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5-Amino-2-methoxyphenol

Product Name
5-Amino-2-methoxyphenol
CAS No.
1687-53-2
Chemical Name
5-Amino-2-methoxyphenol
Synonyms
5-AMINOGUAIACOL;TIMTEC-BB SBB007884;5-Aminoguaiacol, Tech;3-hydroxy-p-anisidine;5-AMINO-2-METHOXYPHENOL;2-METHOXY-5-AMINOPHENOL;5-Amino-2-Methyoxyphenol;3-HYDROXY-4-METHOXYANILINE;Phenol, 5-amino-2-methoxy-;5-AMINO-2-METHOXYPHENOL 99%
CBNumber
CB9403833
Molecular Formula
C7H9NO2
Formula Weight
139.15
MOL File
1687-53-2.mol
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5-Amino-2-methoxyphenol Property

Melting point:
130-132 °C(lit.)
Boiling point:
255.1°C (rough estimate)
Density 
1.1997 (rough estimate)
refractive index 
1.4800 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
slightly soluble
pka
10.02±0.10(Predicted)
form 
powder to crystal
color 
Light yellow to Amber to Dark green
Water Solubility 
slightly soluble
BRN 
2717084
InChI
InChI=1S/C7H9NO2/c1-10-7-3-2-5(8)4-6(7)9/h2-4,9H,8H2,1H3
InChIKey
BLQFHJKRTDIZLX-UHFFFAOYSA-N
SMILES
C1(O)=CC(N)=CC=C1OC
CAS DataBase Reference
1687-53-2(CAS DataBase Reference)
NIST Chemistry Reference
5-Amino-2-methoxyphenol(1687-53-2)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38-20/22
Safety Statements 
26-36-37/39
RIDADR 
2811
WGK Germany 
3
PackingGroup 
II
HS Code 
29225000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
262110
Product name
5-Amino-2-methoxyphenol
Purity
98%
Packaging
1g
Price
$41.5
Updated
2023/06/20
Sigma-Aldrich
Product number
262110
Product name
5-Amino-2-methoxyphenol
Purity
98%
Packaging
10g
Price
$197
Updated
2023/06/20
TCI Chemical
Product number
H0634
Product name
3-Hydroxy-4-methoxyaniline
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$24
Updated
2025/07/31
TCI Chemical
Product number
H0634
Product name
3-Hydroxy-4-methoxyaniline
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$97
Updated
2025/07/31
TRC
Product number
A634785
Product name
5-Amino-2-methoxyphenol
Packaging
500mg
Price
$60
Updated
2021/12/16
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5-Amino-2-methoxyphenol Chemical Properties,Usage,Production

Chemical Properties

grey-brown to dark brown crystalline powder

General Description

5-Amino-2-methoxyphenol reacts with ninhydrin to yield tetrahydroindeno[1,2-b]indolones.

Synthesis

636-93-1

1687-53-2

Commercially available 2-methoxy-5-nitrophenol (40 g, 236.5 mmol) was dissolved in methanol (300 mL) under argon protection and palladium/carbon catalyst (3 g) was added. The suspension was vacuum degassed and purged repeatedly with hydrogen several times. Subsequently, the reaction mixture was stirred at room temperature under hydrogen pressure (40 psi) for 24 hours. After completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the intermediate 2-methoxy-5-aminophenol (25 g, 76% yield) as a yellow solid. Electrospray ionization mass spectrometry (ESI-MS) showed [M + 1] peak of 140.1, which was consistent with the calculated value. Elemental analysis (C7H9NO2) calculated value: 139.06.

References

[1] Patent: WO2015/192981, 2015, A1. Location in patent: Page/Page column 71-72
[2] Gazzetta Chimica Italiana, 1907, vol. 37 II, p. 372
[3] Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1912, vol. <5> 21 II, p. 207
[4] Journal of the American Chemical Society, 1948, vol. 70, p. 168,170
[5] Journal of the Chemical Society, 1951, p. 2426,2429

5-Amino-2-methoxyphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Amino-2-methoxyphenol Suppliers

Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
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View Lastest Price from 5-Amino-2-methoxyphenol manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
5-Amino-2-methoxyphenol 1687-53-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-28
Henan Aochuang Chemical Co.,Ltd.
Product
5-Amino-2-methoxyphenol 1687-53-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Hebei Yanxi Chemical Co., Ltd.
Product
5-Amino-2-methoxyphenol 1687-53-2
Price
US $20.00-1.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-25

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