Mesterolone

Product Name: Mesterolone
CAS No.: 1424-00-6
Chemical Name: Mesterolone
Synonyms: proviron;mesterolon;MESTERELONE;testiwop;sh723;NSC-7504;NSC 75054;mesteranum;androviron;mestoranum
CBNumber: CB9691874
Molecular Formula: C20H32O2
Formula Weight: 304.47
MOL File: 1424-00-6.mol

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Mesterolone Property

Melting point:: 208 °C
alpha: D20 +17.6° (c = 0.875 in CHCl3)
Boiling point:: 420.3±45.0 °C(Predicted)
Density: 1.156 g/cm3
refractive index: 17.6 ° (C=0.9, CHCl3)
storage temp.: 2-8°C
solubility: Practically insoluble in water, sparingly soluble in acetone, in ethyl acetate and in methanol
pka: 15.09±0.70(Predicted)
Water Solubility: 3mg/L at 20℃
Merck: 5916
InChI: InChI=1/C20H32O2/c1-12-10-14(21)11-13-4-5-15-16-6-7-18(22)19(16,2)9-8-17(15)20(12,13)3/h12-13,15-18,22H,4-11H2,1-3H3/t12-,13-,15-,16-,17-,18-,19-,20-/s3
InChIKey: UXYRZJKIQKRJCF-TZPFWLJSSA-N
SMILES: [C@@]12([H])CC[C@@]3([H])CC(=O)C[C@H](C)[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])O |&1:0,4,10,12,14,18,20,23,r|
CAS DataBase Reference: 1424-00-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,T,F
Risk Statements: 20/21/22-38-19-11-61-60
Safety Statements: 22-24/25-36/37/39-45-53
WGK Germany: 3
RTECS: BV8063400
HS Code: 29372900
DEA Controlled Substances: CSCN: 4000
CSA SCH: Schedule III
NARC: No

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H351Suspected of causing cancer

H362May cause harm to breast-fed children

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M7655
Product name: Mesterolone
Purity: analytical standard
Packaging: 100mg
Price: $95.1
Updated: 2024/03/01

Cayman Chemical

Product number: 21171
Product name: Mesterolone
Purity: ≥95%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 21171
Product name: Mesterolone
Purity: ≥95%
Packaging: 5mg
Price: $109
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: SHG0006368
Product name: MESTEROLONE
Purity: 95.00%
Packaging: 250MG
Price: $721.88
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0006368
Product name: MESTEROLONE
Purity: 95.00%
Packaging: 2.5G
Price: $1815
Updated: 2021/12/16

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Mesterolone Chemical Properties,Usage,Production

Description

Mesterolone (Item No. 21171) is an analytical reference standard categorized as an anabolic androgenic steroid. Formulations containing mesterolone have been used in patients with low testosterone or symptoms of aging male syndrome. Mesterolone cannot be aromatized to estrogens, unlike other androgens. This compound is the active ingredient in different pharmaceutical preparations that have been used medically but have also been widely applied in sports in order to improve athlete performance. Mesterolone is regulated as a Schedule III drug in the United States. This product is intended for research and forensic applications.

Chemical Properties

White or yellowish crystalline powder.

Originator

Proviron,Schering,W. Germany,1967

Uses

Mesterolone is a synthetic androgen and a dihydrotestosterone derivative. Mesterolone is rarely used for replacement therapies due to its weak androgenic activity.

Definition

ChEBI: Mesterolone is a 3-oxo-5alpha-steroid. It is a structurally altered DHT hormone possessing the addition of a methyl group at the carbon one position. This allows the hormone to survive oral ingestion by protecting it from hepatic breakdown. This is one of the only oral anabolic steroids that is not C17-alpha alkylated (C17-aa) but instead carries the added methyl group.

Application

Mesterolone is a pharmacological agent that belongs to the group of androgens. It is an oral preparation and has been used in the treatment of infectious diseases, autoimmune diseases, and metabolic disorders. It has also been used as a matrix effect control in biological samples. The biological effects of it are mediated by its direct action on cells or through conversion to testosterone or dihydrotestosterone (DHT). These effects include increasing protein synthesis, promoting bone formation, lowering cholesterol levels, stimulating the production of red blood cells, and decreasing fat deposition.

