ChemicalBook > CAS DataBase List > N-METHOXYCARBONYLMALEIMIDE

N-METHOXYCARBONYLMALEIMIDE

Product Name: N-METHOXYCARBONYLMALEIMIDE
CAS No.: 55750-48-6
Chemical Name: N-METHOXYCARBONYLMALEIMIDE
Synonyms: Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate;methyl 2,5-dioxopyrrole-1-carboxylate;Methyl 2,5-dioxo-2H-pyrrole-1(5H)-carboxylate;106271;Einecs 259-792-3;N-(CarboMethoxy)MaleiMide;N-METHOXYCARBONYLMALEIMIDE;N-Methoxycarbonylmaleimide>N-methoxycarbonylmaleimide 98%;N-methyoxy carbonyl maleimide 97%
CBNumber: CB9424977
Molecular Formula: C6H5NO4
Formula Weight: 155.11
MOL File: 55750-48-6.mol

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N-METHOXYCARBONYLMALEIMIDE Property

Melting point:: 63-65 °C
Boiling point:: 242.5±23.0 °C(Predicted)
Density: 1.496±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: DMSO (Slightly), Ethyl Acetate (Slightly), Chloroform
form: Solid
pka: -3.17±0.20(Predicted)
color: Off-White to Pink
BRN: 1450638
InChI: InChI=1S/C6H5NO4/c1-11-6(10)7-4(8)2-3-5(7)9/h2-3H,1H3
InChIKey: LLAZQXZGAVBLRX-UHFFFAOYSA-N
SMILES: N1(C(OC)=O)C(=O)C=CC1=O

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10
HS Code: 29251900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2333
Product name: N-Methoxycarbonylmaleimide
Purity: >98.0%(N)
Packaging: 1g
Price: $75
Updated: 2025/07/31

TCI Chemical

Product number: M2333
Product name: N-Methoxycarbonylmaleimide
Purity: >98.0%(N)
Packaging: 5g
Price: $262
Updated: 2025/07/31

TRC

Product number: M261300
Product name: N-(Methoxycarbonyl)Maleimide
Packaging: 2g
Price: $115
Updated: 2021/12/16

BroadPharm

Product number: BP-21525
Product name: methyl2,5-dioxo-2H-pyrrole-1(5H)-carboxylate
Packaging: 1g
Price: $72
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-0JK
Product name: N-Methoxycarbonylmaleimide
Packaging: 1g
Price: $120
Updated: 2021/12/16

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N-METHOXYCARBONYLMALEIMIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White Cyrstalline Solid

Uses

N-(Methoxycarbonyl) Maleimide (cas# 55750-48-6) is a compound useful in organic synthesis.

Synthesis

541-59-3

79-22-1

55750-48-6

To a solution of ethyl acetate (120 mL) of maleimide (6.35 g, 65.4 mmol) was sequentially added N-methylmorpholine (NMM, 8.6 mL, 78.5 mmol) and methyl chloroformate (6.0 mL, 78.5 mmol) at 0 °C. The reaction mixture was stirred at 0 °C for 30 min, then brought to room temperature and continued stirring for 1 h. The reaction was completed by filtration. Upon completion of the reaction, the solid was collected by filtration and the filtrate was concentrated under reduced pressure. The concentrated residue was dissolved in dichloromethane, filtered through a silica gel column and eluted with dichloromethane to remove red impurities. The eluate was concentrated and the resulting solid was ground with a solvent mixture of ethyl acetate and petroleum ether to give a final white solid of methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate (9.0 g, 88% yield).

References

[1] Chemistry Letters, 2012, vol. 41, # 3, p. 313 - 315
[2] Journal of Medicinal Chemistry, 2013, vol. 56, # 20, p. 7890 - 7901
[3] Patent: WO2017/46658, 2017, A1. Location in patent: Page/Page column 149; 150
[4] Journal of Fluorine Chemistry, 2013, vol. 152, p. 173 - 181
[5] Journal of the American Chemical Society, 2008, vol. 130, # 34, p. 11288 - 11289

N-METHOXYCARBONYLMALEIMIDE Preparation Products And Raw materials

Raw materials

Maleimide Methyl chloroformate Ethyl acetate PETROLEUM ETHER

Preparation Products

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View Lastest Price from N-METHOXYCARBONYLMALEIMIDE manufacturers

Career Henan Chemical Co

Product: N-METHOXYCARBONYLMALEIMIDE 55750-48-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 200KG
Release date: 2019-08-30

55750-48-6, N-METHOXYCARBONYLMALEIMIDERelated Search:

N,N'-Ethylenebis(stearamide) (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride N-Ethylmaleimide N-Methoxyphthalimide N-(Hydroxymethyl)phthalimide N-Cyclohexylmaleimide Maleamic acid (2,5-dioxo-2,5-dihydro-pyrrol-1-yl)acetic acid Methyl ester N-Allylmaleimide N-CARBAMOYLMALEIMIDE N-CARBAMOYLMALEAMIC ACID N-Phenylmaleimide N-MALEIMIDOMETHANOL ACETYLDIFORMAMIDE N-METHOXYCARBONYLMALEIMIDE N-Methylolacrylamide N,N-DIFORMYLFORMAMIDE tert-butyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate

N-METHOXYCARBONYLMALEIMIDE

106271

methyl 2,5-dihydro-2,5-dioxo-1H-pyrrole-1-carboxylate

2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-carboxylic acid methyl ester

2,5-Dioxo-2,5-dihydro-1H-pyrrole-1-carboxylic acid methyl ester

2,5-Dioxo-3-pyrroline-1-carboxylic acid methyl ester

Einecs 259-792-3

N-(CarboMethoxy)MaleiMide

1H-Pyrrole-1-carboxylic acid, 2,5-dihydro-2,5-dioxo-, Methyl ester

Methyl 2,5-dioxo-2H-pyrrole-1(5H)-carboxylate

N-MethoxycarbonylMaleiMide >=97.0% (N)

N-methoxycarbonylmaleimide 98%

Methyl 2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate

N-Methoxycarbonylmaleimide≥ 98%(N)

N-methyoxy carbonyl maleimide 97%

methyl 2,5-dioxopyrrole-1-carboxylate

2,5-Dioxo-3-pyrroline-1-carboxylic acid methyl

N-Methoxycarbonylmaleimide&gt

<i>N</i>-Methoxycarbonylmaleimide

55750-48-6

Carbonyl Compounds

Building Blocks

Organic Building Blocks

Cyclic Imides

Building Blocks

Carbonyl Compounds

Chemical Synthesis

Cyclic Imides

Organic Building Blocks

Life Science Chemical Reagents

Nitric Oxide Reagents

Cross Linking Reagents

Maleimide Derivatives

MTS & Sulfhydryl Active Reagents

Carbonyl Compounds

Cyclic Imides

Organic Building Blocks