Ethyl 1-benzylpyrrolidine-3-carboxylate
- Product Name
- Ethyl 1-benzylpyrrolidine-3-carboxylate
- CAS No.
- 5747-92-2
- Chemical Name
- Ethyl 1-benzylpyrrolidine-3-carboxylate
- Synonyms
- ETHYL 1 -BENZYL-PYRROLIDINE-3-CALATE;ETHYL 1-BENZYL-PYRROLIDINE-3-CARBOXYLATE;Ethyl1-benzylpyrrolidine-3-carboxylate,97%;1-BENZYL-PYRROLIDINE-3-CARBOXYLIC ACID ETHYL ESTER;3-Pyrrolidinecarboxylic acid, 1-(phenylMethyl)-, ethyl ester
- CBNumber
- CB9450640
- Molecular Formula
- C14H19NO2
- Formula Weight
- 233.31
- MOL File
- 5747-92-2.mol
Ethyl 1-benzylpyrrolidine-3-carboxylate Property
- Boiling point:
- 118-120 °C(Press: 0.75 Torr)
- Density
- 1.099±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- Liquid
- pka
- 8.43±0.40(Predicted)
- color
- Pale yellow
- InChI
- InChI=1S/C14H19NO2/c1-2-17-14(16)13-8-9-15(11-13)10-12-6-4-3-5-7-12/h3-7,13H,2,8-11H2,1H3
- InChIKey
- CYPXEPWPTXKUPL-UHFFFAOYSA-N
- SMILES
- N1(CC2=CC=CC=C2)CCC(C(OCC)=O)C1
- CAS DataBase Reference
- 5747-92-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-25
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
- HazardClass
- IRRITANT
N-Bromosuccinimide Price
- Product number
- ADE000011
- Product name
- Ethyl 1-benzyl-pyrrolidine-3-carboxylate
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $201
- Updated
- 2023/06/20
- Product number
- 448647
- Product name
- Ethyl 1-benzylpyrrolidine-3-carboxylate
- Packaging
- 100mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- E900003
- Product name
- Ethyl 1-benzyl-pyrrolidine-3-carboxylate
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FB34113
- Product name
- 1-Benzyl-pyrrolidine-3-carboxylic acid ethyl ester
- Packaging
- 1g
- Price
- $72
- Updated
- 2021/12/16
- Product number
- J94957
- Product name
- 1-Benzyl-pyrrolidine-3-carboxylicacidethylester
- Packaging
- 5g
- Price
- $75
- Updated
- 2021/12/16
Ethyl 1-benzylpyrrolidine-3-carboxylate Chemical Properties,Usage,Production
Uses
Ethyl 1-benzylpyrrolidine-3-carboxylate
Synthesis
64-17-5
10603-52-8
5747-92-2
General procedure for the synthesis of ethyl 1-benzylpyrrolidine-3-carboxylate from ethanol and 1-benzylpyrrolidine-3-carbonitrile: A solution of 1-benzylpyrrolidine-3-carbonitrile (1.5 g, 7.9 mmol) in ethanol (40 mL) was treated with a dioxane solution (20 mL) in 4 M HCl and stirred overnight at room temperature. Upon completion of the reaction, the reaction mixture was cooled to 0 °C and the pH was adjusted to neutral with saturated aqueous NaHCO3 solution, followed by extraction with ethyl acetate (EtOAc). The organic layers were combined, dried with anhydrous Na2SO4 and concentrated under reduced pressure. Purification by fast column chromatography (eluent: 35-50% EtOAc/hexane) afforded ethyl 1-benzylpyrrolidine-3-carboxylate (1.1 g, 58% yield).
References
[1] Patent: WO2003/103669, 2003, A1. Location in patent: Page 71-72
Ethyl 1-benzylpyrrolidine-3-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Ethyl 1-benzylpyrrolidine-3-carboxylate Suppliers
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View Lastest Price from Ethyl 1-benzylpyrrolidine-3-carboxylate manufacturers
- Product
- Ethyl 1-benzylpyrrolidine-3-carboxylate 5747-92-2
- Price
- US $0.00-0.00/g
- Min. Order
- 100g
- Purity
- 97%
- Supply Ability
- 500kg/M
- Release date
- 2024-11-07
- Product
- Ethyl 1-benzylpyrrolidine-3-carboxylate 5747-92-2
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 98%;99%
- Supply Ability
- 1kg； 5kg；10kg；25kg
- Release date
- 2020-01-07