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6-Azaindole

Product Name
6-Azaindole
CAS No.
271-29-4
Chemical Name
6-Azaindole
Synonyms
1H-Pyrrolo[2,3-c]pyridine;6-Azaindol;6-Azaindole;6-Aza-1H-indole;6-Azaindole, 98+%;Harmyrine 1,6-Diazaindene;1H-PYRROLO[2,3-C]PYRIDINE 6-AZAINDOLE;6-Azaindole,1H-pyrrolo[2,3-c]pyridine;1H-Pyrrolo[2,3-c]pyridine;1H-Pyrrolo[2,3-c]pyridine (6CI, 7CI, 8CI, 9CI, ACI)
CBNumber
CB9677678
Molecular Formula
C7H6N2
Formula Weight
118.14
MOL File
271-29-4.mol
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6-Azaindole Property

Melting point:
136-137°C
Boiling point:
295.8±13.0 °C(Predicted)
Density 
1.242±0.06 g/cm3(Predicted)
RTECS 
UY8720000
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
Solid
pka
14.66±0.30(Predicted)
Appearance
Off-white to light brown Solid
Water Solubility 
Soluble in water (hardly), methanol and chloroform.
Sensitive 
Air & Light Sensitive
InChI
InChI=1S/C7H6N2/c1-3-8-5-7-6(1)2-4-9-7/h1-5,9H
InChIKey
XLKDJOPOOHHZAN-UHFFFAOYSA-N
SMILES
C1=NC=CC2C=CNC1=2
CAS DataBase Reference
271-29-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
29339980
Toxicity
mouse,LD50,intraperitoneal,12mg/kg (12mg/kg),Journal of Medicinal Chemistry. Vol. 6, Pg. 480, 1963.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS007514
Product name
1<I>H</I>-Pyrrolo[2,3-<I>c</I>]pyridine
Purity
Aldrich<SUP>CPR</SUP>
Packaging
1 g
Price
$286
Updated
2025/07/31
TCI Chemical
Product number
P2530
Product name
1H-Pyrrolo[2,3-c]pyridine
Purity
min. 98.0 %
Packaging
1G
Price
$43
Updated
2025/07/31
TCI Chemical
Product number
P2530
Product name
1H-Pyrrolo[2,3-c]pyridine
Purity
min. 98.0 %
Packaging
5G
Price
$130
Updated
2025/07/31
TRC
Product number
A965395
Product name
6-Azaindole
Packaging
2.5g
Price
$50
Updated
2021/12/16
TRC
Product number
A965395
Product name
6-Azaindole
Packaging
25g
Price
$335
Updated
2021/12/16
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6-Azaindole Chemical Properties,Usage,Production

Chemical Properties

crystals

Uses

6-Azaindole is an indole derivative and useful synthetic intermediate.

Synthesis

357263-41-3

271-29-4

General procedure for the synthesis of 6-azaindole using 7-chloro-1H-pyrrolo[2,3-c]pyridine as starting material: a suspension of 7-chloro-1H-pyrrolo[2,3-c]pyridine (650 mg, 4.2 mmol) with 10% Pd/C (50 mg) in ethanol (25 mL) was subjected to a hydrogen atmosphere (balloon pressure) and the reaction was stirred at room temperature. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filter cake was washed with ethyl acetate (10 mL). The filtrates were combined, concentrated under reduced pressure and subsequently purified by fast column chromatography (eluent: dichloromethane/methanol/ammonia, 9:1:0.1, v/v) to afford 1H-pyrrolo[2,3-c]pyridine as a white solid (380 mg, 75% yield).

References

[1] Journal of Organic Chemistry, 2002, vol. 67, # 7, p. 2345 - 2347
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 22, p. 9531 - 9540
[3] Patent: US2007/123535, 2007, A1. Location in patent: Page/Page column 43
[4] European Journal of Medicinal Chemistry, 2011, vol. 46, # 10, p. 5086 - 5098
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 10, p. 4009 - 4022

6-Azaindole Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Azaindole Suppliers

Abintio Biosciences
Tel
--
Fax
--
Country
India
ProdList
52
Advantage
58
A.J Chemicals
Tel
--
Fax
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Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 6-Azaindole manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
6-Azaindole 271-29-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-04-12
Henan Aochuang Chemical Co.,Ltd.
Product
6-Azaindole 271-29-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-29
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
6-Azaindole 271-29-4
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2021-09-14

271-29-4, 6-AzaindoleRelated Search:


  • Harmyrine 1,6-Diazaindene
  • 1H-PYRROLO[2,3-C]PYRIDINE 6-AZAINDOLE
  • 1H-Pyrrolo[2,3-c]pyridine
  • 6-Azaindole
  • 6-Azaindol
  • 6-Azaindole,1H-pyrrolo[2,3-c]pyridine
  • 6-Azaindole, 98+%
  • 6-Aza-1H-indole
  • 1H-Pyrrolo[2,3-c]pyridine (6CI, 7CI, 8CI, 9CI, ACI)
  • 1<i>H</i>-Pyrrolo[2,3-<i>c</i>]pyridine
  • 271-29-4
  • Azaindoles
  • Heterocycle-Indole series
  • Azaindole
  • Building Blocks
  • Indoles and derivatives
  • Indole
  • Heterocyclic Compounds
  • Indole Series