Taurohyodeoxycholic acid sodium salt hydrate
- Product Name
- Taurohyodeoxycholic acid sodium salt hydrate
- CAS No.
- 38411-85-7
- Chemical Name
- Taurohyodeoxycholic acid sodium salt hydrate
- Synonyms
- Taurine pig deoxycholate sodium;Sodium taurocholic acid deoxycholate;Taurohyodeoxycholic acid sodium salt hydrate;Taurohyodeoxycholic acid hydrate sodium salt;Taurohyodeoxycholic acid sodium salt, 10 mM in DMSO;5β-CHOLANIC ACID-3α, 6α-DIOL N-(2-SULPHOETHYL)-AMIDE;Sodium taurohyodeoxycholate hydrate,Taurohyodeoxycholic acid sodium salt hydrate
- CBNumber
- CB9547458
- Molecular Formula
- C26H46NNaO6S
- Formula Weight
- 523.7
- MOL File
- 38411-85-7.mol
Taurohyodeoxycholic acid sodium salt hydrate Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
- form
- A crystalline solid
- color
- White to off-white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- T0682
- Product name
- Sodium taurohyodeoxycholate hydrate
- Purity
- anionic
- Packaging
- 250mg
- Price
- $163.1
- Updated
- 2025/07/31
- Product number
- T0682
- Product name
- Sodium taurohyodeoxycholate hydrate
- Purity
- anionic
- Packaging
- 1g
- Price
- $678
- Updated
- 2025/07/31
- Product number
- 21956
- Product name
- Taurohyodeoxycholic Acid (sodium salt)
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 21956
- Product name
- Taurohyodeoxycholic Acid (sodium salt)
- Packaging
- 25mg
- Price
- $533
- Updated
- 2024/03/01
- Product number
- 21956
- Product name
- Taurohyodeoxycholic Acid (sodium salt)
- Packaging
- 5mg
- Price
- $139
- Updated
- 2024/03/01
Taurohyodeoxycholic acid sodium salt hydrate Chemical Properties,Usage,Production
Description
Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid (TCDCA; ) prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.
Uses
Sodium taurohyodeoxycholate hydrate has been used in a study to assess dose-response data for cytotoxicity, regenerative cell proliferation and secondary oxidative DNA damage in rat livers treated with furan. It has also been used in a study to investigate the use of an immobilized artificial membrane HPLC column to predict bile salt-membrane interactions.
General Description
Sodium taurohyodeoxycholate hydrate is a taurine-amidated bile salt, which can be used as an anionic detergent.
References
[1] M ANGELICO. Dissolution of human cholesterol gallstones in bile salt/lecithin mixtures: effect of bile salt hydrophobicity and various pHs.[J]. Scandinavian Journal of Gastroenterology, 1995, 30 12: 1178-1185. DOI: 10.3109/00365529509101628
[2] M ANGELICO. Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.[J]. Digestive Diseases and Sciences, 1994, 39 11: 2389-2397. DOI: 10.1007/bf02087656
[3] ALDO RODA. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid–induced cholestasis in the rat[J]. Hepatology, 2003, 27 2: 520-525. DOI: 10.1002/hep.510270228
[4] JIAO HE . Protective effect of taurohyodeoxycholic acid from Pulvis Fellis Suis on trinitrobenzene sulfonic acid induced ulcerative colitis in mice[J]. European journal of pharmacology, 2011, 670 1: Pages 229-235. DOI: 10.1016/j.ejphar.2011.08.036
Taurohyodeoxycholic acid sodium salt hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Taurohyodeoxycholic acid sodium salt hydrate Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58
- Tel
- --
- Fax
- --
- cayman@caymanchem.com
- Country
- United States
- ProdList
- 6213
- Advantage
- 81
- Tel
- --
- Fax
- --
- Country
- United States
- ProdList
- 6773
- Advantage
- 87
View Lastest Price from Taurohyodeoxycholic acid sodium salt hydrate manufacturers
- Product
- Taurohyodeoxycholic acid sodium salt hydrate 38411-85-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 97%
- Supply Ability
- 2000
- Release date
- 2025-08-22
- Product
- Taurohyodeoxycholic acid sodium salt hydrate 38411-85-7
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99.99
- Supply Ability
- 100000
- Release date
- 2025-06-05
- Product
- Taurohyodeoxycholic acid sodium salt hydrate 38411-85-7
- Price
- US $1.00/g
- Min. Order
- 200KG
- Purity
- 99%
- Supply Ability
- 2tons
- Release date
- 2019-12-19