ChemicalBook > CAS DataBase List > Fmoc-Asp-OAll

Fmoc-Asp-OAll

Product Name
Fmoc-Asp-OAll
CAS No.
144120-53-6
Chemical Name
Fmoc-Asp-OAll
Synonyms
FMOC-L-ASP-OALL;FMOC-ASP-OAL;FMOC-ASP-OAI;FMOC-ASP-OALL;H-Fmoc-AspOAll;Fmoc-L-Asp(OAll)-OH;Fmoc-L-ASp(OAIl)-0H;FMOC-ASP-ALLYL ESTER;Icatibant Impurity 21;Fmoc-Asp-OAll USP/EP/BP
CBNumber
CB9686568
Molecular Formula
C22H21NO6
Formula Weight
395.41
MOL File
144120-53-6.mol
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Fmoc-Asp-OAll Property

Melting point:
131.0 to 135.0 °C
Boiling point:
634.8±55.0 °C(Predicted)
Density 
1.286±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in water or 1% acetic acid
form 
Powder
pka
4.09±0.19(Predicted)
color 
White
optical activity
[α]20/D 24.5±2°, c = 1% in DMF
BRN 
5460108
CAS DataBase Reference
144120-53-6(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2924 29 70
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52072
Product name
Fmoc-Asp-OAll
Purity
Novabiochem?
Packaging
1g
Price
$86.3
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52072
Product name
Fmoc-Asp-OAll
Purity
Novabiochem?
Packaging
5G
Price
$173.5
Updated
2025/07/31
Sigma-Aldrich
Product number
47578
Product name
Fmoc-Asp-OAll
Purity
≥97.0% (HPLC)
Packaging
5G
Price
$579
Updated
2025/07/31
TCI Chemical
Product number
A2894
Product name
1-Allyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartate
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$84
Updated
2025/07/31
TCI Chemical
Product number
A2894
Product name
1-Allyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$335
Updated
2025/07/31
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Fmoc-Asp-OAll Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

Fmoc-asp-oall is an intermediate used in the synthesis of some biologically active molecules.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Synthesis

144120-52-5

144120-53-6

Procedure for the synthesis of Nα-Fmoc-L-aspartic acid α-allyl ester: Nα-Fmoc-L-aspartic acid (OH) allyl ester (0.77 g; 1.94 mmol) was dissolved in a mixture of dichloromethane (DCM, 4 ml) and trifluoroacetic acid (TFA, 2 ml), and the reaction was stirred for 1 h at room temperature. After completion of the reaction, the mixture was concentrated to dryness under reduced pressure. The resulting solid was dissolved in saturated aqueous sodium bicarbonate (NaHCO3) solution and washed with ether. Subsequently, it was acidified to pH 2 with 5% hydrochloric acid (HCl) to produce a white precipitate. It was extracted twice with ethyl acetate (EE) and the organic phases were combined. The organic phase was washed with acidified water (HCl, pH 1), dried over anhydrous sodium sulfate (Na2SO4), and evaporated under reduced pressure to afford the target product Nα-Fmoc-L-aspartic acid α-allyl ester (87% yield). The product was structurally confirmed by 1H NMR (250 MHz, DMSO-d6) and 13C NMR (75 MHz, CDCl3), and the purity was verified by ESI-MS (m + Na: 418.1) and HPLC (Rt: 22.0 min, gradient 10-100%).

References

[1] Tetrahedron Letters, 1992, vol. 33, # 32, p. 4557 - 4560
[2] Chemical Communications, 2011, vol. 47, # 39, p. 10939 - 10941
[3] Carbohydrate Research, 2007, vol. 342, # 3-4, p. 541 - 557
[4] Journal of Medicinal Chemistry, 2011, vol. 54, # 21, p. 7648 - 7662
[5] Patent: US2014/39153, 2014, A1. Location in patent: Paragraph 0150; 0151; 0152

Fmoc-Asp-OAll Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-Asp-OAll Suppliers

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View Lastest Price from Fmoc-Asp-OAll manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-Asp-OAll 144120-53-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-11-16
Shaanxi Dideu Medichem Co. Ltd
Product
Fmoc-Asp-OAll 144120-53-6
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-25
Sichuan Jiaying Lai Technology Co.,LTD
Product
Fmoc-Asp-OAll 144120-53-6
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2019-07-23

144120-53-6, Fmoc-Asp-OAllRelated Search:

Fmoc-L-aspartic acid 4-benzyl ester Fmoc-L-Glutamic acid 1-tert-butyl ester Fmoc-Asp-OFm FMOC-ASN(TRT)-OPFP Nalpha-FMOC-L-Asparagine Fmoc-L-Aspartic acid-1-benzyl ester L-Fmoc-Aspartic acid alpha-tert-butyl ester Fmoc-Asn(Trt)-OH Fmoc-D-Asn(Trt)-OH Fmoc-D-Asparagine FMOC-ASN-OPFP Cbz-D-Valine Fmoc-L-aspartic acid Fmoc-Asp-OAll L-ASPARTIC ACID FMOC-ASP(OALL)-OH FMOC-ASP-OME

  • Fmoc-L-aspartic acid a-allyl ester≥ 98% (HPLC)
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Asp-OAll
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-ASPARTIC
  • (3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-oxo-4-(prop-2-en-1-yloxy)butanoic acid
  • Fmoc-L-aspartic acid α-allyl ester
  • FMOC-ASP-OAI
  • FMOC-ASP-OAL
  • FMOC-ASP-OALL
  • FMOC-ASPARTIC ACID-ALLYL ESTER
  • FMOC-ASP-ALLYL ESTER
  • FMOC-L-ASP-OALL
  • FMOC-L-ASPARTIC ACID 1-ALLYL ESTER
  • FMOC-L-ASPARTIC ACID ALPHA-ALLYL ESTER
  • N-(9-Fluorenylmethyloxycarbonyl)-L-aspartic acid alpha-allyl ester
  • Fmoc-L-Asp(OAll)-OH
  • (3S)-4-(allyloxy)-3-{[(9H-fluoren-9-ylMethoxy)carbonyl]aMino}-4-oxobutanoic acid
  • (S)-3-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-4-(allyloxy)-4-oxobutanoic acid
  • H-Fmoc-AspOAll
  • 1-Allyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartate
  • N-Fmoc-L-aspartic acid 1-allyl ester
  • N-ALPHA-FMOC-L-ASPARTIC ACID ALPHA-ALLYL ESTER
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-ASPARTIC ACID ALPHA-ALLYL ESTER
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-ASPARTIC ACID ALPHA-ALLYL ESTER
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-ASPARTIC ACID ALPHA ALLYLOXICARBONYL ESTER
  • 1-Allyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartate &gt
  • L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 1-(2-propen-1-yl) ester
  • N-α-Fmoc-L-aspartic acid α-allyl ester
  • 1-Allyl N-Fmoc-L-aspartate
  • N-[(9H-Fluoren-9-ylmethyloxycarbonyl)]-L-aspartic Acid 1-Allyl Ester
  • Fmoc-Asp-OAll USP/EP/BP
  • Fmoc-L-aspartic acid a-allyl ester
  • Fmoc-L-Asparticacidα-allylester
  • Fmoc-L-Aspartate-1-Allyl ester
  • Fmoc-L-ASp(OAIl)-0H
  • Icatibant Impurity 21
  • 144120-53-6
  • C22H21NO6
  • Analytical Chromatography Product Catalog
  • Analytical Standards
  • Alphabetic
  • FM - FZ
  • Aspartic acid [Asp, D]
  • Fmoc-Amino Acids and Derivatives
  • Fmoc-Amino acid series
  • amino acids