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Chelidonic acid

Configuration Method
Product Name
Chelidonic acid
CAS No.
99-32-1
Chemical Name
Chelidonic acid
Synonyms
AI3-19253;JERVA ACID;γ-Pyrone-2;jervaicacid;compoundxi*;JERVASIC ACID;AKOS AUF02028;CHELIDONIC ACID;Chelidonic acid 98%;TIMTEC-BB SBB000242
CBNumber
CB9441381
Molecular Formula
C7H4O6
Formula Weight
184.1
MOL File
99-32-1.mol
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Chelidonic acid Property

Melting point:
265 °C (dec.) (lit.)
Boiling point:
238.02°C (rough estimate)
Density 
1.4880 (rough estimate)
refractive index 
1.5600 (estimate)
storage temp. 
2-8°C
solubility 
DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
form 
Solid
pka
1.26±0.40(Predicted)
color 
Gray to brown
Water Solubility 
14.3g/L(25 ºC)
Merck 
13,2060
BRN 
163607
InChIKey
PBAYDYUZOSNJGU-UHFFFAOYSA-N
LogP
-0.746 (est)
CAS DataBase Reference
99-32-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
UP7350000
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
382272
Product name
Chelidonic acid
Purity
98%
Packaging
5g
Price
$193
Updated
2024/03/01
Sigma-Aldrich
Product number
382272
Product name
Chelidonic acid
Purity
98%
Packaging
25g
Price
$244.8
Updated
2024/03/01
TRC
Product number
E588808
Product name
4-Oxo-4h-pyran-2,6-dicarboxylicAcid
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
E588808
Product name
4-Oxo-4h-pyran-2,6-dicarboxylicAcid
Packaging
500mg
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-W022229
Product name
Chelidonic acid
Purity
>97.0%
Packaging
10g
Price
$78
Updated
2021/12/16
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Chelidonic acid Chemical Properties,Usage,Production

Configuration Method

Chelidonic acid is supplied as a crystalline solid. A stock solution may be made by dissolving thechelidonic acid in the solvent of choice, which should be purged with an inert gas. Chelidonic acid is soluble in the organic solvent DMSO at approximately 1 mg/ml concentration. Chelidonic acid is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers,chelidonic acid should first be dissolved in DMSO and then diluted with the aqueous buffer of choice. Chelidonic acid has a solubility of approximately 0.14 mg/ml in a 1:6 solution of DMSO: PBS(pH 7.2) using this method. We do not recommend storing the aqueous solution for more than one day.

Uses

Chelidonic acid is suitable for use a in homogeneous preparation of native dihydrodipicolinate synthase from pea. It may be used as endocyclic oxygen-containing ligand in the synthesis of aqua[bis(2-pyridylmethyl)amine][chelidonato(1.5-)]-copper(II) chelidonate(0.5-) monohydrate.

Definition

ChEBI: Chelidonic acid is a carbonyl compound and a member of pyrans.

General Description

Chelidonic acid (CA) is a γ-pyrone. It is reported as constituent of the rhizome of Chelidonium majus L. It has many pharmacological effects, such as mild analgesic and antimicrobial effects. Therapeutic potential of CA for the treatment of intestinal inflammation has been investigated. CA is reported as inhibitor of the rat brain glutamate decarboxylase. Biosynthesis of CA in cell suspension cultures of Leucojum aestivum has been studied.

Purification Methods

The acid crystallises from aqueous EtOH. Dry it first at 100o/2hours, then at 160o to constant weight to remove water of crystallisation. It decarboxylates at 220-230o in a vacuum. [Riegel & Zwilgmeyer Org Synth Coll Vol II 126 1943, Beilstein 18 H 490, 18/8 V 646.]

Chelidonic acid Preparation Products And Raw materials

Raw materials

Diethyl oxalate

Preparation Products

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Chelidonic acid Suppliers

China 161 France 1 Germany 5 India 3 Switzerland 1 United Kingdom 7 United States 27 Global 205
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View Lastest Price from Chelidonic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Chelidonic acid 99-32-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000KG
Release date
2024-08-25
Honest Joy Holdings Limited
Product
4-oxo-4H-pyran-2,6-dicarboxylic acid 99-32-1
Price
US $0.00/KG
Min. Order
1KG
Purity
98.8%
Supply Ability
100 tons
Release date
2022-02-18
Nanjing jinheyou Trading Co., Ltd.
Product
Chelidonic acid 99-32-1
Price
US $0.00/g
Min. Order
1g
Purity
99.5%min
Supply Ability
20kg/week
Release date
2019-10-28

99-32-1, Chelidonic acidRelated Search:

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  • 4-Oxopyran-2,6-dicarboxylic acid
  • 4-Pyranone-2,6-dicarboxylic acid
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  • CHELIDONIC ACID
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  • JERVA ACID
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  • AKOS AUF02028
  • TIMTEC-BB SBB000242
  • 4-oxo-1,4-pyran-2,6-dicarboxylicacid
  • 4-oxo-4h-pyran-6-dicarboxylicacid
  • 6-dicarboxylicacid,4-oxo-4H-Pyran-2
  • CHELIDONIC ACID, ANHYDROUS
  • AI3-19253
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  • PYRAN-2,6-DICARBOXYLICACID,4-OXO-
  • γ-Pyrone-2
  • γ-Pyrone-2,6-dicarboxylic acid
  • 99-32-1
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