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1-(2-Methoxyphenyl)piperazine

Product Name
1-(2-Methoxyphenyl)piperazine
CAS No.
35386-24-4
Chemical Name
1-(2-Methoxyphenyl)piperazine
Synonyms
2-MPP;D 15157;AKOS BBS-00003584;Urapidil Impurity 6;TIMTEC-BB SBB003620;RARECHEM AH CK 0126;2-Piperazinoanisole;LABOTEST-BB LT00233095;1-(o-Anisyl)piperazine;2-(1-PIPERAZINYL)ANISOLE
CBNumber
CB9669765
Molecular Formula
C11H16N2O
Formula Weight
192.26
MOL File
35386-24-4.mol
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1-(2-Methoxyphenyl)piperazine Property

Melting point:
35-40 °C (lit.)
Boiling point:
130-133 °C/0.1 mmHg (lit.)
Density 
1.095 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.575(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Liquid After Melting
pka
8.98±0.10(Predicted)
color 
Clear colorless to yellow
Water Solubility 
Soluble in chloroform, ethyl acetate, and methanol. Insoluble in water
Sensitive 
Air Sensitive
BRN 
167888
InChI
InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3
InChIKey
VNZLQLYBRIOLFZ-UHFFFAOYSA-N
SMILES
N1(C2=CC=CC=C2OC)CCNCC1
LogP
1.67
CAS DataBase Reference
35386-24-4(CAS DataBase Reference)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
34-36/37/38
Safety Statements 
26-36/37/39-45-28A-36
RIDADR 
UN 3263 8/PG 3
WGK Germany 
3
F 
3-10
Hazard Note 
Irritant
HazardClass 
8
PackingGroup 
Ⅲ
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M22601
Product name
1-(2-Methoxyphenyl)piperazine
Purity
98%
Packaging
5g
Price
$44
Updated
2024/03/01
Sigma-Aldrich
Product number
M22601
Product name
1-(2-Methoxyphenyl)piperazine
Purity
98%
Packaging
25g
Price
$104
Updated
2024/03/01
TCI Chemical
Product number
M0883
Product name
1-(2-Methoxyphenyl)piperazine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$33
Updated
2024/03/01
TCI Chemical
Product number
M0883
Product name
1-(2-Methoxyphenyl)piperazine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$84
Updated
2024/03/01
Alfa Aesar
Product number
A15819
Product name
1-(2-Methoxyphenyl)piperazine
Purity
98%
Packaging
5g
Price
$34.4
Updated
2023/06/20
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1-(2-Methoxyphenyl)piperazine Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid after melting

Uses

A piperazine derivative and a selective antagonist at D3 receptors that influences the expression of cocaine-induced conditioned place preference (CPP).

Uses

It is used as pharmaceutical intermediate. N-alkylated 1-(2-methyoxyphenyl)piperazines markedly improved affinity and selectivity of the dopamine D3 receptor which is recognized as a potential therapeutic target for the treatment of various neurological and psychiatric disorders.

Uses

1-(2-Methoxyphenyl)piperazine can be used:

  • To functionalize pyrazolylvinyl ketones via Aza-Michael addition reaction.
  • To prepare cyclic amine substituted Tr?ger′s base derivatives.
  • To prepare functionalized bis(mercaptoimidazolyl)borates by reacting with the activated ester, [(1-methyl-2-mercaptoimidazol-5-yl)carbonyl]succinimide.

Definition

ChEBI: 1-(2-methoxyphenyl)piperazine is a member of piperazines.

1-(2-Methoxyphenyl)piperazine Preparation Products And Raw materials

Raw materials

Silica gel o-Anisidine Hexane Benzyltriethylammonium chloride 2-Diethylaminoethylchloride hydrochloride Ethyl acetate Sodium carbonate

Preparation Products

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1-(2-Methoxyphenyl)piperazine Suppliers

Americas 1 Belgium 4 Canada 1 China 194 Europe 3 France 2 Germany 13 India 24 Italy 2 Japan 4 Slovakia 1 South Korea 2 Switzerland 5 Ukraine 2 United Kingdom 19 United States 51 Global 328
MDP ChemControl Ltd.
Tel
--
Fax
--
Email
chemcontrol@nextra.sk
Country
Slovakia
ProdList
6700
Advantage
60
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View Lastest Price from 1-(2-Methoxyphenyl)piperazine manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
AochuangChem-1-(2-Methoxyphenyl)piperazine 35386-24-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-10
Henan Aochuang Chemical Co.,Ltd.
Product
1-(2-Methoxyphenyl)piperazine 35386-24-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-09
Career Henan Chemical Co
Product
1-(2-Methoxyphenyl)piperazine 35386-24-4
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-15

35386-24-4, 1-(2-Methoxyphenyl)piperazineRelated Search:

6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil 2-Methylpiperazine Piperazine N-Aminoethylpiperazine Piperacillin 2-Ethylhexyl ferulate 1-(3-AMinopropyl)-4-(2-Methoxyphenyl)piperazine 97% 4-(3-Hydroxypropylamino)-1,3-dimethyluracil O-DesMethyl Urapidil 6-[(3-chloropropyl)amino]-1,3-dimethyluracil 2-Demethoxy-2-chloro urapidil Urapidil impurity 7 1,3-Dimethylbarbituric acid 2-Demethoxy-4-methoxy urapidil 3-[4-(2-methoxyphenyl)-1-piperazinyl]propanenitrile 6-Chloro-1,3-dimethyl-2,4-(1H,3H)-pyrimidinedione 1-(4-Methoxyphenyl)piperazine Propiophenone

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