 10.0, 18.0, and 25.0 °C, respectively (EPICS-SPME, Dewulf et al., 1999)
Stability:
Stable. Incompatible with acids, strong oxidizing agents.
LogP
4.190
CAS DataBase Reference
108-70-3(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1,3,5-trichloro-(108-70-3)
EPA Substance Registry System
1,3,5-Trichlorobenzene (108-70-3)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38-38-22-52/53
Safety Statements 
26-36-36/37-61
RIDADR 
3077
WGK Germany 
3
RTECS 
DC2100100
Hazard Note 
Harmful/Irritant
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
29039990
Hazardous Substances Data
108-70-3(Hazardous Substances Data)
Toxicity
Drinking water standard: No MCLGs or MCLs have been proposed, however, a DWEL of 200 μg/L was recommended (U.S. EPA, 2000).
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T54607
Product name
1,3,5-Trichlorobenzene
Purity
99%
Packaging
100g
Price
$80.1
Updated
2024/03/01
Sigma-Aldrich
Product number
03824
Product name
1,3,5-Trichlorobenzene
Purity
certified reference material, TraceCERT
Packaging
100mg
Price
$119
Updated
2024/03/01
Alfa Aesar
Product number
L02132
Product name
1,3,5-Trichlorobenzene, 98%
Packaging
50g
Price
$42.1
Updated
2023/06/20
Usbiological
Product number
411208
Product name
1,3,5-Trichlorobenzene
Packaging
250mg
Price
$403
Updated
2021/12/16
TRC
Product number
T773790
Product name
1,3,5-Trichlorobenzene
Packaging
1g
Price
$405
Updated
2021/12/16
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1,3,5-Trichlorobenzene Chemical Properties,Usage,Production

Description

Trichlorobenzenes (TCBs) are synthetic chemicals that occur in three different isomeric forms. The three chlorinated cyclic aromatic isomers are 1,2,3-trichlorobenzene (1,2,3-TCB), 1,2,4-trichlorobenzene (1,2,4-TCB), and 1,3,5-trichlorobenzene (1,3,5-TCB). 1,2,4-TCB is one of the 188 chemicals designated as a hazardous air pollutant under the Clean Air Act.

Chemical Properties

white to beige crystalline powder

Uses

1,3,5-Trichlorobenzene is used for someof these applications plus as a termite preparation and insecticide. These compounds are found as unintended by-products of the manufacture of the mono- and dichlorobenzenes.

Uses

Trichlorobenzenes are primarily used as solvents in chemical manufacturing industries. 1,2,4-Trichlorobenzene is economically the most important isomer. 1,2,4-Trichlorobenzene is used as a solvent in chemical reactions to dissolve oils, waxes, and resins. Furthermore, it is also used as a dye carrier. 1,2,3- Trichlorobenzene is used as an intermediate for pesticides production, pigments, and dyes. 1,3,5-Trichlorobenzene is not marketed commercially and has very limited use as a chemical intermediate. Besides, trichlorobenzenes can also be used as degreasing agents, as septic tanks and drain cleaners, and as an ingredient in wood preservatives and abrasive formulations. Other minor uses include metal work, anticorrosive paint, and corrosion inhibitor in sprays. In the past, mixed isomers of trichlorobenzenes were used to control termites; however, their use has been discontinued.

Uses

1,3,5-Trichlorobenzene is an isomer of 1,2,4-Trichlorobenzene (T774220) which is a solvent in various organic chemical reactions.

Definition

ChEBI: 1,3,5-trichlorobenzene is a trichlorobenzene carrying chloro substituents at positions 1, 3 and 5.

General Description

White to off-white crystals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Can react vigorously with oxidizing materials. .

Fire Hazard

1,3,5-Trichlorobenzene is combustible.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits toxic vapors of Cl-.

Environmental Fate

Biological. Under aerobic conditions, soil microbes degraded 1,3,5-trichlorobenzene to 1,3- and 1,4-dichlorobenzene and carbon dioxide (Kobayashi and Rittman, 1982). A mixed culture of soil bacteria or a Pseudomonas sp. transformed 1,3,5-trichlorobenzene to 2,4,6-trichlorophenol (Ballschiter and Scholz, 1980).
In an enrichment culture derived from a contaminated site in Bayou d’Inde, LA, 1,3,5- trichlorobenzene underwent reductive dechlorination yielding 1,3-dichlorobenzene. The maximum dechlorination rate, based on the recommended Michaelis-Menten model, was 9.5 nM/d (Pavlostathis and Prytula, 2000).
Photolytic. The sunlight irradiation of 1,3,5-trichlorobenzene (20 g) in a 100-mL borosilicate glass-stoppered Erlenmeyer flask for 56 d yielded 160 ppm pentachlorobiphenyl (Uyeta et al., 1976). A photooxidation half-life of 6.17 months was reported for the vapor-phase reaction of 1,3,5-trichlorobenzene with OH radicals (Atkinson, 1985).

Purification Methods

Recrystallise it from dry *benzene or toluene. [Beilstein 5 IV 666.]

Toxicity evaluation

The liver is themain target of trichlorobenzenes irrespective of the route of exposure. The mechanisms of liver toxicity induced by these chemicals have not been illustrated. It might involve intermediate arene oxides formed during initial transformation to trichlorophenols. In addition, exposure to 1,2,4-TCB induced porphyria in rats by inducing daminolevulinic acid (ALA) synthetase, a rate-limiting enzyme in the biosynthesis of heme, and also heme oxygenase, a ratelimiting enzyme in the degradation of heme synthetase, and therefore increasing heme production.

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1,3,5-Trichlorobenzene Suppliers

Hebei mo Jin biotechnology co., ltd
Tel
15097329902
Fax
18503279000
Email
sales@hebeimojin.com
Country
China
ProdList
1576
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12438
Advantage
60
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
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View Lastest Price from 1,3,5-Trichlorobenzene manufacturers

Changde Changlian Chemical Co., Ltd.
Product
1,3,5-Trichlorobenzene 108-70-3
Price
US $0.00/Kg/Drum
Min. Order
25Kg/Drum
Purity
99
Supply Ability
1mt
Release date
2020-10-21
Ningxia Jinhua Chemical Co.,Ltd
Product
1,3,5-Trichlorobenzene 108-70-3
Price
US $0.00/Kg/Drum
Min. Order
25Kg/Drum
Purity
99
Supply Ability
1mt
Release date
2020-10-21
Yancheng Green Chemicals Co.,Ltd
Product
1,3,5-Trichlorobenzene 108-70-3
Price
US $0.00/KG
Min. Order
25KG
Purity
99
Supply Ability
1mt
Release date
2020-10-21

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