Manufacturing Process

500 mg of 1α-methyl-androstan-17β-ol-3-one-17-acetate are heated under reflux for 90 minutes in a nitrogen atmosphere in 5 ml of 4% methanolic sodium hydroxide solution. The reaction mixture is then stirred into ice water,the precipitated product filtered with suction and recrystallized from isopropyl ether. 1α-Methyl-androstan-17β-ol-3-one melts at 203.5° to 205°C.

Therapeutic Function

Androgen

General Description

Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT). It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. Mesterolone demonstrated to have minimal effect on sperm counts and levels of FSH or LH. Experiments of mesterolone serving as a potential treatment of depression are still undergoing.

Side effects

The main side effects are acne vulgaris, male pattern baldness, prostate enlargement, increased risk for prostate cancer, and increased risk for developing breast cancer.

Mesterolone Preparation Products And Raw materials

Raw materials

Preparation Products

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Mesterolone Suppliers

Belgium 2 Brazil 1 Canada 2 China 225 Europe 3 France 1 Germany 3 India 31 Japan 1 Nigeria 1 Switzerland 1 United Kingdom 8 United States 22 Global 301

LGM Pharma

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Protheragen-ING

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Matrix Scientific

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3B Scientific Corporation

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Waterstone Technology, LLC

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Cayman Chemical Company

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Selleck Chemicals LLC

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United States Biological

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Riedel-de Haen AG

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Conscientia Industrial Co., Ltd.

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Cerilliant Corporation

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2A PharmaChem USA

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3B Scientific Corporation

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Manus Aktteva, India.

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Lab Express

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Drefspharma Ltd.

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Steraloids Inc.

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Research Plus, Inc.

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Alltech Associates, Inc.

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American Custom Chemicals Corporation

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QVENTAS INC.

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AK Scientific, Inc.

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View Lastest Price from Mesterolone manufacturers

CONTIDE BIOTECH CO.,LTD

Product: Mesterolone (Proviron) 1424-00-6
Price: US $0.00/G
Min. Order: 1G
Purity: 20
Supply Ability: 20
Release date: 2024-04-11

hebei hongtan Biotechnology Co., Ltd

Product: Mesterolone(Proviron) 1424-00-6
Price: US $12.00-8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2024-05-11

American HealthyMorph LLC

Product: Mesterolone 1424-00-6
Price: US $0.00/Box
Min. Order: 1Box
Purity: 99%
Supply Ability: 1000/week
Release date: 2024-12-12

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US Testosterone

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1α-Methyl-17β-hydroxy-5α-androstan-3-one

1α-Methyl-5α-dihydrotestosterone

NSC 75054

Mesterolone(Proviron)

sh723

testiwop

1ALPHA-METHYLANDROSTAN-17BETA-OL-3-ONE

17beta-hydroxy-1alpha-methyl-5alpha-androstan-3-one

5-ALPHA-ANDROSTAN-1-ALPHA-METHYL-17-BETA-OL-3-ONE

MESTERELONE

MESTERLONE

MESTEROLONE

17β-Hydroxy-1α-methyl-5α-androstan-3-one

1α-Methyl-5α-androstan-17β-ol-3-one

1α-methylandrostan-17β-ol-3-one

(1S,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-1,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one

PROVIRONE25

mesterolone standard solution

MesteroloneAcetateBase

Mesteronlone

17b-Hydroxy-1a-methyl-5a-androstan-3-one

1a-Methylandrostan-17b-ol-3-one

NSC-7504

Mesterolon (proviron)

Mesterolone Proviron powder

Mesterolone Proviron \mesterolone

Mesterolon skype : honestcooperation

Mesterolone CRS

Androstan-3-one, 17-hydroxy-1-methyl-, (1α,5α,17β)-

mesterolone standard solution, 100ppm

The testosterone

Mesterolone(Proviron, PRO)-1 gram(13)

Mesterolone powder

MesteroloneQ: What is Mesterolone Q: What is the CAS Number of Mesterolone Q: What is the storage condition of Mesterolone

Mesterolone RAW

masterolone

Androstan-3-one, 17-hydroxy-1-methyl-, (1α,5α,17β)-