(TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL

Product Name: (TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL
CAS No.: 102229-10-7
Chemical Name: (TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL
Synonyms: 2-(tert-Butyldimethylsiloxy)ethanol;DK025;DK448;DKSI011;CB9511523;DKFELEX0097;2-(t-butyldimethylsiloxy)ethanol;2-tert-Butyldimethylsilyloxyethanol;(TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL;2-((tert-ButyldiMethylsilyl)oxy)etanol-
CBNumber: CB9511523
Molecular Formula: C8H20O2Si
Formula Weight: 176.33
MOL File: 102229-10-7.mol

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(TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL Property

Boiling point:: 74-80℃ (17 Torr)
Density: 0.890
refractive index: 1.430
storage temp.: 2-8°C
solubility: Dichloromethane (Slightly), Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate
form: clear liquid
pka: 14.38±0.10(Predicted)
Specific Gravity: 0.8908
color: Colorless to Almost colorless
Hydrolytic Sensitivity: 7: reacts slowly with moisture/water
Stability:: Acid Sensitive
InChI: InChI=1S/C8H20O2Si/c1-8(2,3)11(4,5)10-7-6-9/h9H,6-7H2,1-5H3
InChIKey: YJYAGNPMQVHYAH-UHFFFAOYSA-N
SMILES: C(O)CO[Si](C(C)(C)C)(C)C

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Safety

RIDADR: 1993
HazardClass: 3
PackingGroup: Ⅲ
HS Code: 2931900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5851
Product name: 2-[[tert-Butyl(dimethyl)silyl]oxy]ethanol
Packaging: 25G
Price: $111
Updated: 2025/07/31

TCI Chemical

Product number: B5851
Product name: 2-[[tert-Butyl(dimethyl)silyl]oxy]ethanol
Packaging: 100G
Price: $334
Updated: 2025/07/31

TRC

Product number: B691470
Product name: 2-tert-Butyldimethylsilyloxyethanol
Packaging: 1g
Price: $110
Updated: 2021/12/16

TRC

Product number: B691470
Product name: 2-tert-Butyldimethylsilyloxyethanol
Packaging: 25g
Price: $250
Updated: 2021/12/16

Apolloscientific

Product number: OR931367
Product name: 2-((tert-Butyldimethylsilyl)oxy)ethanol
Purity: 97%
Packaging: 25g
Price: $327
Updated: 2021/12/16

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(TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL Chemical Properties,Usage,Production

Chemical Properties

Oil

Uses

(Tert.-Butyldimethylsilyloxy)Ethanol (also known as 2-((tert-Butyldimethylsilyl)oxy)ethanol) is used in organic synthesis to prepare other silane compounds.

Synthesis

107-21-1

18162-48-6

102229-10-7

A solution of anhydrous THF (100 mL) with ethylene glycol (20.0 g, 0.322 mol) was added slowly and dropwise to an anhydrous THF (500 mL) suspension of NaH (12.9 g, 0.322 mol, 60% dispersed in mineral oil). After stirring the reaction mixture for 1 h at room temperature, tert-butyldimethylchlorosilane (TBSCl, 48.59 g, 0.322 mol) was added and stirring was continued for 1 h at room temperature. Upon completion of the reaction, the reaction was quenched with 10% aqueous K2CO3 (100 mL) and subsequently extracted with methyl tert-butyl ether (MTBE, 3 x 300 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with gradient elution using a petroleum ether solution of 1% to 33% ethyl acetate to afford 2-((tert-butyldimethylmethylsilyl)oxy)ethanol (55.0 g, 96% yield) as a colorless oil.

References

[1] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 7, p. 2375 - 2385
[2] Organic Letters, 2016, vol. 18, # 18, p. 4534 - 4537
[3] Patent: US2016/122318, 2016, A1. Location in patent: Paragraph 0181
[4] Patent: WO2017/24018, 2017, A1. Location in patent: Paragraph 00131
[5] Journal of Medicinal Chemistry, 2007, vol. 50, # 9, p. 2157 - 2165

(TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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(TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL Suppliers

Americas 1 Canada 1 China 175 Europe 1 Germany 1 India 5 Japan 1 United States 10 Global 195

Shanghai Gileader Advanced Material Technology Co.,Ltd

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Suzhou Highfine Biotech Co., Ltd

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View Lastest Price from (TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2-[(tert-Butyldimethylsilyl)oxy]ethanol 102229-10-7
Price: US $1.10-9.90/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 100kg
Release date: 2025-08-18

Shaanxi Dideu New Materials Co. Ltd

Product: (TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL 102229-10-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 95.0%
Supply Ability: 10000KGS
Release date: 2025-07-07

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-(t-butyldimethylsiloxy)ethanol 102229-10-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

102229-10-7, (TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOLRelated Search:

tert-Butylchlorodiphenylsilane ALLYL(CHLOROMETHYL)DIMETHYLSILANE CHLOROMETHYL(METHYL)DIMETHOXYSILANE TERT-BUTYLDIMETHYL(2-PROPYNYLOXY)SILANE tert-Butyl N-(3-aminopropyl)-N-methylcarbamate TERT-BUTYL 3-(4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOL-1-YL)AZETIDINE-1-CARBOXYLATE TERT-BUTYL PROPIOLATE tert-Butyldiphenylsilane TERT-BUTYL-(2-IODO-ETHOXY)-DIMETHYL-SILANE 2-(N-Boc-aMinoMethyl)-5-chloropyridine 5-O-tert-Butyldiphenylsilyl-2,3-O-isopropylidene-D-ribofuranose DMT-2′O-TBDMS-rU Phosphoramidite DMT-2'O-TBDMS-rA(bz) Phosphoramidite 3,6-DI-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL (2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine 3,4-DI-O-ACETYL-6-O-(TERT-BUTYLDIMETHYLSILYL)-D-GLUCAL 6,6'-DI-O-(TERT-BUTYLDIMETHYLSILYL)-D-LACTAL 6-O-(TERT-BUTYLDIPHENYLSILYL)-D-GLUCAL

(TERT.-BUTYLDIMETHYLSILYLOXY)ETHANOL

2-(tert-Butyl-dimethylsilanyloxy)-ethanol

2-(t-butyldimethylsiloxy)ethanol

2-(tert-ButyldiMethylsiloxy)ethyl alcohol

2-[(tert-ButyldiMethylsilyl)oxy]-1-ethanol

2-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]ethanol

Ethanol, 2-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-

2-tert-Butyldimethylsilyloxyethanol

2-((tert-ButyldiMethylsilyl)oxy)etanol-

2-(tert-Butyldimethylsiloxy)ethanol

2-[[tert-Butyl(dimethyl)silyl]oxy]ethan-1-ol

DK025

DK448

DKFELEX0097

DKSI011

CB9511523

102229-10-7

Aliphatics